Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jineng Lv"'
Autor:
Junhao Fu, Qing Li, Xiaoyu Liu, Tianxiang Tu, Xiujuan Lv, Xidi Yin, Jineng Lv, Zongming Song, Jia Qu, Jinwei Zhang, Jinsong Li, Feng Gu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Application of adenine base editors (ABE) has been precluded by low activity. Here the authors show the generation of a human cell based ABE directional screening system and identification of ABE variant (NG-ABEmax-KR) exhibiting a significant increa
Externí odkaz:
https://doaj.org/article/d0f00b9c200741e59b1418eaed8eed7c
Autor:
Tianxiang Tu, Zongming Song, Xiaoyu Liu, Shengxing Wang, Xiaoxue He, Haitao Xi, Jiahua Wang, Tong Yan, Haoran Chen, Zhenwu Zhang, Xiujuan Lv, Jineng Lv, Xiu-Feng Huang, Junzhao Zhao, Chao-Po Lin, Caixia Gao, Jinwei Zhang, Feng Gu
Publikováno v:
Molecular Therapy. 30:2933-2941
Adenine base editors (ABEs) are novel genome-editing tools, and their activity has been greatly enhanced by eight additional mutations, thus named ABE8e. However, elevated catalytic activity was concomitant with frequent generation of bystander mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a4c72473e1f3f7065c85c08e5adc265
https://doi.org/10.1016/j.ymthe.2022.07.010
https://doi.org/10.1016/j.ymthe.2022.07.010
Autor:
Xiujuan Lv, Zheng Zheng, Xiao Zhi, Yilin Zhou, Jineng Lv, Yue Zhou, Binrong Wu, Sixiu Liu, Wei Shi, Zongming Song, Jinling Xu, Jia Qu, Dan Xu, Feng Gu
Publikováno v:
Gene Therapy. 30:160-166
X-linked retinitis pigmentosa (XLRP) is the most severe form of Retinitis Pigmentosa (RP) and one of the leading causes of blindness in the world. Currently, there is no effective treatment for RP. In the present study, we recruited a XLRP family and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c26cd89b451b75b7fdcf6976a65c1c
https://doi.org/10.1038/s41434-022-00352-3
https://doi.org/10.1038/s41434-022-00352-3
Autor:
Jineng Lv, Haitao Xi, Xiujuan Lv, Yue Zhou, Jiahua Wang, Haoran Chen, Tong Yan, Jiang Jin, Junzhao Zhao, Feng Gu, Zongming Song
Publikováno v:
Gene Therapy. 29:458-463
CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated endonuclease Cas9) nucleases have been widely applied for genome engineering. Staphylococcus aureus Cas9 (SaCas9) is compact, which can be packaged in AAV (adeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fe370dafec7aaec11639e2c7e5e0ddc
https://doi.org/10.1038/s41434-022-00319-4
https://doi.org/10.1038/s41434-022-00319-4
Autor:
Lue Xiang, Qi Chen, Kunchao Wu, Xuejiao Chen, Huanyun Yu, Shengjin Xiang, Bintao Xie, Jineng Lv, Fengqin Rao, Liujun Ding, Jingrun Chen, Qiaoli Yang, Huiyi Zeng
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a406a115f9d2dc6c7f75fb386663089b
https://doi.org/10.3791/64783
https://doi.org/10.3791/64783
Publikováno v:
Scientific Reports; 2/21/2014, p1-6, 6p
Autor:
Xiexie Liu1, Xiaoyu Liu1, Chenchen Zhou1, Jineng Lv1, Xiubin He1, Yuanyuan Liu1, Haihua Xie1, Bang Wang1, Xiujuan Lv1, Lianchao Tang1, Mingchun Li1, Changbao Liu2, Junzhao Zhao2, Yong Liu1, Zongming Song1,3, Feng Gu1 gufenguw@gmail.com
Publikováno v:
Journal of Biological Chemistry. Jan-Jun2021, Vol. 296, p1-10. 10p.