Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jinendiran Sekar"'
Autor:
Amy H. Attaway, Annette Bellar, Nicole Welch, Jinendiran Sekar, Avinash Kumar, Saurabh Mishra, Umur Hatipoğlu, Merry‐Lynn McDonald, Elizabeth A. Regan, Jonathan D. Smith, George Washko, Raúl San José Estépar, Peter Bazeley, Joe Zein, Srinivasan Dasarathy
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 1083-1095 (2023)
Abstract Background Sarcopenia, or loss of skeletal muscle mass and decreased contractile strength, contributes to morbidity and mortality in patients with chronic obstructive pulmonary disease (COPD). The severity of sarcopenia in COPD is variable,
Externí odkaz:
https://doaj.org/article/62aaf16a8ff94490b943c20b2a887b98
Autor:
Annette Bellar, Nicole Welch, Jaividhya Dasarathy, Amy Attaway, Ryan Musich, Avinash Kumar, Jinendiran Sekar, Saurabh Mishra, Yana Sandlers, David Streem, Laura E Nagy, Srinivasan Dasarathy
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background Patients with acute alcohol‐associated hepatitis (AH) have immune dysfunction. Mitochondrial function is critical for immune cell responses and regulates senescence. Clinical translational studies using complementary bioinformat
Externí odkaz:
https://doaj.org/article/881a67875696428382c69cb550c103a6
Autor:
Nicole Welch, Shashi Shekhar Singh, Ryan Musich, M. Shahid Mansuri, Annette Bellar, Saurabh Mishra, Aruna K. Chelluboyina, Jinendiran Sekar, Amy H. Attaway, Ling Li, Belinda Willard, Troy A. Hornberger, Srinivasan Dasarathy
Publikováno v:
iScience, Vol 25, Iss 11, Pp 105325- (2022)
Summary: Skeletal muscle generation of ammonia, an endogenous cytotoxin, is increased during exercise. Perturbations in ammonia metabolism consistently occur in chronic diseases, and may blunt beneficial skeletal muscle molecular responses and protei
Externí odkaz:
https://doaj.org/article/58ed0697bcec441494f70e8cf21d93b0
Autor:
Shashi Shekhar Singh, Avinash Kumar, Nicole Welch, Jinendiran Sekar, Saurabh Mishra, Annette Bellar, Mahesha Gangadhariah, Amy Attaway, Hayder Al Khafaji, Xiaoqin Wu, Vai Pathak, Vandana Agrawal, Megan R. McMullen, Troy A. Hornberger, Laura E. Nagy, Gangarao Davuluri, Srinivasan Dasarathy
Publikováno v:
Cellular Physiology and Biochemistry, Vol 55, Iss 1, Pp 91-116 (2021)
Externí odkaz:
https://doaj.org/article/149adb9bba314f0284ac3b35b53225aa
Autor:
Avinash Kumar, Nicole Welch, Saurabh Mishra, Annette Bellar, Rafaella Nasciemento Silva, Ling Li, Shashi Shekhar Singh, Mary Sharkoff, Alexis Kerr, Aruna Kumar Chelluboyina, Jinendiran Sekar, Amy H. Attaway, Charles Hoppel, Belinda Willard, Gangarao Davuluri, Srinivasan Dasarathy
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
Ammonia is a cytotoxic metabolite with pleiotropic molecular and metabolic effects, including senescence induction. During dysregulated ammonia metabolism, which occurs in chronic diseases, skeletal muscle becomes a major organ for nonhepatocyte ammo
Externí odkaz:
https://doaj.org/article/0ebae34ec55e4a5d9fee0cbae28c8a7f
Autor:
Sathishkumar, Ramamoorthy, Kannan, Ramachandran, Jinendiran, Sekar, Sivakumar, Natesan, Selvakumar, Gopal, Shyamkumar, Rajaram
Publikováno v:
In International Journal of Biological Macromolecules 1 January 2021 166:1471-1479
Autor:
Amy H. Attaway, Annette Bellar, Saurabh Mishra, Manikandan Karthikeyan, Jinendiran Sekar, Nicole Welch, Ryan Musich, Shashi Shekhar Singh, Avinash Kumar, Aishwarya Menon, Jasmine King, Ramon Langen, Justine Webster, Rachel G. Scheraga, Kristy Rochon, Jason Mears, Sathyamangla V. Naga Prasad, Maria Hatzoglou, Abhishek A. Chakraborty, Srinivasan Dasarathy
Publikováno v:
The Journal of Physiology, 601(3), 567-606. Wiley-Blackwell
KEY POINTS: Sarcopenia or skeletal muscle loss is one of the most frequent complications that contributes to mortality and morbidity in patients with chronic obstructive pulmonary disease (COPD). Unlike chronic hypoxia, prolonged intermittent hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed0bb6a32c36206eeedb85ac4dfdd00
https://doi.org/10.1113/JP283700
https://doi.org/10.1113/JP283700
Autor:
Amy Attaway, Jinendiran Sekar, Saurabh Mishra, Annette Bellar, Jason Mears, Nicolaas Deutz, Marielle Engelen, Srinivasan Dasarathy
Publikováno v:
Physiology. 38
Background: Sarcopenia, or skeletal muscle loss, is common complication in COPD and contributes to adverse clinical outcomes including mortality. As the disease progresses, a significant proportion of COPD patients develop nocturnal hypoxemia which c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e76e8764e2b25a28e0f1c2560595bd4
https://doi.org/10.1152/physiol.2023.38.s1.5733211
https://doi.org/10.1152/physiol.2023.38.s1.5733211
Autor:
Saurabh Mishra, Nicole Welch, Manikandan Karthikeyan, Annette Bellar, Ryan Musich, Shashi Shekhar Singh, Dongmei Zhang, Jinendiran Sekar, Amy H. Attaway, Aruna Kumar Chelluboyina, Shuhui Wang Lorkowski, Sanjoy Roychowdhury, Ling Li, Belinda Willard, Jonathan D. Smith, Charles L. Hoppel, Vidula Vachharajani, Avinash Kumar, Srinivasan Dasarathy
Publikováno v:
Aging Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::facd9d55f010b78d202ae2d7d15b87cf
https://doi.org/10.1111/acel.13852
https://doi.org/10.1111/acel.13852