Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Jindřich Hašek"'
Autor:
Jan Bláha, Tereza Skálová, Barbora Kalousková, Ondřej Skořepa, Denis Cmunt, Valéria Grobárová, Samuel Pazicky, Edita Poláchová, Celeste Abreu, Jan Stránský, Tomáš Kovaľ, Jarmila Dušková, Yuguang Zhao, Karl Harlos, Jindřich Hašek, Jan Dohnálek, Ondřej Vaněk
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
NKR-P1 is an inhibitory receptor on the surface of natural killer cells, and its engagement with the ligand LLT1 on activated monocytes and B cells triggers NK cell self-tolerance and other immunological processes. Here authors set up a comprehensive
Externí odkaz:
https://doaj.org/article/2886da344a5c4fb5b7cd879fe5b82c44
Autor:
Tomáš Kovaľ, Lars H Østergaard, Jan Lehmbeck, Allan Nørgaard, Petra Lipovová, Jarmila Dušková, Tereza Skálová, Mária Trundová, Petr Kolenko, Karla Fejfarová, Jan Stránský, Leona Švecová, Jindřich Hašek, Jan Dohnálek
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168832 (2016)
The single-strand-specific S1 nuclease from Aspergillus oryzae is an archetypal enzyme of the S1-P1 family of nucleases with a widespread use for biochemical analyses of nucleic acids. We present the first X-ray structure of this nuclease along with
Externí odkaz:
https://doaj.org/article/5e39077b1a484a4ebb64b13431b459bd
Autor:
Jindřich Hašek
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 77:C931-C931
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5d55f641a7be43dbaf3330d9b6483b
https://doi.org/10.1107/s0108767321087687
https://doi.org/10.1107/s0108767321087687
Autor:
Jan Stránský, Petr Kolenko, Mária Trundová, Tomáš Kovaľ, Lars Henrik Østergaard, Jan Dohnálek, Tereza Skálová, Karla Fejfarová, Jindřich Hašek, Leona Svecova, Jarmila Dušková
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Unlike any protein studied so far, the active site of bilirubin oxidase from Myrothecium verrucaria contains a unique type of covalent link between tryptophan and histidine side chains. The role of this post-translational modification in substrate bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ec1b4a6d18f5fddd614ca5d6e6a161
https://doi.org/10.1038/s41598-019-50105-3
https://doi.org/10.1038/s41598-019-50105-3
Autor:
Anna Týcová, Jan Stránský, Tomáš Koval, Jarmila Dušková, Jaroslav Matoušek, Jan Dohnálek, Petr Kolenko, Tereza Skálová, Karla Fejfarová, Jindřich Hašek, Tomáš Podzimek, Petra Lipovová
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 71:1408-1415
Tomato multifunctional nuclease TBN1 belongs to the type I nuclease family, which plays an important role in apoptotic processes and cell senescence in plants. The newly solved structure of the N211D mutant is reported. Although the main crystal-pack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::849e44c66a1a5c9cfedb5689ff35bd1e
https://doi.org/10.1107/s2053230x15018324
https://doi.org/10.1107/s2053230x15018324
Autor:
T. Kovaĺová, T. Kovaĺ, Leona Svecova, Tereza Skálová, Jan Dohnálek, Jarmila Dušková, Jindřich Hašek, Petr Kolenko
Publikováno v:
Acta Crystallographica Section A Foundations and Advances. 74:e407-e408
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::844c962e21fe91a23911e0a7a6ccfe04
https://doi.org/10.1107/s2053273318089076
https://doi.org/10.1107/s2053273318089076
Autor:
Jindřich Hašek, Lars Henrik Østergaard, Jarmila Dušková, Tomáš Kovaľ, Jan Dohnálek, Karla Fejfarová, Petra Lipovová, Petr Kolenko, Tereza Skálová, Leona Svecova, Jan Stránský, Mária Trundová, Allan Nørgaard, Jan Lehmbeck
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168832 (2016)
PLoS ONE
PLoS one 11(12), e0168832-(2016). doi:10.1371/journal.pone.0168832
PLoS ONE
PLoS one 11(12), e0168832-(2016). doi:10.1371/journal.pone.0168832
PLoS one 11(12), e0168832 -(2016). doi:10.1371/journal.pone.0168832
The single–strand–specific S1 nuclease from Aspergillus oryzae is an archetypal enzyme of the S1–P1 family of nucleases with a widespread use for biochemical analyses of n
The single–strand–specific S1 nuclease from Aspergillus oryzae is an archetypal enzyme of the S1–P1 family of nucleases with a widespread use for biochemical analyses of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f639583734959f3f2495c7643d8b28a1
Autor:
Anna Bujacz, John W. Erickson, Ramnarayan S. Randad, Tereza Skálová, Grzegorz Bujacz, Natasza E. Ziółkowska, Jindřich Hašek
Publikováno v:
Chemical Biology & Drug Design. 79:798-809
Four novel linear non-peptidic HIV-1 protease inhibitors derived from 2,5-diamino-1,6-diphenyl-3-hexanol were synthesized and characterized. All of them exhibit tight binding to HIV-1 protease, with inhibition constants Ki in the range 20 pm–5 nm.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7ebda76c9edc0907b3134dad870e69f
https://doi.org/10.1111/j.1747-0285.2012.01328.x
https://doi.org/10.1111/j.1747-0285.2012.01328.x
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 67:1519-1523
The structure of the H107R variant of the extracellular domain of the mouse natural killer cell receptor NKR-P1A has been determined by X-ray diffraction at 2.3 Å resolution from a merohedrally twinned crystal. Unlike the structure of the wild-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa02f4ba254f44a26785dd1c68757c66
https://doi.org/10.1107/s1744309111046203
https://doi.org/10.1107/s1744309111046203
Autor:
Ondřej Vaněk, Jindřich Hašek, Jan Dohnálek, Petr Pompach, Karel Bezouška, Tereza Skálová, Daniel Rozbeský, Kateřina Hofbauerová, Petr Kolenko, Petr Novák, Vladimír Kopecký
Publikováno v:
Journal of Structural Biology. 175:434-441
Receptors belonging to NKR-P1 family and their specific Clr ligands form an alternative missing self recognition system critical in immunity against tumors and viruses, elimination of tumor cells subjected to genotoxic stress, activation of T cell de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60366b9a426ca9b62bfe5ae066ab0f1
https://doi.org/10.1016/j.jsb.2011.05.001
https://doi.org/10.1016/j.jsb.2011.05.001