Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jinchao Lou"'
Autor:
Yue Zhou, Gregory A. Phelps, Mikayla M. Mangrum, Jemma McLeish, Elise K. Phillips, Jinchao Lou, Christelle F. Ancajas, Jeffrey M. Rybak, Peter M. Oelkers, Richard E. Lee, Michael D. Best, Todd B. Reynolds
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTSystemic infections by Candida spp. are associated with high mortality rates, partly due to limitations in current antifungals, highlighting the need for novel drugs and drug targets. The fungal phosphatidylserine synthase, Cho1, from Candida
Externí odkaz:
https://doaj.org/article/78c37e13beb64762ba0868b9367af010
Harnessing Clickable Acylated Glycerol Probes as Chemical Tools for Tracking Glycerolipid Metabolism
Autor:
Christelle F. Ancajas, Adam J. Carr, Jinchao Lou, Ruhani Sagar, Yue Zhou, Todd B. Reynolds, Michael D. Best
Publikováno v:
Chemistry – A European Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92fcdbc7954e604c64daf2b0870f4c0d
https://doi.org/10.1002/chem.202300417
https://doi.org/10.1002/chem.202300417
Publikováno v:
Organicbiomolecular chemistry.
In this work, we report triggered content release from liposomes brought about by copper chelation to a synthetic lipid switch containing a picolinamide headgroup. Fluorescence-based dye-leakage assays showcase release of carboxyfluorescein dye cargo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b64e24384421cce2def1ce6be3a1ff
https://pubmed.ncbi.nlm.nih.gov/36622111
https://pubmed.ncbi.nlm.nih.gov/36622111
Publikováno v:
Chembiochem : a European journal of chemical biology.
Liposomes are highly effective nanocarriers for encapsulating and delivering a wide range of therapeutic cargo. While advancements in liposome design have improved several pharmacological characteristics, an important area that would benefit from fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cfa4c25fe973c6d9d04fb363c0f7ff1
https://pubmed.ncbi.nlm.nih.gov/36164720
https://pubmed.ncbi.nlm.nih.gov/36164720
Autor:
Megan L. Qualls, Hannah Hagewood, Jinchao Lou, Samuel I. Mattern‐Schain, Xiaoyu Zhang, Deidra J. Mountain, Michael D. Best
Publikováno v:
ChemBioChem. 23
Liposomes are effective therapeutic nanocarriers due to their ability to encapsulate and enhance the pharmacokinetic properties of a wide range of drugs and diagnostic agents. A primary area in which improvement is needed for liposomal drug delivery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79271bc4b57a942a580c16fed9af3571
https://doi.org/10.1002/cbic.202200402
https://doi.org/10.1002/cbic.202200402
Publikováno v:
Chemistry – A European Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af77457c3f661d8da7b0ef36674374f4
https://doi.org/10.1002/chem.202202129
https://doi.org/10.1002/chem.202202129
Publikováno v:
Bioorganic & Medicinal Chemistry. 87:117301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::556e9232eb3d66429746a3680dadf1b5
https://doi.org/10.1016/j.bmc.2023.117301
https://doi.org/10.1016/j.bmc.2023.117301
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(45)
Liposomes are effective therapeutic delivery nanocarriers due to their ability to encapsulate and enhance the pharmacokinetic properties of a wide range of therapeutics. Two primary areas in which improvement is needed for liposomal drug delivery is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157e5363a3ae30424e8485d4aa4604ba
https://pubmed.ncbi.nlm.nih.gov/35699671
https://pubmed.ncbi.nlm.nih.gov/35699671
Autor:
Jinchao Lou, Megan L. Qualls, Macy M. Hudson, Dillon P. McBee, Joshua A. Baccile, Michael D. Best
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(46)
We report boronate-caged guanidine-lipid 1 that activates liposomes for cellular delivery only upon uncaging of this compound by reactive oxygen species (ROS) to produce cationic lipid products. These liposomes are designed to mimic the exceptional c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3310237b98b5bcc1fa35203d5330cfe5
https://pubmed.ncbi.nlm.nih.gov/35639353
https://pubmed.ncbi.nlm.nih.gov/35639353
Publikováno v:
Chemical communications (Cambridge, England). 58(28)
Liposome cargo release triggered by IP3 is achieved using a synthetic lipid switch designed to undergo conformational changes upon binding.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8716eb44ebbf1c76d29b29a63e79461c
https://pubmed.ncbi.nlm.nih.gov/35302139
https://pubmed.ncbi.nlm.nih.gov/35302139