Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jinbo Yuan"'
Publikováno v:
Meitan kexue jishu, Vol 52, Iss 3, Pp 139-147 (2024)
Aiming at the problem of high leakage rate and false alarm rate of traditional statistical methods for abnormal fluctuation in sensor monitoring data caused by dampers opening and closing, a SSA-LSTM wind speed abnormal fluctuation detection method b
Externí odkaz:
https://doaj.org/article/da7cbacfb66e452a8be5879d66928085
Publikováno v:
Journal of Orthopaedic Translation, Vol 45, Iss , Pp 178-187 (2024)
Background: Glucocorticoid-induced osteonecrosis of the femoral head (GIONFH) is a common bone and joint disease. There is currently a lack of effective treatment for GIONFH, and the disease progression may lead to total hip arthroplasty (THA). The e
Externí odkaz:
https://doaj.org/article/6159720fad654f65a47bae6c73455de8
Autor:
Jacob Kenny, Benjamin H. Mullin, William Tomlinson, Brett Robertson, Jinbo Yuan, Weiwei Chen, Jinmin Zhao, Nathan J. Pavlos, John P. Walsh, Scott G. Wilson, Jennifer Tickner, Grant Morahan, Jiake Xu
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Objectives Osteoarthritis (OA) is a joint disease with a heritable component. Genetic loci identified via genome-wide association studies (GWAS) account for an estimated 26.3% of the disease trait variance in humans. Currently, there is no m
Externí odkaz:
https://doaj.org/article/aac95cd716db4822bae59acc5d45e557
Autor:
Jianbo He, Kai Chen, Tiancheng Deng, Jiewei Xie, Kunjing Zhong, Jinbo Yuan, Ziyi Wang, Zhifeng Xiao, Ronghe Gu, Delong Chen, Xiaojuan Li, Dingkun Lin, Jiake Xu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/0d5a6e90572c4c7e96bedd8a97221540
Autor:
Pei Ying Ng, Amy B. P. Ribet, Qiang Guo, Benjamin H. Mullin, Jamie W. Y. Tan, Euphemie Landao-Bassonga, Sébastien Stephens, Kai Chen, Jinbo Yuan, Laila Abudulai, Maike Bollen, Edward T. T. T. Nguyen, Jasreen Kular, John M. Papadimitriou, Kent Søe, Rohan D. Teasdale, Jiake Xu, Robert G. Parton, Hiroshi Takayanagi, Nathan J. Pavlos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Despite the importance of osteoclast secretory lysosomes in bone digestion, the proteins that regulate them remain ill defined. Here, the authors identify Slc37a2 as a secretory lysosome sugar transporter that is required for maintenance of skeletal
Externí odkaz:
https://doaj.org/article/cfbfda3751ad47868d62c17e221301bd
Autor:
Haomeng Wang, Zhao Chen, Zhenghua Wang, Jin Li, Zhihong Yan, Jinbo Yuan, Airu Zhu, Lan Chen, Ye Liu, Chenlong Hu, Ali Zhu, Guowei Li, Yuehu Li, Jie Deng, Liqiao Ma, Xiuwen Sui, Wei Miao, Junqiang Li, Xiuyu Zheng, Jinhua Piao, Yanfeng Yao, Juhong Rao, Chao Shan, Zhiming Yuan, Jincun Zhao, Tao Zhu
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1550-1553 (2022)
In order to overcome the pandemic of COVID-19, messenger RNA (mRNA)-based vaccine has been extensively researched as a rapid and versatile strategy. Herein, we described the immunogenicity of mRNA-based vaccines for Beta and the most recent Omicron v
Externí odkaz:
https://doaj.org/article/d45010f5b7974a4ea6d38515af71876f
Autor:
Qingqing Wang, Delong Chen, Yining Wang, Chenlin Dong, Jian Liu, Kai Chen, Fangming Song, Chao Wang, Jinbo Yuan, Rohan A. Davis, Vincent Kuek, Haiming Jin, Jiake Xu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 154, Iss , Pp 113622- (2022)
Osteoclasts play an important role in maintaining the relative stability of bone mass. Abnormal number and function of osteoclasts are closely related to osteoporosis and osteolytic diseases. Thiaplakortone B (TPB), a natural compound derived from th
Externí odkaz:
https://doaj.org/article/227ad4820b88454781063235227d0673
Autor:
Gang Wang, Chao Ma, Kai Chen, Ziyi Wang, Heng Qiu, Delong Chen, Jianbo He, Cheng Zhang, Ding Guo, Boyong Lai, Shuangxiao Zhang, Linfeng Huang, Fan Yang, Jinbo Yuan, Leilei Chen, Wei He, Jiake Xu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Osteoporosis, which typically affects postmenopausal women, is an osteolytic disease due to over-activation of osteoclasts. However, current drugs targeting osteoclast inhibition face various side effects, making natural compounds with great interest
Externí odkaz:
https://doaj.org/article/e39f6d479cb74d1c93b234190edb46b3
Autor:
Jianbo He, Kai Chen, Tiancheng Deng, Jiewei Xie, Kunjing Zhong, Jinbo Yuan, Ziyi Wang, Zhifeng Xiao, Ronghe Gu, Delong Chen, Xiaojuan Li, Dingkun Lin, Jiake Xu
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The extravagant osteoclast formation and resorption is the main cause of osteoporosis. Inhibiting the hyperactive osteoclastic resorption is considered as an efficient treatment for osteoporosis. Rhaponticin (RH) is a small molecule that has been rep
Externí odkaz:
https://doaj.org/article/7fc13bf959d14396ad541d139c76e7db
Autor:
Delong Chen, Qingqing Wang, Ying Li, Ping Sun, Vincent Kuek, Jinbo Yuan, Junzheng Yang, Longfei Wen, Haibin Wang, Jiake Xu, Peng Chen
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Integrity of the skeleton is sustained through the balanced activities of osteoblasts and osteoclasts in bone remodeling unit. The balance can be disrupted by excessive osteoclasts activation commonly seen in osteoporosis. Notopterol (NOT) is a main
Externí odkaz:
https://doaj.org/article/6063d4020e3c43faa0a42367303f0bf4