Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jinbo Han"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The circadian clock regulates rhythms of physiology and metabolism in response to environmental cues such as food intake. Here, the authors show that tight junction protein 1 (TJP1) interacts with period 1 and modulates its nuclear translocation in a
Externí odkaz:
https://doaj.org/article/37f9ac0b72c64340ab9b1c2bcfe00ca2
Autor:
Zhenzhen Zhu, Weiqing Wang, Yang Zha, Xiaowei Wang, Lei Wang, Jinbo Han, Jianmin Zhang, Wei Lv
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Background: The pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNP) and mechanisms underlying different responses to systemic glucocorticoids (GC) remain unclear. The major aim of this study was to explore the transcriptomic and oxidati
Externí odkaz:
https://doaj.org/article/a84d94e3e7cf4881a0ae0c55c4fd5f50
Publikováno v:
Protein & Cell, Vol 10, Iss 8, Pp 583-594 (2019)
Abstract A change in the metabolic flux of glucose from mitochondrial oxidative phosphorylation (OXPHOS) to aerobic glycolysis is regarded as one hallmark of cancer. However, the mechanisms underlying the metabolic switch between aerobic glycolysis a
Externí odkaz:
https://doaj.org/article/07cb404e2cd34dc9a834199475378612
Publikováno v:
Protein & Cell, Vol 9, Iss 8, Pp 729-732 (2018)
Externí odkaz:
https://doaj.org/article/23ae8ac4fb0a4f4f9aac999b92a02719
Autor:
Jinbo Han, Yiguo Wang
Publikováno v:
Protein & Cell, Vol 9, Iss 2, Pp 145-151 (2017)
ABSTRACT The mechanistic target of rapamycin (mTOR) signaling pathway regulates many metabolic and physiological processes in different organs or tissues. Dysregulation of mTOR signaling has been implicated in many human diseases including obesity, d
Externí odkaz:
https://doaj.org/article/af4e7102d52f4deba796f15bd5a6011e
Autor:
Weiqing Wang, Yi Xu, Lun Wang, Zhenzhen Zhu, Surita Aodeng, Hui Chen, Menghua Cai, Zhihao Huang, Jinbo Han, Lei Wang, Yuxi Lin, Yu Hu, Liangrui Zhou, Xiaowei Wang, Yang Zha, Weihong Jiang, Zhiqiang Gao, Wei He, Wei Lv, Jianmin Zhang
Publikováno v:
Nature Immunology. 23:1484-1494
The heterogeneous cellular microenvironment of human airway chronic inflammatory diseases, including chronic rhinosinusitis (CRS) and asthma, is still poorly understood. Here, we performed single-cell RNA sequencing (scRNA-seq) on the nasal mucosa of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768efc88acbbbb56f03a724d616607a9
https://doi.org/10.1038/s41590-022-01312-0
https://doi.org/10.1038/s41590-022-01312-0
Autor:
Jean Y.J. Wang, Helena L. Borges, Lars Eckmann, Michael E. Ramirez, Priya Sridevi, Anil Sadarangani, Rossana C. Soletti, Jinbo Han
PDF file - 2529K, S1 Similar levels of TUNEL-positive cells were observed in the splenic tissue sections from Rb+/+ and RbMI/MI mice at 24 hr after PBS (Veh) or TNF-α i.p. injection. Scale bar: 50 μm. **p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e4a527d0bf603d8601b2be7dc7f67b1
https://doi.org/10.1158/1541-7786.22509795
https://doi.org/10.1158/1541-7786.22509795
Autor:
Jean Y.J. Wang, Helena L. Borges, Lars Eckmann, Michael E. Ramirez, Priya Sridevi, Anil Sadarangani, Rossana C. Soletti, Jinbo Han
Tumor necrosis factor (TNF)-α promotes tumor development under chronic inflammation. Because TNF also activates caspase-8, selective inhibition of TNF-induced extrinsic apoptosis would be required for inflammation-associated tumor growth. In a mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8603c131ef1fa8068dbcc5396ea06415
https://doi.org/10.1158/1541-7786.c.6539400
https://doi.org/10.1158/1541-7786.c.6539400
Publikováno v:
International archives of allergy and immunology. 183(8)
Introduction: Eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP) exhibits a poorer prognosis than noneCRSwNP. The aim of this study was to analyze the potential of total immunoglobulin E (tIgE) and specific IgE (sIgE) levels in tissues f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbac8333d2ec9559743671306548571
https://pubmed.ncbi.nlm.nih.gov/35313318
https://pubmed.ncbi.nlm.nih.gov/35313318
Sarcomatoid carcinoma in the sinonasal cavity: A retrospective case series from a single institution
Publikováno v:
Auris, nasus, larynx. 49(5)
Sarcomatoid carcinoma (SC) is rare in the sinonasal cavity with poor prognosis. This study aimed to summarize the clinical characteristics, treatment and prognosis of patients with sinonasal SC from a single tertiary medical center.Retrospective revi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cf9b93b2fdf87a42a2d70b1f9ad6a3
https://pubmed.ncbi.nlm.nih.gov/35183394
https://pubmed.ncbi.nlm.nih.gov/35183394