Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jinah Yeo"'
Autor:
Seongryong Kim, Ji Hyang Jeon, Myeonghwan Kim, Yeji Lee, Yun-Ho Hwang, Myungsun Park, C. Han Li, Taeyoung Lee, Jung-Ah Lee, You-Me Kim, Dokeun Kim, Hyukjin Lee, You-Jin Kim, V. Narry Kim, Jong-Eun Park, Jinah Yeo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract mRNA vaccines against SARS-CoV-2 have revolutionized vaccine development, but their immunological mechanisms are not fully understood. Here, we investigate injection site responses of mRNA vaccines by generating a comprehensive single-cell t
Externí odkaz:
https://doaj.org/article/32015d5dd824456da3e3fddcd40f481a
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 200 (2021)
Tumors escape immune surveillance by inducing various immunosuppressive pathways, including the activation of inhibitory receptors on tumor-infiltrating T cells. While monoclonal antibodies (mAbs) blocking programmed cell death 1 (PD-1), programmed d
Externí odkaz:
https://doaj.org/article/e7f5f0ea03d646a6b197efce9ef2987f
Publikováno v:
Cell Reports, Vol 9, Iss 3, Pp 1061-1074 (2014)
TRBP functions as both a Dicer cofactor and a PKR inhibitor. However, the role of TRBP in microRNA (miRNA) biogenesis is controversial and its regulation of PKR in mitosis remains unexplored. Here, we generate TRBP knockout cells and find altered Dic
Externí odkaz:
https://doaj.org/article/9886e065332441e4b15aa8a32c9900ee
Autor:
Jaewon Song, Dong Wan Kim, Kwang Seok Ahn, Guhung Jung, Young-suk Lee, Young-Yoon Lee, Hyeshik Chang, Jinah Yeo, Jaechul Lim, Jenny J. Seo, Jong-Seo Kim, Soo-Jin Jung, V. Narry Kim, Jihye Yang
Publikováno v:
Nature Structural & Molecular Biology. 27:581-588
TENT4 enzymes generate 'mixed tails' of diverse nucleotides at 3' ends of RNAs via nontemplated nucleotide addition to protect messenger RNAs from deadenylation. Here we discover extensive mixed tailing in transcripts of hepatitis B virus (HBV) and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70cbf4ec8e71994dcb169e444f809942
https://doi.org/10.1038/s41594-020-0427-3
https://doi.org/10.1038/s41594-020-0427-3
Autor:
Jaewon Song, Minju Ha, Mihye Lee, Kwangseog Ahn, Jinah Yeo, V. Narry Kim, Young-suk Lee, Jaechul Lim, Hyeshik Chang, Dong Wan Kim
Publikováno v:
Science. 361:701-704
A tale of not-so-pure tails The poly(A) tail of mRNA has been thought to be a pure stretch of adenosine nucleotides with little informational content except for length. Lim et al. identified enzymes that can decorate poly(A) tails with non-A nucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ecef9c9bf4486560630f224e33ab49
https://doi.org/10.1126/science.aam5794
https://doi.org/10.1126/science.aam5794
Autor:
Dongwan, Kim, Young-Suk, Lee, Soo-Jin, Jung, Jinah, Yeo, Jenny J, Seo, Young-Yoon, Lee, Jaechul, Lim, Hyeshik, Chang, Jaewon, Song, Jihye, Yang, Jong-Seo, Kim, Guhung, Jung, Kwangseok, Ahn, V Narry, Kim
Publikováno v:
Nature structuralmolecular biology. 27(6)
TENT4 enzymes generate 'mixed tails' of diverse nucleotides at 3' ends of RNAs via nontemplated nucleotide addition to protect messenger RNAs from deadenylation. Here we discover extensive mixed tailing in transcripts of hepatitis B virus (HBV) and h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f54929b10a2e5c92715a4d9db551544e
https://pubmed.ncbi.nlm.nih.gov/32451488
https://pubmed.ncbi.nlm.nih.gov/32451488
Autor:
V. Narry Kim, Jinah Yeo
Publikováno v:
Nature structuralmolecular biology. 25(10)
RNA uridylation offers a basis for diverse post-transcriptional regulation. Two recent studies reveal new roles of uridylation in immune defense against viruses and retrotransposons.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ad74115bf26866d59f30fe632038fe
https://pubmed.ncbi.nlm.nih.gov/30242214
https://pubmed.ncbi.nlm.nih.gov/30242214
Autor:
Hee-Yeon Jeon, Kyu-Won Kim, Jaechul Lim, Hyunsook Lee, Hyunho Kim, Hyeshik Chang, Mihye Lee, V. Narry Kim, Jinah Yeo, Jiyeon Ohk, Jeong-gyun Kim, Hosung Jung, Hyunjoon Kim
Publikováno v:
Molecular cell. 70(1)
Summary During the maternal-to-zygotic transition (MZT), maternal RNAs are actively degraded and replaced by newly synthesized zygotic transcripts in a highly coordinated manner. However, it remains largely unknown how maternal mRNA decay is triggere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028d1ec1992b8cc061001d45ecd95cf4
https://pubmed.ncbi.nlm.nih.gov/29625039
https://pubmed.ncbi.nlm.nih.gov/29625039
Autor:
Jieon Lee, Soo-Ryoon Ryoo, Younghoon Lee, Jinah Yeo, Hongje Jang, Jung Hyun Lee, Young Kwan Kim, Vic Narry Kim, Dal-Hee Min, Hee-Kyung Na, Sang Woo Han
Publikováno v:
ACS Nano. 7:5882-5891
MicroRNA (miRNA) is an important small RNA which regulates diverse gene expression at the post-transcriptional level. miRNAs are considered as important biomarkers since abnormal expression of specific miRNAs is associated with many diseases includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe32dd8329a83a114be196f7c529f99
https://doi.org/10.1021/nn401183s
https://doi.org/10.1021/nn401183s
Publikováno v:
Molecular Cell. 43(6):1005-1014
Mammalian microRNAs (miRNAs) are highly stable in most cell types, and their decay mechanism remains largely unknown. Here we report that some miRNAs degrade rapidly upon the loss of cell adhesion. When cells are grown at low density or cells are det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c9ec666694db404cd0304d837fbade