Zobrazeno 1 - 10
of 448
pro vyhledávání: '"JinLin, Hou"'
Autor:
Henry L. Y. Chan, Yao Hu, Katharina Malinowsky, Kairat Madin, Konstantin Kroeniger, Jinlin Hou, Ashish Sharma
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Hepatocellular carcinoma (HCC) is often detected at advanced stages among patients with hepatitis B virus (HBV), underscoring the urgency for more precise surveillance tests. Here, we compare the clinical performance of the novel - GAAD (gen
Externí odkaz:
https://doaj.org/article/8d1da1cc8f7943d8b2b7a1cbefa5dabf
Autor:
Shuqin Gu, Libo Tang, Ling Guo, Chunxiu Zhong, Xin Fu, Guofu Ye, Shihong Zhong, Xiaoyi Li, Chunhua Wen, Yang Zhou, Jinling Wei, Haitao Chen, Nikolai Novikov, Simon P. Fletcher, M. Anthony Moody, Jinlin Hou, Yongyin Li
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
It is well established that humoral immunity targeting hepatitis B virus surface antigen (HBsAg) plays a critical role in viral clearance and clinical cure. However, the functional changes in HBsAg-specific B cells before and after achieving function
Externí odkaz:
https://doaj.org/article/f7d734b3c4d9471c9d5b1528dfa1a03e
Autor:
Liangxu Guo, Xin Hao, Lei Chen, Yunsong Qian, Chunying Wang, Xiaolong Liu, Xiaotang Fan, Guoqing Jiang, Dan Zheng, Pujun Gao, Honglian Bai, Chuanxin Wang, Yanlong Yu, Wencong Dai, Yanhang Gao, Xieer Liang, Jingfeng Liu, Jian Sun, Jie Tian, Hongyang Wang, Jinlin Hou, Rong Fan
Publikováno v:
EClinicalMedicine, Vol 74, Iss , Pp 102718- (2024)
Summary: Background: The diagnosis of hepatocellular carcinoma (HCC) often experiences latency, ultimately leading to unfavorable patient outcomes due to delayed therapeutic interventions. Our study is designed to develop and validate a model that em
Externí odkaz:
https://doaj.org/article/10e27e20538d4b3da9b6e11ae671b80a
Autor:
Wei Zhu, Zhiming Zhang, Jinzhang Chen, Xiaolan Chen, Lei Huang, Xiaoyong Zhang, Xuan Huang, Na Ma, Weikang Xu, Xuan Yi, Xinyu Lu, Xin Fu, Siwei Li, Guoheng Mo, Yiyue Wang, Guosheng Yuan, Mengya Zang, Qi Li, Xiaotao Jiang, Yajing He, Sha Wu, Yukai He, Yongyin Li, Jinlin Hou
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Strategies to improve T cell therapy efficacy in solid tumors such as hepatocellular carcinoma (HCC) are urgently needed. The common cytokine receptor γ chain (γc) family cytokines such as IL-2, IL-7, IL-15 and IL-21 play fundamental roles
Externí odkaz:
https://doaj.org/article/25b1939bfa5d4053805ba1ed9abc91df
Autor:
Jinlin Hou, Edward Gane, Rozalina Balabanska, Wenhong Zhang, Jiming Zhang, Tien Huey Lim, Qing Xie, Chau-Ting Yeh, Sheng-Shun Yang, Xieer Liang, Piyawat Komolmit, Apinya Leerapun, Zenghui Xue, Ethan Chen, Yuchen Zhang, Qiaoqiao Xie, Ting-Tsung Chang, Tsung-Hui Hu, Seng Gee Lim, Wan-Long Chuang, Barbara Leggett, Qingyan Bo, Xue Zhou, Miriam Triyatni, Wen Zhang, Man-Fung Yuen
Publikováno v:
Clinical and Molecular Hepatology, Vol 30, Iss 2, Pp 191-205 (2024)
Background/Aims Four-week treatment of linvencorvir (RO7049389) was generally safe and well tolerated, and showed anti-viral activity in chronic hepatitis B (CHB) patients. This study evaluated the efficacy, safety, and pharmacokinetics of 48-week tr
Externí odkaz:
https://doaj.org/article/aeead632d03142ec95bc4b04123f5c17
Autor:
Haixing Zhang, Xiaoran Li, Ziying Liu, Zimo Lin, Kuiyuan Huang, Yiran Wang, Yu Chen, Leyi Liao, Leyuan Wu, Zhanglian Xie, Jinlin Hou, Xiaoyong Zhang, Hongyan Liu
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Background Hypoxia contributes to cancer progression through various molecular mechanisms and hepatocellular carcinoma (HCC) is one of the most hypoxic malignancies. Hypoxia-inducible gene domain protein-1a (HIGD1A) is typically induced via
Externí odkaz:
https://doaj.org/article/60223844cbdb40a2980d13f7c7ca5cdf
Autor:
Hong You, Fu-Sheng Wang, Taisheng Li, Xiaoyuan Xu, Yameng Sun, Yuemin Nan, Guiqiang Wang, Jinlin Hou, Zhongping Duan, Lai Wei, Jidong Jia, Hui Zhuang, Chinese Society of Hepatology, Chinese Medical Association; Chinese Society of Infectious Diseases, Chinese Medical Association, Wei Zhao
Publikováno v:
Medicine, Vol 3, Iss 4, Pp 145-162 (2023)
Abstract. To facilitate the achieving of the goal of “eliminating viral hepatitis as a major public health threat by 2030” set by the World Health Organization, the Chinese Society of Hepatology together with the Chinese Society of Infectious Dis
Externí odkaz:
https://doaj.org/article/2e1b29e1c48d46d1a3b2293632e3a5ce
Publikováno v:
Diagnostic Pathology, Vol 18, Iss 1, Pp 1-6 (2023)
Abstract SMARCA4-deficient undifferentiated uterine sarcoma (SDUS) is a highly invasive single-gene malignant tumor caused by mutations in the SMARCA4 gene. SDUS has a poor prognosis, with no established treatment strategy at present. Further, there
Externí odkaz:
https://doaj.org/article/051f7060c1124d8cb52c3635f28e71a7
Autor:
Sheng Shen, Ran Yan, Zhanglian Xie, Xiaoyang Yu, Hongyan Liang, Qiuhong You, Hu Zhang, Jinlin Hou, Xiaoyong Zhang, Yuanjie Liu, Jian Sun, Haitao Guo
Publikováno v:
Viruses, Vol 16, Iss 6, p 890 (2024)
Tripartite motif (TRIM) proteins, comprising a family of over 100 members with conserved motifs, exhibit diverse biological functions. Several TRIM proteins influence viral infections through direct antiviral mechanisms or by regulating host antivira
Externí odkaz:
https://doaj.org/article/256b3eafdc7d4d658498365159f415d5
Autor:
Yangqing Zhan, Zhengshi Lin, Jingyi Liang, Ruilin Sun, Yueping Li, Bingliang Lin, Fangqi Ge, Ling Lin, Hongzhou Lu, Liang Su, Tianxin Xiang, Hongqiu Pan, Chaolin Huang, Ying Deng, Furong Wang, Ruhong Xu, Dexiong Chen, Ping Zhang, Jianlin Tong, Xifu Wang, Qingwei Meng, Zhigang Zheng, Shuqiang Ou, Xiaoyun Guo, Herui Yao, Tao Yu, Weiyang Li, Yu Zhang, Mei Jiang, Zhonghao Fang, Yudi Song, Ruifeng Chen, Jincan Luo, Changyuan Kang, Shiwei Liang, Haijun Li, Jingping Zheng, Nanshan Zhong, Zifeng Yang, Huang Yanming, M.M, Dong Haiping, M.D., Jinlin Hou, M.M, Shao Lei, M.D., Li Xiaoguang, M.D., Gao Yan, M.M.
Publikováno v:
EClinicalMedicine, Vol 67, Iss , Pp 102359- (2024)
Summary: Background: Leritrelvir is a novel α-ketoamide based peptidomimetic inhibitor of SARS-CoV-2 main protease. A preclinical study has demonstrated leritrelvir poses similar antiviral activities towards different SARS-CoV-2 variants compared wi
Externí odkaz:
https://doaj.org/article/47dbfffb279a4d67b276d3a4042f438c