Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Jin-hua Gu"'
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 6, Pp 1221-1232 (2024)
Alzheimer’s disease is characterized by two major neuropathological hallmarks—the extracellular β-amyloid plaques and intracellular neurofibrillary tangles consisting of aggregated and hyperphosphorylated Tau protein. Recent studies suggest that
Externí odkaz:
https://doaj.org/article/6fef2a4444084826a17ec59fd7d262a7
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Protein glycosylation is an extensively studied field, with the most studied forms being oxygen or nitrogen-linked N-acetylglucosamine (O-GlcNAc or N-GlcNAc) glycosylation. Particular residues on proteins are targeted by O-GlcNAcylation, which is amo
Externí odkaz:
https://doaj.org/article/d8bf37facfd8408490d8152c68137da3
Autor:
Yuan-yuan Wei, Hui-ru Wang, Yi-meng Fan, Jin-hua Gu, Xiu-ying Zhang, Xu-hao Gong, Zhi-hui Hao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 251, Iss , Pp 114527- (2023)
The aims of this study were to evaluated the effect and underlying mechanism of Gandankang (GDK) aqueous extract in alleviating the acute liver injury induced by carbon tetrachloride (CCl4) in vivo and in vitro. Mice were divided into 5 groups (n = 8
Externí odkaz:
https://doaj.org/article/22c30f3beac3430999b02b5f462db31a
Autor:
Yuan-yuan Wei, Yan-nan Zhang, Huiru Wang, Yu Ga, Yimeng Fan, Qingtao Wang, Jin-hua Gu, Xiu-ying Zhang, Xu-hao Gong, Zhi-hui Hao
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 245, Iss , Pp 114118- (2022)
Mori fructus aqueous extracts (MFAEs) have been used as a traditional Chinese medicine for thousands of years with the function of strengthening the liver and tonifying the kidney. However, its inner mechanism to alleviative renal injury is unclear.
Externí odkaz:
https://doaj.org/article/454800c5c396489dac238c993599cfaf
Autor:
Yake Liu, Wenfeng Zhu, Dalong Ni, Zihua Zhou, Jin-hua Gu, Weinan Zhang, Huanjian Sun, Fan Liu
Publikováno v:
Journal of Nanobiotechnology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract As a main element in the hard metal industry, cobalt is one of the major components of human metal implants. Cobalt-containing implants, especially joint prostheses used for artificial joint replacement, can be corroded due to the complex ph
Externí odkaz:
https://doaj.org/article/bc3f483bec7b4cf18203a601e9ec2fc1
Autor:
Ruochen Cong, Linlin Sun, Jushun Yang, Hengxiang Cui, Xin Ji, Jing Zhu, Jin-hua Gu, Bosheng He
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss , Pp 111477- (2021)
Protein O-GlcNAcylation is a dynamic post-translational protein modification that regulates fundamental cellular functions in both normal physiology and diseases. The levels of protein O-GlcNAcylation are determined by flux of the hexosamine biosynth
Externí odkaz:
https://doaj.org/article/8b36be5904664b5c871a52f410e4e833
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Background/Aim: Music-based therapy plays a role in central nervous system diseases. We aimed to explore the effect of different doses and durations of music therapy on motor function recovery after stroke and the underlying molecular mechanisms.Meth
Externí odkaz:
https://doaj.org/article/79e1557817b347b5b009d1e73633ad0f
Autor:
Hengchang Li, Chun-ling Dai, Jin-Hua Gu, Shengwei Peng, Jian Li, Qian Yu, Khalid Iqbal, Fei Liu, Cheng-Xin Gong
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Children, after multiple exposures to general anesthesia, appear to be at an increased risk of developing learning disabilities. Almost all general anesthetics—including sevoflurane, which is commonly used for children—are potentially neurotoxic
Externí odkaz:
https://doaj.org/article/7aff22868bc84316b96e59d05baea62c
Autor:
Yaohui Ni, Kefu Cai, Yujie Hu, Chuan-hui Wang, Yuanyuan Zhang, Hua Huang, Xing Su, Jin-hua Gu
Publikováno v:
Stem Cells International, Vol 2018 (2018)
Delayed administration of kallikrein after cerebral infarction can improve neurological function. However, the appropriate kallkrein treatment time after ischemic stroke has not been illuminated. In this study, we compared the long-term outcome among
Externí odkaz:
https://doaj.org/article/2b07cde5f7ea400b85199ab024af15aa
Autor:
Hai-Dong Xu, Dan Wu, Jin-Hua Gu, Jian-Bin Ge, Jun-Chao Wu, Rong Han, Zhong-Qin Liang, Zheng-Hong Qin
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63232 (2013)
Autophagy can be induced under nutrition stress conditions. Bcl-2 is a pro-survival protein which inhibits apoptosis and autophagy. However, the role of Bcl-2 in autophagy regulation and cell survival under nutrition deprivation has not been fully un
Externí odkaz:
https://doaj.org/article/ae68670055334b23a7ed4834a3be120f