Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jin-bao Zhang"'
Autor:
Jin-Bao Zhang, Xiao-Jie Wan, Wen-Xiang Duan, Xue-Qin Dai, Dong Xia, Xiang Fu, Li-Fang Hu, Fen Wang, Chun-Feng Liu
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Circadian disruption often arises prior to the onset of typical motor deficits in patients with Parkinson’s disease (PD). It remains unclear whether such a prevalent non-motor manifestation would contribute to the progression of PD. Diffus
Externí odkaz:
https://doaj.org/article/0faca6adacbe480bb8b3e5e814090444
Autor:
Kai-Jie He, Jin-Bao Zhang, Jun-Yi Liu, Feng-Lun Zhao, Xiao-Yu Yao, Yu-Ting Tang, Jin-Ru Zhang, Xiao-Yu Cheng, Li-Fang Hu, Fen Wang, Chun-Feng Liu
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108130- (2023)
Summary: Parkinson’s disease (PD) is characterized by the irreversible loss of dopaminergic neurons and the accumulation of α-synuclein in Lewy bodies. The oligomeric α-synuclein (O-αS) is the most toxic form of α-synuclein species, and it has
Externí odkaz:
https://doaj.org/article/dff66759520d4563a10963fed7afb949
Advances in intranasal application of stem cells in the treatment of central nervous system diseases
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Stem cells are characterized by their self-renewal and multipotency and have great potential in the therapy of various disorders. However, the blood–brain barrier (BBB) limits the application of stem cells in the therapy of neurological di
Externí odkaz:
https://doaj.org/article/4418c7a117064746bdf0cee5689403a5
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Neurodegenerative disease (NDD), including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which leads to the decline of motor and/or cognitive function. Currently,
Externí odkaz:
https://doaj.org/article/b2a7a0a4831d4e3ab56c8dd977741e9b
Autor:
Michal Pruski, Ling Hu, Cuiping Yang, Yubing Wang, Jin-Bao Zhang, Lei Zhang, Ying Huang, Ann M. Rajnicek, David St Clair, Colin D. McCaig, Bing Lang, Yu-Qiang Ding
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
The cilium of a cell translates varied extracellular cues into intracellular signals that control embryonic development and organ function. The dynamic maintenance of ciliary structure and function requires balanced bidirectional cargo transport invo
Externí odkaz:
https://doaj.org/article/53cbbde667cc4caca81000127e02317b
Autor:
Chao Liu, Hou-ning Zhou, Rui-rui Zhang, Xin-kun Wang, Sheng-wen He, Jin-bao Zhang, Xu Guo, Qing Wang, Jin-yue Sun
Publikováno v:
Journal of Functional Foods, Vol 61, Iss , Pp - (2019)
Hyperuricemia is a key risk factor for kidney disease. Geniposide possesses various pharmacological activities, however, to our knowledge, no previous work investigated the therapeutic effect of geniposide on urate nephropathy. The present study esta
Externí odkaz:
https://doaj.org/article/2d935026be0f4c53b24139a4635dcffe
Autor:
Jin-Bao Zhang, Shenghai Chang, Pan Xu, Miao Miao, Hangjun Wu, Youyi Zhang, Tongtong Zhang, Han Wang, Jilin Zhang, Chun Xie, Nan Song, Cheng Luo, Xing Zhang, Shujia Zhu
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3582-3590.e4 (2018)
Summary: N-methyl-D-aspartate (NMDA) receptors are critical for synaptic development and plasticity. While glutamate is the primary agonist, protons can modulate NMDA receptor activity at synapses during vesicle exocytosis by mechanisms that are unkn
Externí odkaz:
https://doaj.org/article/a565a9a6302a48e2aa920e3aff00d2fb
Publikováno v:
Journal of Integrative Agriculture, Vol 11, Iss 4, Pp 537-544 (2012)
The joint analysis of the mixed genetic model of major gene and polygene was conducted to study the inheritance of cryotolerance in cotton during the overwintering period. H077 (G. hirsutum L., weak cryotolerance) and H113 (G. barbadence L., strong c
Externí odkaz:
https://doaj.org/article/66ae4fcc139e459b98e54c77dc6f4299
Autor:
Chu-Wen Fang, Bai-Fu Wang, Jie-Shan Lin, Heng-Jie Jiang, Jin-Bao Zhang, Mon-I. Yen, Sheng-Xian Huang, Jun-Ji Chen, Hong-ren Shi, Jian-Xiang Zhang
Publikováno v:
Urological Science, Vol 26, Iss 4, p 294 (2015)
Externí odkaz:
https://doaj.org/article/8788a120f2d5477abf2fbb09c69b8ca3
Autor:
Cheng-Jie Mao, Fen Wang, Chao Ren, Jin-Bao Zhang, Chun-Feng Liu, Jing Chen, Dan Li, Hua Hu, Kai-Jie He, Li-Guo Dong
Publikováno v:
Journal of Parkinson's Disease. 12:295-314
Background: Previous investigations have suggested that decreased expression of glutamate transporter-1 (GLT-1) is involved in glutamate excitotoxicity and contribute to the development of Parkinson’s disease (PD), GLT-1 is decreased in animal mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49c1b04a7db328965b6bd3f30570f1b
https://doi.org/10.3233/jpd-212640
https://doi.org/10.3233/jpd-212640