Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jin-Yuan Lyu"'
Autor:
Hu-Lin Jiang, Jian-Bin Qiao, Peng-Fei Cui, Shunai Che, Jia-Liang Zhang, Lei Xing, Tuo jin, Jia-Hui Gong, Jin-Yuan Lyu, Yu-Jing He
Publikováno v:
RSC Advances. 6:65854-65865
The co-delivery of platinum(IV) prodrugs and nucleic acids has emerged as a new modality for cancer therapy. However, as a result of the different molecular properties of nucleic acids and platinum(IV) prodrugs, the co-delivery of platinum(IV) prodru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::327b7d47f93183d75dd478eb03c36be0
https://doi.org/10.1039/c6ra16435h
https://doi.org/10.1039/c6ra16435h
Autor:
Peng-Fei Cui, Hu-Lin Jiang, Jian-Bin Qiao, Rong-Lin Xie, Feng-Zhen Wang, Bing-Feng Zhang, Mei Zhang, Jia-Liang Zhang, Lei Xing, Yu-Jing He, Jin-Yuan Lyu, Baoan Chen
Publikováno v:
Biomaterials. 61:178-189
The mitochondria-mediated apoptosis pathway is an effective option for cancer therapy due to the presence of cell-suicide weapons in mitochondria. However, anti-apoptotic proteins that are over-expressed in the mitochondria of many malignant tumors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b494074b1043b64b57123c028f8896cd
https://doi.org/10.1016/j.biomaterials.2015.05.027
https://doi.org/10.1016/j.biomaterials.2015.05.027
Autor:
Liu-Qing Gu, Lei Xing, Yu Liu, Xiaojun Xu, Jian-Bin Qiao, Peng-Fei Cui, Jin-Yuan Lyu, Hu-Lin Jiang, Minjie Sun, Yu-Jing He, Yue Yang, Tian-Qi Zhang, Jin-Jian Lu
Publikováno v:
Chemical communications (Cambridge, England). 53(62)
We have developed mitochondria-targeted self-assembled nanoparticles (NPs) based on amphiphilic triphenylphosphine–quercetin (TPP–Que) conjugates, which were further modified by poly(ethylene glycol) via a pH-responsive coordination bond to form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5656732ba48a64af8ebb6cc54bb6c222
https://pubmed.ncbi.nlm.nih.gov/28736782
https://pubmed.ncbi.nlm.nih.gov/28736782
Autor:
Peng-Fei Cui, Yu-Xin Zhou, Na Lu, Yu-Jing He, Yong Zhu, Lei Xing, Jin-Yuan Lyu, Hu-Lin Jiang, Jian-Bin Qiao, Mei Zhang, Jia-Liang Zhang, Cheng-Qiong Luo
Publikováno v:
Biomaterials. 113
A novel biomimetic drug delivery system (BDDS) inspired by the pH-dependent ferric ion-transport and release manner of transferrin (Tf) was developed for combating multidrug-resistant breast cancer. Tf-inspired carrier was synthesized by modifying bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aba1ae7c3e64f5b4d83bc11cbb965f3
https://pubmed.ncbi.nlm.nih.gov/27842254
https://pubmed.ncbi.nlm.nih.gov/27842254
Autor:
Peng-Fei Cui, Cheng-Qiong Luo, Shunai Che, Jian-Bin Qiao, Tuo jin, Yu-Jing He, Lei Xing, Mei Zhang, Jia-Hui Gong, Jin-Yuan Lyu, Hu-Lin Jiang, Jia-Liang Zhang
Publikováno v:
International journal of pharmaceutics. 513(1-2)
This report demonstrated a one-step assembly for co-delivering chemotherapeutics and therapeutic nucleic acids, constructed by integrating drug molecules into a nucleic acid condensing polymeric prodrug through degradable linkages. Demethylcantharate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fcf4feb97260fed0bd3a9cf93cd8e11
https://pubmed.ncbi.nlm.nih.gov/27682215
https://pubmed.ncbi.nlm.nih.gov/27682215
Autor:
Hu-Lin Jiang, Peng-Fei Cui, Yu-Jing He, Liang Jin, Jian Bin Qiao, Cheng-Qiong Luo, Mei Zhang, Jia-Liang Zhang, Lei Xing, Jin-Yuan Lyu
Publikováno v:
International journal of pharmaceutics. 506(1-2)
Polyamine content, which is associated with tumor growth, can be regulated by ornithine decarboxylase (ODC) and S-adenosyl methionine decarboxylase (SAMDC), two key enzymes in polyamine biosynthesis. Here we aim to develop a pH-responsive cationic po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56d38eb3c38e16aeb491d780752646f
https://pubmed.ncbi.nlm.nih.gov/27102990
https://pubmed.ncbi.nlm.nih.gov/27102990
Autor:
Cheng-Qiong Luo, Peng-Fei Cui, Lei Xing, Hu-Lin Jiang, Jian-Bin Qiao, You-Kyoung Kim, Yu-Jing He, Mei Zhang, Jia-Liang Zhang, Jin-Yuan Lyu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 6, Iss 4, Pp 336-343 (2016)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Biodegradable polyamines have long been studied as potential recombinant viral gene vectors. Spermine (SPE) is an endogenous tetra-amine with excellent biocompatibility yet poor gene condensation capacity. We have previously synthesized a polyspermin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d644415207da4e86ebd73b6796d0cd56