Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Jin-Wu Tsai"'
Autor:
Tyng-An Zhou, Hsuan-Po Hsu, Yueh-Hua Tu, Hui-Kuei Cheng, Chih-Yu Lin, Nien-Jung Chen, Jin-Wu Tsai, Ellen A Robey, Hsuan-Cheng Huang, Chia-Lin Hsu, Ivan L Dzhagalov
Publikováno v:
eLife, Vol 11 (2022)
Tissue-resident macrophages are essential to protect from pathogen invasion and maintain organ homeostasis. The ability of thymic macrophages to engulf apoptotic thymocytes is well appreciated, but little is known about their ontogeny, maintenance, a
Externí odkaz:
https://doaj.org/article/e2be2a7d17c844db955442ecde1ea243
Autor:
Huan-Yun Chen, Chia-Lang Hsu, Han-Yi Lin, Yung-Feng Lin, Shih-Feng Tsai, Yu-Jung Ho, Ye-Ru Li, Jin-Wu Tsai, Shu-Chun Teng, Chin-Hsien Lin
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-17 (2021)
Abstract Background Heterozygous pathogenic variants in STUB1 are implicated in autosomal dominant spinocerebellar ataxia type 48 (SCA48), which is a rare familial ataxia disorder. We investigated the clinical, genetic and functional characteristics
Externí odkaz:
https://doaj.org/article/e1e098472bbd45b8a5e7d3b551df8c1e
Autor:
Chin-Ju Hu, Ying-Chang Lu, Yi-Hsiu Tsai, Haw-Yuan Cheng, Hiroki Takeda, Chun-Ying Huang, Ru Xiao, Chuan-Jen Hsu, Jin-Wu Tsai, Luk H. Vandenberghe, Chen-Chi Wu, Yen-Fu Cheng
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 493-500 (2020)
Sensorineural hearing loss is one of the most common sensory disorders worldwide. Recent advances in vector design have paved the way for investigations into the use of adeno-associated vectors (AAVs) for hearing disorder gene therapy. Numerous AAV s
Externí odkaz:
https://doaj.org/article/3d99ac29290f4535b5ffc081bedfe891
Autor:
Meng-Han Tsai, Haw-Yuan Cheng, Fang-Shin Nian, Chen Liu, Nian-Hsin Chao, Kuo-Liang Chiang, Shu-Fang Chen, Jin-Wu Tsai
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract During brain development, the nucleus of migrating neurons follows the centrosome and translocates into the leading process. Defects in these migratory events, which affect neuronal migration, cause lissencephaly and other neurodevelopmental
Externí odkaz:
https://doaj.org/article/5df5849e9cd34b418a022b70785d3207
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Kinesin-binding protein (KBP; KIF1BP; KIAA1279) functions as a regulator for a subset of kinesins, many of which play important roles in neural development. Previous studies have shown that KBP is expressed in nearly all tissue with cytoplasmic local
Externí odkaz:
https://doaj.org/article/64cb0425036741f6ab9bcd41c1bb5a58
Autor:
I-Ling Lu, Chien Chen, Chien-Yi Tung, Hsin-Hung Chen, Jia-Ping Pan, Chia-Hsiang Chang, Jia-Shing Cheng, Yi-An Chen, Chun-Hung Wang, Chia-Wei Huang, Yi-Ning Kang, Hsin-Yun Chang, Lei-Li Li, Kai-Ping Chang, Yang-Hsin Shih, Chi-Hung Lin, Shang-Yeong Kwan, Jin-Wu Tsai
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Cortical malformations have a variety of causes. Here the authors use transposon mutagenesis to insert mutations into neural stem cells in the developing mouse cortex to screen for new candidate genes for cortical malformation, and validate some targ
Externí odkaz:
https://doaj.org/article/c05ccfd211e247a681f50e19151a3d9c
Autor:
Elisa Savino, Fabrizia Claudia Guarnieri, Jin-Wu Tsai, Anna Corradi, Fabio Benfenati, Flavia Valtorta
Publikováno v:
Cells, Vol 10, Iss 10, p 2666 (2021)
Mutations in the PRRT2 gene are the main cause for a group of paroxysmal neurological diseases including paroxysmal kinesigenic dyskinesia, episodic ataxia, benign familial infantile seizures, and hemiplegic migraine. In the mature central nervous sy
Externí odkaz:
https://doaj.org/article/5c80e2e8e6df4d6c98ef9fd1d51b40d6
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Transthyretin amyloidosis (ATTR amyloidosis) is a fatal systemic disease caused by amyloid deposits of misfolded transthyretin, leading to familial amyloid polyneuropathy and/or cardiomyopathy, or a rare oculoleptomeningeal amyloidosis. A good model
Externí odkaz:
https://doaj.org/article/49f484de64394bc5ae95880dad011bb3
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
During neocortical development, newborn neurons migrate along radial fibers from the germinal ventricular zone (VZ) toward the cortical plate (CP) to populate the cerebral cortex. This radial migration requires adhesion activities between neurons and
Externí odkaz:
https://doaj.org/article/3be53fa7abe34d49b2057e183d753cc8
Autor:
Chu-Yuan Chang, Min-Zong Liang, Ching-Chih Wu, Pei-Yuan Huang, Hong-I Chen, Shaw-Fang Yet, Jin-Wu Tsai, Cheng-Fu Kao, Linyi Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1463 (2020)
The treatment of traumatic brain injury (TBI) remains a challenge due to limited knowledge about the mechanisms underlying neuronal regeneration. This current study compared the expression of WNT genes during regeneration of injured cortical neurons.
Externí odkaz:
https://doaj.org/article/65ac60baaf09406995c845edfa38883d