Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Jin-Wu Nam"'
Autor:
Seo-Won Choi, Jin-Wu Nam
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 6, Pp 1281-1292 (2024)
Abstract Circular RNAs are an unusual class of single-stranded RNAs whose ends are covalently linked via back-splicing. Due to their versatility, the need to express circular RNAs in vivo and in vitro has increased. Efforts have been made to efficien
Externí odkaz:
https://doaj.org/article/edef67550a864e0ea0580991a3ff476f
Autor:
Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam
Publikováno v:
eLife, Vol 12 (2024)
The α-arrestins form a large family of evolutionally conserved modulators that control diverse signaling pathways, including both G-protein-coupled receptor (GPCR)-mediated and non-GPCR-mediated pathways, across eukaryotes. However, unlike β-arrest
Externí odkaz:
https://doaj.org/article/26a1255e38244e79aa6faf01633eb0e2
Autor:
Seong-geun Moon, Ansun Jeong, Yunji Han, Jin-Wu Nam, Mi Kyung Kim, Inah Kim, Yu-Mi Kim, Boyoung Park
Publikováno v:
Journal of Preventive Medicine and Public Health, Vol 56, Iss 1, Pp 1-11 (2023)
In 1945, atomic bombs were dropped on Hiroshima and Nagasaki. Approximately 70 000 Koreans are estimated to have been exposed to radiation from atomic bombs at that time. After Korea’s Liberation Day, approximately 23 000 of these people returned t
Externí odkaz:
https://doaj.org/article/c54d991a927241958c34fb07f1cdf5c8
Autor:
Sukjun Kim, Soyoung Kim, Hee Ryung Chang, Doyeon Kim, Junehee Park, Narae Son, Joori Park, Minhyuk Yoon, Gwangung Chae, Young-Kook Kim, V. Narry Kim, Yoon Ki Kim, Jin-Wu Nam, Chanseok Shin, Daehyun Baek
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
miRNAs are loaded into Argonaute protein and repress complementary mRNA targets. Here the authors show the unappreciated role of RNA binding proteins for efficient miRNA targeting and expand the current understanding of miRNA targeting.
Externí odkaz:
https://doaj.org/article/fa80ba4bd3e24c5eae00608527853f85
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-13 (2021)
Abstract Immune class in hepatocellular carcinoma (HCC) has been shown to possess immunogenic power; however, how preestablished immune landscapes in premalignant and early HCC stages impact the clinical outcomes of HCC patients remains unexplored. W
Externí odkaz:
https://doaj.org/article/be2d57dbb8d94979ae11c1777d38e809
Autor:
Bumsik Cho, Sang-Ho Yoon, Daewon Lee, Ferdinand Koranteng, Sudhir Gopal Tattikota, Nuri Cha, Mingyu Shin, Hobin Do, Yanhui Hu, Sue Young Oh, Daehan Lee, A. Vipin Menon, Seok Jun Moon, Norbert Perrimon, Jin-Wu Nam, Jiwon Shim
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
How the Drosophila lymph gland hemocytes develop and are regulated at a single-cell level is unclear. Here, the authors use single-cell RNA sequencing to show heterogeneity of developing hemocytes in the lymph gland and how they react to wasp infesta
Externí odkaz:
https://doaj.org/article/a217d9fbf42943298b9152638532fa93
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 814-820 (2020)
The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-Cas systems, including dead Cas9 (dCas9), Cas9, and Cas12a, have revolutionized genome engineering in mammalian somatic cells. Although computational tools that assess the target
Externí odkaz:
https://doaj.org/article/d55238c9f88946be84b657511263f0f7
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
UPF1 mediates the decay of target mRNA in a 3′ untranslated region (UTR)-length-dependent manner. Here the authors reveal that the 3′UTR-length-dependent regulation of UPF1-dependent mRNA decay occurs through EJC-independent but miRNA-dependent r
Externí odkaz:
https://doaj.org/article/aeabc36501bf4d86b4a07be8fc7af2cd
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Splenic long-lived plasma cells are abnormally numerous and deleterious in systemic autoimmune diseases, yet how they accumulate remains poorly understood. We demonstrate here that a pathological role of spleen-derived CD11b+Gr-1+ myeloid cells (SDMC
Externí odkaz:
https://doaj.org/article/063a5337b889454fa6bd5f813e765b4e
Autor:
Sudhir Gopal Tattikota, Bumsik Cho, Yifang Liu, Yanhui Hu, Victor Barrera, Michael J Steinbaugh, Sang-Ho Yoon, Aram Comjean, Fangge Li, Franz Dervis, Ruei-Jiun Hung, Jin-Wu Nam, Shannan Ho Sui, Jiwon Shim, Norbert Perrimon
Publikováno v:
eLife, Vol 9 (2020)
Drosophila blood cells, called hemocytes, are classified into plasmatocytes, crystal cells, and lamellocytes based on the expression of a few marker genes and cell morphologies, which are inadequate to classify the complete hemocyte repertoire. Here,
Externí odkaz:
https://doaj.org/article/d567f0c434cc4169a01a912c8ae544a0