Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Jin-Sil Park"'
Autor:
Eunkyeong Jang, ChangYeon Kim, Jeonghyun Noh, Hansol Yi, Sungsin Jo, Jin-Sil Park, Woochang Hwang, Ji-Young Cha, Mi-La Cho, Tae-Hwan Kim, Jeehee Youn
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114878- (2024)
Summary: The transcription repressor Bach2 plays a crucial role in shaping humoral immunity, but its cell-autonomous function remains elusive. Here, we reveal the mechanism by which Bach2 regulates effector cell maturation in peripheral B cells. In r
Externí odkaz:
https://doaj.org/article/6a860a8f9487444a8b232efaedba224c
Autor:
Jin-Sil Park, Chongtae Kim, JeongWon Choi, Ha Yeon Jeong, Young-Mee Moon, Hoin Kang, Eun Kyung Lee, Mi-La Cho, Sung-Hwan Park
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-11 (2024)
Abstract Background MicroRNA (miRNA)-21-5p participates in various biological processes, including cancer and autoimmune diseases. However, its role in the development of fibrosis in the in vivo model of systemic sclerosis (SSc) has not been reported
Externí odkaz:
https://doaj.org/article/fd76fdced2a247f194055a0f244ed530
Autor:
Ha Yeon Jeong, Jin-Sil Park, Jin Seok Woo, Kun Hee Lee, Jeong Won Choi, Hye Yeon Kang, Hyun Sik Na, Yeon Su Lee, In Gyu Um, Sung-Hwan Park, Mi-La Cho
Publikováno v:
Journal of Inflammation, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Background Coronavirus disease 2019 (COVID-19) induces a dysfunctional immune response, inflammation, autoantibody production, and coagulopathy, which are symptoms that bear resemblance to those of autoimmune diseases, including systemic scl
Externí odkaz:
https://doaj.org/article/813a12aaaa2046efbdc1121831fd2fcc
Autor:
Jin Seok Woo, Sun-Hee Hwang, SeungCheon Yang, Kun Hee Lee, Yeon Su Lee, Jeong Won Choi, Jin-Sil Park, JooYeon Jhun, Sung-Hwan Park, Mi-La Cho
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Sjögren’s syndrome (SS) is an autoimmune disease characterized by inflammation of the exocrine gland. An imbalance of gut microbiota has been linked to SS. However, the molecular mechanism is unclear. We investigated the effect
Externí odkaz:
https://doaj.org/article/fe462b290db14f55be88653c72b5de35
Autor:
Jin-Sil Park, Seung Cheon Yang, Ha Yeon Jeong, Seon-Young Lee, Jun-Geol Ryu, Jeong Won Choi, Hye Yeon Kang, Sung-Min Kim, Sun-Hee Hwang, Mi-La Cho, Sung-Hwan Park
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-18 (2022)
Abstract Background EC-18, a synthetic monoacetyldiaglyceride, exhibits protective effects against lung inflammation, allergic asthma, and abdominal sepsis. However, there have been no investigations to determine whether EC-18 has preventive potentia
Externí odkaz:
https://doaj.org/article/a5f714d1c41043b984c6add7660bf78b
Autor:
Jin-Sil Park, Donghyun Lee, SeungCheon Yang, Ha Yeon Jeong, Hyun Sik Na, Keun-Hyung Cho, JeongWon Choi, Heebeom Koo, Mi-La Cho, Sung-Hwan Park
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Rheumatoid arthritis (RA) is a progressive systemic autoimmune disease that is characterized by infiltration of inflammatory cells into the hyperplastic synovial tissue, resulting in subsequent destruction of adjacent articular ca
Externí odkaz:
https://doaj.org/article/02cc582e476549a680c2eee1a19aff57
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280601 (2023)
Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized by progressive joint destruction. Green-lipped mussel (GLM) has chondro-modulatory and anti-inflammatory properties, but the mechanism underlying the effect of GLM on RA is un
Externí odkaz:
https://doaj.org/article/6d07c29edbb5424594d325c865da3664
Autor:
Sun-Hee Hwang, Jin-Sil Park, SeungCheon Yang, Kyung-Ah Jung, JeongWon Choi, Seung-Ki Kwok, Sung-Hwan Park, Mi-La Cho
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-9 (2020)
Abstract Background Sjögren’s syndrome (SS) is an autoimmune disease mediated by lymphocytic infiltration into exocrine glands, resulting in progressive lacrimal and salivary destruction and dysfunctional glandular secretion. Metabolic syndrome in
Externí odkaz:
https://doaj.org/article/caf46661e6ae4bf687440d3ee2a3cf0f
Autor:
Sun-Hee Hwang, Jin Seok Woo, Jeonghyeon Moon, SeungCheon Yang, Jin-Sil Park, JaeSeon Lee, JeongWon Choi, Kun Hee Lee, Seung-Ki Kwok, Sung-Hwan Park, Mi-La Cho
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Previous studies have evaluated the roles of T and B cells in the pathogenesis of Sjögren’s syndrome (SS); however, their relationships with age-dependent and metabolic abnormalities remain unclear. We examined the impacts of changes associated wi
Externí odkaz:
https://doaj.org/article/446ce04b01fb4a4189e807785a8a6da2
Autor:
SeungCheon Yang, Jin-Sil Park, Sun-Hee Hwang, Keun-Hyung Cho, Hyun Sik Na, JeongWon Choi, Jooyeon Jhun, Seung-Jun Kim, Bo-In Lee, Sung-Hwan Park, Mi-La Cho
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Small heterodimer partner interacting leucine zipper protein (SMILE) is an orphan nuclear receptor and a member of the bZIP family of proteins. We investigated the mechanism by which SMILE suppressed the development of inflammatory bowel disease (IBD
Externí odkaz:
https://doaj.org/article/d2a5017fdf034264be2e743c689acedc