Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jin-Shuai Lan"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 776-788 (2017)
A novel family of cinnamic acid derivatives has been developed to be multifunctional cholinesterase inhibitors against AD by fusing N-benzyl pyridinium moiety and different substituted cinnamic acids. In vitro studies showed that most compounds were
Externí odkaz:
https://doaj.org/article/2e07a5c5777842d59d6f8db9b65181bf
Autor:
Yan-Hong Qin, Xiao-Yi Jiang, Yuan-Fang Que, Jing-Yi Gu, Tong Wu, Ayinazhaer Aihemaiti, Ke-Xin Shi, Wen-Yu Kang, Bi-Ying Hu, Jin-Shuai Lan, Yue Ding, Tong Zhang
Publikováno v:
Molecules, Vol 24, Iss 21, p 4011 (2019)
Based upon the intramolecular charge transfer (ICT) mechanism, a novel ratiometric fluorescent probe EB was developed to detect SO32−/HSO3−. The probe displayed both colorimetric and ratiometric responses toward SO32−/HSO3−. It displayed a qu
Externí odkaz:
https://doaj.org/article/f949bea2ca524c05b5b04b4e58f7b172
Publikováno v:
Molecules, Vol 23, Iss 9, p 2146 (2018)
A series of novel alkyl amine-substituted icariside II (ICA II) derivatives were synthesized by Mannich reactions at the 6-C position (compounds 4a–d) and changing the carbon chain length at the 7-OH position (compounds 7a–h), and their in vitro
Externí odkaz:
https://doaj.org/article/2119cfebdd594ae7905fbe76461f7e28
Autor:
Rui-Feng Zeng, Jin-Shuai Lan, Xiao-Die Li, Hui-Fen Liang, Yan Liao, Ying-Jie Lu, Tong Zhang, Yue Ding
Publikováno v:
Molecules, Vol 22, Iss 10, p 1618 (2017)
A new coumarin-based fluorescent probe, containing an allylic esters group, has been designed and synthesized for sensing cysteine in physiological pH. In this fluorescent probe, the coumarin was applied as the fluorophore and an allylic esters group
Externí odkaz:
https://doaj.org/article/58bf6c67976f43beaeaf91a52370bafc
Autor:
Tong Zhang, Li Liu, Rui-Feng Zeng, Yan-Hong Qin, Yun Liu, Xiao-Yi Jiang, Yue Ding, Ayinazhaer Aihemaiti, Jin-Shuai Lan, Rodney J. Y. Ho
Publikováno v:
Chemical Communications. 56:1219-1222
To monitor delicate changes of biological HOCl in vivo, a new probe (OH-substituted coumarin-hemicyanine, probe 2) was synthesized for NIR and ratiometric HOCl detection. Selectivity studies indicated that the electron-donating group (OH) substituted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921cb21480be551a05c0531b80076212
https://doi.org/10.1039/c9cc06477j
https://doi.org/10.1039/c9cc06477j
Publikováno v:
RSC Med Chem
A series of chromone and donepezil hybrids were designed, synthesized, and evaluated as multipotent cholinesterase (ChE) and monoamine oxidase (MAO) inhibitors for the potential therapy of Alzheimer's disease (AD). In vitro studies showed that the gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762f5db308772156e8caf2eb825c3d5f
https://doi.org/10.1039/c9md00441f
https://doi.org/10.1039/c9md00441f
Autor:
Zheng-Hao Hu, Tong Zhang, Que Yuanfang, Yue Ding, Rui-Feng Zeng, Yi Chen, Jing Guo, Rodney J. Y. Ho, Hong-Xin Li, Jing-Yi Gu, Jin-Shuai Lan, Xiao-Yi Jiang
Publikováno v:
Analytica Chimica Acta. 1094:70-79
To explore how hypochlorous acid (HClO) affects human health, a highly sensitive, selective, and trace detection method for hypochlorite (ClO−) is crucial for determining its non-negligible function in both environment and living systems. Herein, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfba52cb3dc4889f3e7eed476bf97376
https://doi.org/10.1016/j.aca.2019.09.076
https://doi.org/10.1016/j.aca.2019.09.076
Autor:
Yun Liu, Rodney J. Y. Ho, Jin-Shuai Lan, Lu Zhen, Rui-Feng Zeng, Yue Ding, Yu Wang, Tong Zhang
Publikováno v:
Journal of hazardous materials. 424
SO2 and its derivatives (SO32-/HSO3-) are used widely in food, beverages, and pharmaceutical production. However, they could induce multiple diseases in respiratory, nervous, and cardiovascular systems. Although several fluorescent probes have been d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d864d75477ddd37cc68239635057cd
https://pubmed.ncbi.nlm.nih.gov/34653860
https://pubmed.ncbi.nlm.nih.gov/34653860
Publikováno v:
Sensors and Actuators B: Chemical. 268:328-337
A new ratiometric fluorescent probe IP based on pyrene-containing 1,2,3,3-tetramethyl-3H-indolium has been designed and synthesized for detecting SO2 in aqueous environment. The probe IP exhibited a dual colorimetric and ratiometric response toward S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65dabddf34fbef5460ad152289b9f325
https://doi.org/10.1016/j.snb.2018.04.047
https://doi.org/10.1016/j.snb.2018.04.047
Autor:
Xin-Yu Zhang, Yun Liu, Tong Zhang, Sai-Sai Xie, Jin-Shuai Lan, Yue Ding, Jian-Wei Hou, Ping Kang
Publikováno v:
European Journal of Medicinal Chemistry. 139:48-59
Combining N-benzyl pyridinium moiety and coumarin into in a single molecule, novel hybrids with ChE and MAO-B inhibitory activities were designed and synthesized. The biological screening results indicated that most of compounds displayed potent inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4301fec79fce6c559559f5dc8db7b31d
https://doi.org/10.1016/j.ejmech.2017.07.055
https://doi.org/10.1016/j.ejmech.2017.07.055