Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Jin-Qiu Zhou"'
Publikováno v:
eLife, Vol 12 (2024)
Telomeres, which are chromosomal end structures, play a crucial role in maintaining genome stability and integrity in eukaryotes. In the baker’s yeast Saccharomyces cerevisiae, the X- and Y’-elements are subtelomeric repetitive sequences found in
Externí odkaz:
https://doaj.org/article/f706a57492e2442286376452d2211c93
Autor:
Yuang Wang, Zhen Qu, Yi Fang, Yulong Chen, Jiayin Peng, Jiawen Song, Jinsong Li, Jiantao Shi, Jin-Qiu Zhou, Yun Zhao
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-14 (2023)
Abstract Chromosomes occupy discrete spaces in the interphase cell nucleus, called chromosome territory. The structural and functional relevance of chromosome territory remains elusive. We fused chromosome 15 and 17 in mouse haploid embryonic stem ce
Externí odkaz:
https://doaj.org/article/97f7c4db44ee4195ba405e9e3b70ab7a
Autor:
Jin-Qiu Zhou, Li Zeng, Qiao Zhang, Xin-Yao Wu, Meng-Lan Zhang, Xing-Tao Jing, Yu-Fang Wang, Hua-Tian Gan
Publikováno v:
The Saudi Journal of Gastroenterology, Vol 26, Iss 6, Pp 312-320 (2020)
Background: The role of Epstein–Barr virus (EBV) in inflammatory bowel disease (IBD) remains to be elucidated. The aim of this study was to investigate the presence of EBV in the blood and intestinal mucosa of patients with IBD and evaluate the ass
Externí odkaz:
https://doaj.org/article/3b5d2452c4c54697a8215c691f3983c2
Autor:
Zhi-Jing Wu, Jia-Cheng Liu, Xin Man, Xin Gu, Ting-Yi Li, Chen Cai, Ming-Hong He, Yangyang Shao, Ning Lu, Xiaoli Xue, Zhongjun Qin, Jin-Qiu Zhou
Publikováno v:
eLife, Vol 9 (2020)
Telomeres define the natural ends of eukaryotic chromosomes and are crucial for chromosomal stability. The budding yeast Cdc13, Stn1 and Ten1 proteins form a heterotrimeric complex, and the inactivation of any of its subunits leads to a uniformly let
Externí odkaz:
https://doaj.org/article/d1d0382480b540a39cf37dfecaca48d3
Autor:
Zhen Zhou, Yu-Ting Liu, Li Ma, Ting Gong, Ya-Nan Hu, Hong-Tao Li, Chen Cai, Ling-Li Zhang, Gang Wei, Jin-Qiu Zhou
Publikováno v:
eLife, Vol 6 (2017)
Histone tail modifications can greatly influence chromatin-associated processes. Asymmetrically modified nucleosomes exist in multiple cell types, but whether modifications on both sister histones contribute equally to chromatin dynamics remains elus
Externí odkaz:
https://doaj.org/article/dce300acb57d462da3d088f17350bac8
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005071 (2015)
DNA double strand break (DSB) is one of the major damages that cause genome instability and cellular aging. The homologous recombination (HR)-mediated repair of DSBs plays an essential role in assurance of genome stability and cell longevity. Telomer
Externí odkaz:
https://doaj.org/article/1c94cbe038954d4585f31fecf6a1fd94
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90644 (2014)
In telomerase negative yeast cells, Rad52-dependent recombination is activated to maintain telomeres. This recombination-mediated telomere elongation usually involves two independent pathways, type I and type II, and leads to generation of type I and
Externí odkaz:
https://doaj.org/article/886e284bfc4b43d4b61f2af1d1a9fdb2
Autor:
Yan Hu, Hong-Bo Tang, Ning-Ning Liu, Xia-Jing Tong, Wei Dang, Yi-Min Duan, Xiao-Hong Fu, Yang Zhang, Jing Peng, Fei-Long Meng, Jin-Qiu Zhou
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003208 (2013)
Telomeres are protein-DNA structures found at the ends of linear chromosomes and are crucial for genome integrity. Telomeric DNA length is primarily maintained by the enzyme telomerase. Cells lacking telomerase will undergo senescence when telomeres
Externí odkaz:
https://doaj.org/article/57ea2c6d8b024107b6c583965c048ad0
Autor:
Bo O Zhou, Shan-Shan Wang, Yang Zhang, Xiao-Hong Fu, Wei Dang, Brian A Lenzmeier, Jin-Qiu Zhou
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1001272 (2011)
Recent studies have established that the highly condensed and transcriptionally silent heterochromatic domains in budding yeast are virtually dynamic structures. The underlying mechanisms for heterochromatin dynamics, however, remain obscure. In this
Externí odkaz:
https://doaj.org/article/6b0668476e9b42c8848f024cca583740
Publikováno v:
PLoS Genetics, Vol 5, Iss 6, p e1000535 (2009)
Telomeres are nucleoprotein structures located at the linear ends of eukaryotic chromosomes. Telomere integrity is required for cell proliferation and survival. Although the vast majority of eukaryotic species use telomerase as a primary means for te
Externí odkaz:
https://doaj.org/article/a04b6d127db94be3bcba0b18b34d5785