Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jin-Ping Lai"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 4, Pp 781-797 (2020)
Significant progress has been made in our understanding of the role of epigenetic modifiers in many types of human cancer. Here, we review currently available studies on the unique histone methyltransferase, SETD2, which is responsible for H3 lysine
Externí odkaz:
https://doaj.org/article/65ce75036cbf4381a864ca35ffe5e813
Publikováno v:
Annals of Hepatology, Vol 16, Iss 2, Pp 304-307 (2017)
Externí odkaz:
https://doaj.org/article/fd8faeb23b204870a0d7f294374902a1
Autor:
Marshall W. Meeks, Umar M. Kamal, Muhammad B. Hammami, Jason R. Taylor, M. Louay Omran, Yongxin Chen, Jin-Ping Lai
Publikováno v:
Case Reports in Gastrointestinal Medicine, Vol 2016 (2016)
Pyogenic granuloma (PG), more accurately known as lobular capillary hemangioma, is a benign vascular tumor that usually occurs in the skin or oral mucosa. This lesion is rarely reported in the gastrointestinal tract but is known to bleed if not resec
Externí odkaz:
https://doaj.org/article/e028f566c9e24c53a9593ad6c8fc1aad
Publikováno v:
Case Reports in Otolaryngology, Vol 2016 (2016)
Background. Submandibular oncocytomas are rare benign salivary gland neoplasms. They are typically found in Caucasian patients aged 50–70 years with no gender preference. Due to the overlapping histological and clinical features of head and neck tu
Externí odkaz:
https://doaj.org/article/f97be55f3a8e40f39682a251f5d7e41b
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 4: Evaluation of pharmacodynamics endpoints confirms on target activity of SERDs and palbociclib, resulting in sustained inhibition of tumors receiving both treatments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee29c5e6c07b5a865bf126f1bef796e
https://doi.org/10.1158/1078-0432.22454688
https://doi.org/10.1158/1078-0432.22454688
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 1: SERDs and SERMs differ in their ability to inhibit ER-dependent stimulation of breast cancer cell proliferation by growth factors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45421649f6c61cc430618d3b84ec6afd
https://doi.org/10.1158/1078-0432.22454700
https://doi.org/10.1158/1078-0432.22454700
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 3: SERDs and palbociclib inhibit breast cancer cell proliferation by independent mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913466b83847b02760d8832503645b8d
https://doi.org/10.1158/1078-0432.22454691.v1
https://doi.org/10.1158/1078-0432.22454691.v1
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 2: SERDs inhibit the constitutive activity of the clinically relevant Y537N,D538G ESR1 double mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e5398bfcdac49fc14ce14291926781
https://doi.org/10.1158/1078-0432.22454697.v1
https://doi.org/10.1158/1078-0432.22454697.v1
Autor:
Shunqiang Li, Donald P. McDonnell, John D. Norris, Jin-Ping Lai, Robert Crowder, Jieya Shao, Elizabeth Griffin, Tina Primeau, Kim T. Arndt, Stephen G. Dann, Todd VanArsdale, Koleen Eisele, Holly M. Alley, Matthew J. Ellis, Suzanne E. Wardell
Supplemental figure 5: IHC analysis of treated PDX tumors indicated on-target activity of bazedoxifene and palbociclib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::741a8d0744eed5814f3385c071daffe5
https://doi.org/10.1158/1078-0432.22454685
https://doi.org/10.1158/1078-0432.22454685
Autor:
Xia Qian, Wei Zhang, Alireza Shams, Jin-Ping Lai, Alex S. Befeler, Kahee A. Mohammed, Ningling Kang
Publikováno v:
Liver research
Liver Research, Vol 4, Iss 4, Pp 212-217 (2020)
Liver Research, Vol 4, Iss 4, Pp 212-217 (2020)
Background and aim The transcriptional co-activator Yes-associated protein-1 (YAP1) has been implicated as an oncogene and is overexpressed in different kinds of human cancers, especially hepatocellular carcinoma (HCC). However, the role of YAP1 has