Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jin-Mu Yi"'
Autor:
Musun Park, Sang-Min Park, Haeseung Lee, Aeyung Kim, No Soo Kim, Yu Ri Kim, Jin-Mu Yi, Seongwon Cha
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract Traditional herbal medicine, rooted in a long history of use in East Asia, combines several herbs to create treatments showing high efficacy with minimal side effects, for specific diseases. Such combination therapies represent a potential r
Externí odkaz:
https://doaj.org/article/a864145251ab4a32bb6139c24bb8e923
Publikováno v:
Life, Vol 14, Iss 10, p 1246 (2024)
Bojungikki-Tang (BJIKT) is traditionally used to enhance digestive function and immunity. It has gained attention as a supplement to chemotherapy or targeted therapy owing to its immune-boosting properties. This study aimed to evaluate the synergisti
Externí odkaz:
https://doaj.org/article/c0c18ff276be4d01805f13a3fc343cff
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 18, p 10219 (2024)
Herbs, such as Aconitum carmichaeli Debeaux (ACD), have long been used as therapies, but it is difficult to identify which organs of the human body are affected by the various compounds. In this study, we predicted the organ where the drug predominan
Externí odkaz:
https://doaj.org/article/9dd82a067d4e418e9897668a009996c7
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4636 (2024)
We characterized the therapeutic biological modes of action of several terpenes in Poria cocos F.A Wolf (PC) and proposed a broad therapeutic mode of action for PC. Molecular docking and drug-induced transcriptome analysis were performed to confirm t
Externí odkaz:
https://doaj.org/article/c8365224f29c491f9c938baf1f4107de
Autor:
Sung-Yoon Yang, Jin-Mu Yi, Jaemoo Chun, Seongwon Park, Tham Thi Bui, Hwi-Yeol Yun, Jung-Woo Chae, Mi-Kyung Jeong
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Atezolizumab (a PD-L1 inhibitor) has shown remarkable efficacy and tolerability in various cancer types. Despite its efficacy and safety, atezolizumab monotherapy has limitations, such as acquired resistance and adverse events. Bojungikki-tang (BJIKT
Externí odkaz:
https://doaj.org/article/0bf0127b0ada43e0b01a99b360221691
Autor:
Sang-Min Park, Aeyung Kim, Haeseung Lee, Su-Jin Baek, No Soo Kim, Musun Park, Jin-Mu Yi, Seongwon Cha
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pharmacogenomic analysis based on drug transcriptomic signatures is widely used to identify mechanisms of action and pharmacological indications. Despite accumulating reports on the efficacy of medicinal herbs, related transcriptome-level analyses ar
Externí odkaz:
https://doaj.org/article/7a4c46a1529e4ac2b11518de4abb01eb
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Immune checkpoint blockage targeting PD-L1 has led to breakthroughs in cancer treatment. Although anti-PD-L1-based immunotherapy has been approved as standard therapy in various cancer types, its therapeutic efficacy in most colorectal cancers (CRC)
Externí odkaz:
https://doaj.org/article/de305839b1af45c188373a86181f8882
Autor:
Su-Jin Baek, Haeseung Lee, Sang-Min Park, Musun Park, Jin-Mu Yi, No Soo Kim, Aeyung Kim, Seongwon Cha
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 148, Iss , Pp 112748- (2022)
Paeoniae Radix (PR) has a great therapeutic value in many clinical applications; however, the presence of various bioactive compounds and its complicated effects on human health makes its precise mechanisms of action unclear. This study investigated
Externí odkaz:
https://doaj.org/article/a2c452fba5a44b7ca5df0449d1311e6b
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 19, Iss 1, Pp 1-13 (2019)
Abstract Background The dried fruits of Forsythia suspensa has generally been used to clear heat and detoxify in traditional Korean and Chinese medicine. Oxaliplatin is a first-line treatment chemotherapeutic agent for advanced colorectal cancer, but
Externí odkaz:
https://doaj.org/article/34bbbb18bb694114bf00e4d4ff62e579
Publikováno v:
Molecules, Vol 24, Iss 6, p 1177 (2019)
The dried fruits of Forsythia viridissima have been prescribed to relive fever, pain, vomiting, and nausea in traditional medicine. Oxaliplatin (LOHP) is used to treat advanced colorectal cancer; however, it frequently induces peripheral neuropathies
Externí odkaz:
https://doaj.org/article/9b56ebc9690d4cc8a5e38c9971ecd55b