Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Jin-Long Qiu"'
Autor:
Teng-Fei Tian, Fu-Hao Mo, Hao-Yang Su, Can Huang, Hui Zhao, Jun Liu, Bo Shang, Kui Li, Jin-Long Qiu
Publikováno v:
Chinese Journal of Traumatology, Vol 27, Iss 4, Pp 235-241 (2024)
Purpose: Under-foot impact loadings can cause serious lower limb injuries in many activities, such as automobile collisions and underbody explosions to military vehicles. The present study aims to compare the biomechanical responses of the mainstream
Externí odkaz:
https://doaj.org/article/c733225c8031483396d7df71b0a4fd19
Autor:
Chao Li, Yuan Zong, Shuai Jin, Haocheng Zhu, Dexing Lin, Shengnan Li, Jin-Long Qiu, Yanpeng Wang, Caixia Gao
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract We describe here a CRISPR simultaneous and wide-editing induced by a single system (SWISS), in which RNA aptamers engineered in crRNA scaffold recruit their cognate binding proteins fused with cytidine deaminase and adenosine deaminase to Ca
Externí odkaz:
https://doaj.org/article/da664272e5b441639ec4000dd23f2a75
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract The CRISPR/Cas9 system is unable to edit all targetable genomic sites with full efficiency in vivo. We show that Cas9-mediated editing is more efficient in open chromatin regions than in closed chromatin regions in rice. A construct (Cas9-TV
Externí odkaz:
https://doaj.org/article/531fec53d0964ca4864778b162b7f00b
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-7 (2017)
Abstract High-fidelity SpCas9 variants (eSpCas9 and SpCas9-HF1) have been engineered to reduce off-target effects. We found that changes in guide RNA length induced significant reductions in the editing activities of SpCas9 variants in plant cells. S
Externí odkaz:
https://doaj.org/article/36640f1a85934dc4b03db185e13b9a8c
Autor:
Jiaying Huang, Qiupeng Lin, Hongyuan Fei, Zixin He, Hu Xu, Yunjia Li, Kunli Qu, Peng Han, Qiang Gao, Boshu Li, Guanwen Liu, Lixiao Zhang, Jiacheng Hu, Rui Zhang, Erwei Zuo, Yonglun Luo, Yidong Ran, Jin-Long Qiu, Kevin Tianmeng Zhao, Caixia Gao
SummaryThe elucidation of protein function and its exploitation in bioengineering have greatly contributed to the development of the life sciences. Existing protein mining efforts generally rely on amino acid sequences rather than protein structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cce29881701a8d77ee83a21dd1c07033
https://doi.org/10.1101/2023.05.21.541555
https://doi.org/10.1101/2023.05.21.541555
Autor:
Yi Zhang, Zhen Liang, Yuan Zong, Yanpeng Wang, Jinxing Liu, Kunling Chen, Jin-Long Qiu, Caixia Gao
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Plant genome editing typically relies upon transgenic intermediates, which is a concern given the current regulatory requirements concerning GMOs. Here, Zhang et al. describe a method to edit wheat genomes by transiently expressing CRISPR/Cas9 DNA or
Externí odkaz:
https://doaj.org/article/5eeff47d0d90427daddfe48074ff7432
Autor:
Shengnan Li, Dexing Lin, Yunwei Zhang, Min Deng, Yongxing Chen, Bin Lv, Boshu Li, Yuan Lei, Yanpeng Wang, Long Zhao, Yueting Liang, Jinxing Liu, Kunling Chen, Zhiyong Liu, Jun Xiao, Jin-Long Qiu, Caixia Gao
Publikováno v:
Nature. 602:455-460
Disruption of susceptibility (S) genes in crops is an attractive breeding strategy for conferring disease resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab70bf070e76f3c16ff2788e90b2cfb8
https://doi.org/10.1038/s41586-022-04395-9
https://doi.org/10.1038/s41586-022-04395-9
Autor:
Zixu Zhu, Dandan Zhang, Jin-Long Qiu, Yanpeng Wang, Shengnan Li, Chao Sun, Dexing Lin, Guanwen Liu, Caixia Gao, Chenxiao Xue, Qiupeng Lin
Publikováno v:
Journal of Genetics and Genomics. 48:444-451
MAD7 is an engineered nuclease of the Class 2 type V-A CRISPR-Cas (Cas12a/Cpf1) family with a low level of homology to canonical Cas12a nucleases. It has been publicly released as a royalty-free nuclease for both academic and commercial use. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84a0ae8983e66f7fdf0482489eb5407
https://doi.org/10.1016/j.jgg.2021.04.003
https://doi.org/10.1016/j.jgg.2021.04.003
Autor:
Yuan Zong, Jiayang Li, Qiupeng Lin, Hong Yu, Yanpeng Wang, Guanwen Liu, Liquan Kou, Zixu Zhu, Caixia Gao, Jin-Long Qiu, Shuai Jin
Publikováno v:
Nature Biotechnology. 39:923-927
Prime editing (PE) applications are limited by low editing efficiency. Here we show that designing prime binding sites with a melting temperature of 30 °C leads to optimal performance in rice and that using two prime editing guide (peg) RNAs in tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2e1c47ecf10e157b71d464bbd7fa66b
https://doi.org/10.1038/s41587-021-00868-w
https://doi.org/10.1038/s41587-021-00868-w
Autor:
Dandan Jiang, Dandan Zhang, Shengnan Li, Yueting Liang, Qianwei Zhang, Xu Qin, Jinlan Gao, Jin‐Long Qiu
Publikováno v:
Molecular plant pathology. 23(4)
Efficient and modular genome editing technologies that manipulate the genome of bacterial pathogens will facilitate the study of pathogenesis mechanisms. However, such methods are yet to be established for Xanthomonas oryzae pv. oryzae (Xoo), the cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21daaa5c896655d95c96ff7903ee9df
https://pubmed.ncbi.nlm.nih.gov/34954876
https://pubmed.ncbi.nlm.nih.gov/34954876