Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jin-Liang Sui"'
Autor:
Morten Grunnet, Jin Liang Sui, Morten Duno, Lasse Steen Ravn, Kirstine Calloe, Nicole Schmitt, Søren-Peter Olesen, Stig Haunsø, Jesper Hastrup Svendsen
Publikováno v:
Biochemical and Biophysical Research Communications. 364:889-895
Kir3.4 and Kir3.1 potassium channel subunits mediate the acetylcholine induced inwardly rectifying current I(KACh) in the heart. We found a glycine to arginine substitution in codon 247 of Kir3.4 in a patient with a single episode of atrial fibrillat
Autor:
Emiliano Medei, Diomedes E. Logothetis, Coeli M. Lopes, Juan Remon, Inna Keselman, Jin Liang Sui, Yuming Shen, Alessandra Matavel, Tibor Rohacs, Avia Rosenhouse-Dantsker
Publikováno v:
Channels. 1:124-134
Neurotransmitter and hormone regulation of cellular function can result from a concomitant stimulation of different signaling pathways. Signaling cascades are strongly regulated during disease and are often targeted by commonly used drugs. Crosstalk
Autor:
Julieta Palomeque, Alison D. Schecter, George A. Diaz, Jin-Liang Sui, James R. Tunstead, Diomedes E. Logothetis, Burns C. Blaxall, Robert Pyo, Ashwini Dhume, Roger J. Hajjar
Publikováno v:
Journal of Molecular and Cellular Cardiology. 41:834-844
The inflammatory response is critical to the development and progression of heart failure. Chemokines and their receptors are a distinct class of inflammatory modulators that may play a role in mediating myocardial dysfunction in heart failure. Level
Publikováno v:
Proceedings of the National Academy of Sciences. 95:1307-1312
The βγ subunits of GTP-binding proteins (G βγ ) activate the muscarinic K + channel (K ACh ) in heart by direct binding to both of its component subunits. K ACh channels can also be gated by internal Na + ions. Both activation mechanisms show dep
Autor:
M. N. Langan, A. Pabon, J. A. Kozak, K. W. Chan, Jin Liang Sui, D. E. Logothetis, J. A. A. Ladias
Publikováno v:
The Journal of General Physiology
GTP-binding (G) proteins have been shown to mediate activation of inwardly rectifying potassium (K+) channels in cardiac, neuronal and neuroendocrine cells. Here, we report functional expression of a recombinant inwardly rectifying channel which we c
Publikováno v:
The Journal of General Physiology
Muscarinic potassium channels (KACh) are composed of two subunits, GIRK1 and GIRK4 (or CIR), and are directly gated by G proteins. We have identified a novel gating mechanism of KACh, independent of G-protein activation. This mechanism involved funct
Autor:
Avia Rosenhouse-Dantsker, Jin Liang Sui, Lily Yeh Jan, Kim W. Chan, Taihao Jin, Diomedes E. Logothetis
Publikováno v:
Channels (Austin, Tex.). 2(1)
Phosphatidylinositol bisphosphate (PIP(2)) is the most abundant phosphoinositide in the plasma membrane of cells and its interaction with many ion channel proteins has proven to be a critical factor enabling ion channel gating. All members of the inw
Autor:
Xiaying Wu, William B. Thornhill, Amanda Pabon, Kim W. Chan, Diomedes E. Logothetis, Jin Liang Sui
Publikováno v:
The Journal of biological chemistry. 275(39)
GIRK (G protein-gated inward rectifier K(+) channel) proteins play critical functional roles in heart and brain physiology. Using antibodies directed to either GIRK1 or GIRK4, site-directed mutagenesis, and specific glycosidases, we have investigated
Chapter 18 Effect of Phosphatidylinositol Phosphates on the Gating of G-Protein-Activated K+Channels
Publisher Summary This chapter discusses the molecular mechanism by which adenosine triphosphate (ATP) hydrolysis affects K channel gating by the G βγ subunits or intracellular Na + ions. The data support the hypothesis that hydrolysis of ATP gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3babac2179c70bf2f25dc508fdeb23a2
https://doi.org/10.1016/s0070-2161(08)60934-x
https://doi.org/10.1016/s0070-2161(08)60934-x