Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Jin-Lei Wang"'
Autor:
Zhi-Wei Zhang, Meng Wang, Li-Xiu Sun, Hany M. Elsheikha, Cheng-Lin Lei, Jin-Lei Wang, Bao-Quan Fu, Jian-Xun Luo, Xing-Quan Zhu, Ting-Ting Li
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Background To successfully replicate within the host cell, Toxoplasma gondii employs several mechanisms to overcome the host cell defenses and mitigate the harmful effects of the free radicals resulting from its own metabolic processes using
Externí odkaz:
https://doaj.org/article/d5526581245047be8aa269604713f5e4
Autor:
Jin-Lei Wang, Ting-Ting Li, Nian-Zhang Zhang, Meng Wang, Li-Xiu Sun, Zhi-Wei Zhang, Bao-Quan Fu, Hany M. Elsheikha, Xing-Quan Zhu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Sexual development in Toxoplasma gondii is a multistep process that culminates in the production of oocysts, constituting approximately 50% of human infections. However, the molecular mechanisms governing sexual commitment in this parasite r
Externí odkaz:
https://doaj.org/article/e638c14ad26d41a2aa0003e92c32ea80
Autor:
Qin-Li Liang, Lan-Bi Nie, Hany M Elsheikha, Ting-Ting Li, Li-Xiu Sun, Zhi-Wei Zhang, Meng Wang, Bao-Quan Fu, Xing-Quan Zhu, Jin-Lei Wang
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011831 (2023)
Protein phosphatases are post-translational regulators of Toxoplasma gondii proliferation, tachyzoite-bradyzoite differentiation and pathogenesis. Here, we identify the putative protein phosphatase 6 (TgPP6) subunits of T. gondii and elucidate their
Externí odkaz:
https://doaj.org/article/8590a3ac1a01496686967608ba868479
Autor:
Jin-Lei Wang, Ting-Ting Li, Hany M. Elsheikha, Qin-Li Liang, Zhi-Wei Zhang, Meng Wang, L. David Sibley, Xing-Quan Zhu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Protein phosphorylation and dephosphorylation are essential aspects of biology. Wang et al., report that Toxoplasma gondiiprotein phosphatase 2A (PP2A) mediated dephosphorylation is critical for starch metabolism and bradyzoite differentiation.
Externí odkaz:
https://doaj.org/article/7f82e55342d84b79904c1f1e0b2aaa28
Autor:
Xiao-Nan Zheng, Jin-Lei Wang, Hany M. Elsheikha, Meng Wang, Zhi-Wei Zhang, Li-Xiu Sun, Xin-Cheng Wang, Xing-Quan Zhu, Ting-Ting Li
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The analysis of the subcellular localization and function of dense granule proteins (GRAs) is of central importance for the understanding of host-parasite interaction and pathogenesis of Toxoplasma gondii infection. Here, we identified 15 no
Externí odkaz:
https://doaj.org/article/41ea767327e241b1bfe06db046ae4343
Autor:
Qin-Li Liang, Lan-Bi Nie, Ting-Ting Li, Hany M. Elsheikha, Li-Xiu Sun, Zhi-Wei Zhang, Dan-Yu Zhao, Xing-Quan Zhu, Jin-Lei Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Protein serine/threonine phosphatases (PSPs), found in various plants and protozoa, are involved in the regulation of various biological processes. However, very little is known about the role of PSPs in the pathogenicity of the apicomplexan protozoa
Externí odkaz:
https://doaj.org/article/8091b657956142b888e3d33f87992730
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-4 (2019)
Abstract Background Little information about the prevalence of gastrointestinal parasites in yaks (Bos grunniens) in northwest China is available. Therefore, the objective of the study was to quantify faecal egg counts of gastrointestinal parasites (
Externí odkaz:
https://doaj.org/article/d728d86641894802bd019ec1aa762dec
Autor:
Zhi-Wei Zhang, Ting-Ting Li, Jin-Lei Wang, Qin-Li Liang, Hai-Sheng Zhang, Li-Xiu Sun, Xing-Quan Zhu
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2021)
Toxoplasmosis caused by infection with Toxoplasma gondii is an important parasitic zoonosis with a worldwide distribution. In this study, we examined the functions of two thioredoxins (namely CTrp26 and CTrx1) of T. gondii tachyzoites by generation o
Externí odkaz:
https://doaj.org/article/0537657b74fd4dd8a3136f99113da23d
Autor:
Zhong-Yuan Li, Hai-Ting Guo, Guillermo Calderón-Mantilla, Jun-Jun He, Jin-Lei Wang, Boyan B. Bonev, Xing-Quan Zhu, Hany M. Elsheikha
Publikováno v:
International Journal of Medical Microbiology, Vol 310, Iss 5, Pp 151432- (2020)
The extracellular signal-regulated kinases (ERKs) serve as important determinants of cellular signal transduction pathways, and hence may play important roles during infections. Previous work suggested that putative ERK7 of Toxoplasma gondii is requi
Externí odkaz:
https://doaj.org/article/366edf3243e94b52add08037025e73b8
Publikováno v:
Iranian Journal of Parasitology, Vol 14, Iss 4 (2019)
Background: Toxoplasma gondii can infect all the warm-blooded vertebrates and cause serious toxoplasmosis. Extracellular signal-regulated kinase 7 in T. gondii (TgERK7) mediated the proliferation of this parasite may be a potential vaccine candidate.
Externí odkaz:
https://doaj.org/article/94e18d09358346e8b3bd3a92f21e1ca8