Bu-Yin-Qian-Zheng Formula Ameliorates MPP+-Induced Mitochondrial Dysfunction in Parkinson’s Disease via Parkin

Autor: Hao-Jie Ma, Cong Gai, Yuan Chai, Wan-Di Feng, Cui-Cui Cheng, Jin-Kun Zhang, Yu-Xin Zhang, Lu-Ping Yang, Zhen-Yu Guo, Yu-Shan Gao, Hong-Mei Sun

Publikováno v: Frontiers in Pharmacology, Vol 11 (2020)

As a typical traditional Chinese medicine, Bu-Yin-Qian-Zheng Formula (BYQZF) has been shown to have neuroprotective effects in patients with Parkinson’s disease (PD), particularly by ameliorating mitochondrial dysfunction and regulating expression

Externí odkaz: https://doaj.org/article/f7a4b2fed43a41e38a0c7a4bdcea5ae9

Protective effects of Buyinqianzheng Formula on mitochondrial morphology by PINK1/Parkin pathway in SH-SY5Y cells induced by MPP+

Autor: Jin-Kun Zhang, Yuxin Zhang, Wan-Di Feng, Hao-Jie Ma, Lu-Ping Yang, Hong-Mei Sun, Cong Gai, Yushan Gao, Zhen-Yu Guo, Cui-Cui Cheng

Publikováno v: Journal of Traditional Chinese Medical Sciences, Vol 7, Iss 3, Pp 274-282 (2020)

Objective Buyinqianzheng Formula (BYQZF) is clinically employed in traditional Chinese medicine to treat Parkinson’s disease (PD) by improving mitochondrial dysfunction. However, the underlying mechanisms by which BYQZF affects mitochondrial morpho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd95d839d12382f80bfcd0014b7cd8ce
http://www.sciencedirect.com/science/article/pii/S2095754820300697

Expression of PNNs and the functional changes of GABA-ergic neurons in the medial prefrontal cortex in a rat model of depression.

Autor: Yu-Xin Zhang, Cong Gai, Hao-Jie Ma, Cui-Cui Cheng, Jin-Kun Zhang, Lu-Ping Yang, Wan-Di Feng, Meng-Qi Zhou, Hai-Hong Zhao, Die Hu, Hong-Mei Sun

Publikováno v: Journal of Hainan Medical University; Feb2021, Vol. 27 Issue 4, p1-5, 5p

Dual Agent Loaded PLGA Nanoparticles Enhanced Antitumor Activity in a Multidrug-Resistant Breast Tumor Xenograft Model

Autor: Jin-Kun Zhang, Bei Xu, Yang Yang, Huili Li, Xue-Lian Zheng, Xiangrong Song, Dailong Fang, Yan Chen, Ke Ren, Yi Lei

Publikováno v: International Journal of Molecular Sciences, Vol 15, Iss 2, Pp 2761-2772 (2014)
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 15; Issue 2; Pages: 2761-2772

Multidrug-resistant breast cancers have limited and ineffective clinical treatment options. This study aimed to develop PLGA nanoparticles containing a synergistic combination of vincristine and verapamil to achieve less toxicity and enhanced efficac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979e630d972db33511a11cb0ed411fac
https://doi.org/10.3390/ijms15022761

Dual-Functional PEI-Poly(γ-Cholesterol-l -Glutamate) Copolymer for Drug/Gene Co-delivery

Autor: Dailong Fang, Ke Ren, Qing Ma, Jin-Kun Zhang, Zhiyao He, Bo Li, Xiangrong Song, Lili He, Gu He, Shi Zeng, Rui Zhou

Publikováno v: Macromolecular Chemistry and Physics. 215:163-170

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ff3d7c7c146c55dadcc1ee9890710fa
https://doi.org/10.1002/macp.201300551