Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Jin-Ku Bao"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Parkinson’s disease (PD) is one of the neurodegenerative diseases that is characterized by obvious motor and some nonmotor symptoms. Various therapeutics failed in the effective treatment of PD because of impaired neurological function in the brain
Externí odkaz:
https://doaj.org/article/a74a6bc4de21403892f7aa7fb03c7c5c
Publikováno v:
Thoracic Cancer, Vol 10, Iss 4, Pp 715-727 (2019)
Background Although cigarette smoking is considered one of the key risk factors for lung cancer, 15% of male patients and 53% of female patients with lung cancer are non‐smokers. Metabolic changes are critical features of cancer. Therapeutic target
Externí odkaz:
https://doaj.org/article/0405fdf543dc4ebbaa51c230a03c18fe
Publikováno v:
Journal of the Formosan Medical Association, Vol 113, Iss 3, Pp 143-147 (2014)
The newly emerged Middle East respiratory syndrome coronavirus (MERS-CoV) is becoming another “SARS-like” threat to the world. It has an extremely high death rate (∼50%) as there is no vaccine or efficient therapeutics. The identification of th
Externí odkaz:
https://doaj.org/article/327b84e85ed84d4baa42639fddf7ed16
Autor:
Kang-Kang Yu, Kun Li, Hao-Yuan Wang, Xiao-Liang Li, Si-Xian Wu, Wen-Ming Xu, Yan-Hong Liu, Chuan-Fang Wu, Xiao-Qi Yu, Jin-Ku Bao
Publikováno v:
Analytical Chemistry; 7/23/2024, Vol. 96 Issue 29, p11915-11922, 8p
Autor:
Yongmei Xie, Kang-Kang Yu, Chun-Yan Lu, Qian Zhou, Kun Li, Xiao-Qi Yu, Jin-Ku Bao, Yan-Hong Liu
Publikováno v:
Nanoscale. 12:2002-2010
A number of multimodal agents have been developed for tumour imaging and diagnosis, but most of them cannot be used to study the detailed physiological or pathological changes in living cells at the same time. Herein, a series of pH-responsive magnet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7db4c3062c315a14f842694b97b350
https://doi.org/10.1039/c9nr06347a
https://doi.org/10.1039/c9nr06347a
Autor:
Shu Zhou, Wenzhao Liu, Rongsheng Tong, Yuxuan Zhu, Lei Zhong, Lan Bai, Qian Peng, Lingyu Su, Xingmei Duan, Jin-ku Bao, Jianyou Shi
Publikováno v:
Investigational New Drugs. 37:616-624
Esophageal squamous cell carcinoma (ESCC) is one of the most serious life-threatening malignancies. Although chemotherapeutic targets and agents for ESCC have made much progress recently, the efficacy is still unsatisfactory. Therefore, there is stil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00560129a64ce17dbdf74e33a4c0d503
https://doi.org/10.1007/s10637-018-0651-4
https://doi.org/10.1007/s10637-018-0651-4
Autor:
Xin Long, Lei Zhong, Qi Fu, Jin-ku Bao, Shu Zhou, Kai Chen, Xiao-Juan Jiang, Guo-Bo Li, Hui Li, Lin Luo
Publikováno v:
Organic & Biomolecular Chemistry. 16:1489-1495
Maternal embryonic leucine zipper kinase (MELK), a serine/threonine protein kinase, has oncogenic properties and plays a key functional role in various cancer cells. Although MELK may not be a cancer addiction target, the development of specific MELK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adae0f6f200f71597794bc2de2bcb97e
https://doi.org/10.1039/c7ob02344h
https://doi.org/10.1039/c7ob02344h
Publikováno v:
Sensors and Actuators B: Chemical. 321:128479
Inspired by the mechanism of aggregation induced emission, two derivatives of thiazole orange (TPE-mTO and Ph-TO) were rationally designed and prepared in this work. Their selectivity and sensitivity towards G-quadruplex were studied by fluorescence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d257fd576c6c4fae98b6169c47a51ee6
https://doi.org/10.1016/j.snb.2020.128479
https://doi.org/10.1016/j.snb.2020.128479
Publikováno v:
Zeitschrift für Naturforschung C. 70:7-13
Lectins, a group of highly diverse proteins of non-immune origin and are ubiquitously distributed in plants, animals and fungi, have multiple significant biological functions, such as anti-fungal, anti-viral and, most notably, anti-tumor activities.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449abdf8513846f38e90c4ed2b5b5f84
https://doi.org/10.1515/znc-2014-4108
https://doi.org/10.1515/znc-2014-4108
Publikováno v:
Helvetica Chimica Acta. 97:151-159
Seven new orsellinic acid esters, 1-7, and four known compounds were isolated from the solid, fermented rice culture of Chaetomium globosporum (cib-132). Their structures were elucidated by 1D- and 2D-NMR spectra, and the relative configuration of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1498ae9268540172b93905d7bc13d40
https://doi.org/10.1002/hlca.201300329
https://doi.org/10.1002/hlca.201300329