Zobrazeno 1 - 3
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pro vyhledávání: '"Jin-Kai Juang"'
Publikováno v:
Nucleic Acids Research. 20:467-473
The cutting sites specificity of topoisomerase II from porcine spleen were determined by a modified Sanger's DNA sequencing method. The topoisomerase II prefers to cut DNA at the 3' side of A and leave 5' protruding end with two staggering bases. Thr
Autor:
Hon-Ju Liu, Jin-Kai Juang
Publikováno v:
Biochemical and biophysical research communications. 146(3)
In the presence of 5% dimethylsulfoxide, 2.5 fold increase in vitro RNA synthesis rate by E. coli RNA polymerase was observed as superhelical pBR322 DNA was used as template. The effect of DMSO on DNA conformation was studied by: [i] measuring the di
Publikováno v:
Biochemical and biophysical research communications. 159(3)
Withangulatin A, a new compound with a known chemical structure and from the antitumor Chinese herb Physalis angulata L, was found to act on topoisomerase II to induce topoisomerase II-mediated DNA damage in vitro. It has two effective dosage ranges