Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Jin-Ju Byeon"'
Autor:
Jangmi Choi, Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, Byeong ill Lee, Yuri Park, Young G. Shin
Publikováno v:
Molecules, Vol 26, Iss 4, p 1179 (2021)
Sulfasalazine (SAS), an anti-inflammatory drug with potent cysteine/glutamate antiporter system xc-(SXC) inhibition has recently shown beneficial effects in brain-related diseases. Despite many reports related to central nervous system (CNS) effect o
Externí odkaz:
https://doaj.org/article/088dd43cd10944599185e7adb41d7059
Autor:
Seok-Ho Shin, Yuri Park, Min-Ho Park, Jin-Ju Byeon, Byeong ill Lee, Jangmi Choi, Young G. Shin
Publikováno v:
Life, Vol 10, Iss 7, p 115 (2020)
Neuro–inflammation is known to be one of the pathogenesis for the degenerative central nervous system (CNS) disease. Recently various approaches for the treatment of brain diseases by controlling neuro-inflammation in the brain have been introduced
Externí odkaz:
https://doaj.org/article/48f37666c46544e2bb516d7c43666f01
Autor:
Yuri Park, Min-Ho Park, Jin-Ju Byeon, Seok-Ho Shin, Byeong ill Lee, Jang-mi Choi, Nahye Kim, Seo-jin Park, Min-jae Park, Jeong-hyeon Lim, Young G. Shin
Publikováno v:
Molecules, Vol 25, Iss 9, p 2209 (2020)
5-Amino-7-(2-phenylethyl)-2-(2-furyl)-pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c) pyrimidine (SCH 58261) is one of the new chemical entities that has been developed as an adenosine A2A receptor antagonist. Although SCH 58261 has been reported to be benefic
Externí odkaz:
https://doaj.org/article/a2fbfb7bd6f649149d82cd8f281da431
Autor:
Byeong ill Lee, Min-Ho Park, Jin-Ju Byeon, Seok-Ho Shin, Jangmi Choi, Yuri Park, Yun-Hee Park, Jeiwook Chae, Young G. Shin
Publikováno v:
Molecules, Vol 25, Iss 7, p 1515 (2020)
The novel prenyl transferase-mediated, site-specific, antibody−drug conjugate LCB14-0110 is comprised of a proprietary beta-glucuronide linker and a payload (Monomethyl auristatin F, MMAF, an inhibitor for tubulin polymerization) attached to human
Externí odkaz:
https://doaj.org/article/670d518cadb940d9a7df2aeaa3297888
Autor:
Jin-Ju Byeon, Min-Ho Park, Seok-Ho Shin, Yuri Park, Byeong ill Lee, Jang-mi Choi, Nahye Kim, Seo-jin Park, Min-jae Park, Jeong-hyeon Lim, Young-Guk Na, Young G. Shin
Publikováno v:
Molecules, Vol 25, Iss 5, p 1106 (2020)
Parkinson’s disease is one of the most common neurodegenerative diseases. Adenosine regulates the response to other neurotransmitters in the brain regions related to motor function. In the several subtypes of adenosine receptors, especially, adenos
Externí odkaz:
https://doaj.org/article/a4b7679f09f4470ebb9c6dbc11c0aaa5
Autor:
Min-Ho Park, Byeong ill Lee, Jin-Ju Byeon, Seok-Ho Shin, Jangmi Choi, Yuri Park, Young G. Shin
Publikováno v:
Molecules, Vol 24, Iss 15, p 2754 (2019)
A simple liquid chromatography−quadrupole-time-of-flight−mass spectrometric assay (LC-TOF-MS/MS) has been developed for the evaluation of metabolism and pharmacokinetic (PK) characteristics of monomethyl auristatin F (MMAF) in rat, which is being
Externí odkaz:
https://doaj.org/article/1937c08029fd4848b762197dda7acf70
Autor:
Young-Guk Na, Jin-Ju Byeon, Hyun Wook Huh, Min-Ki Kim, Young G. Shin, Hong-Ki Lee, Cheong-Weon Cho
Publikováno v:
Pharmaceutics, Vol 11, Iss 7, p 354 (2019)
Tadalafil is a cytochrome P450 (CYP) 3A4 substrate. Because there are few data on drug-drug interactions, it is advisable to take sufficient consideration when co-administering tadalafil with CYP3A4 inducers or inhibitors. This study was conducted to
Externí odkaz:
https://doaj.org/article/17a7c4738cce4a36abcd2c418b1ab144
Autor:
Gi-Ho Son, Young-Guk Na, Hyun Wook Huh, Miao Wang, Min-Ki Kim, Min-Gu Han, Jin-Ju Byeon, Hong-Ki Lee, Cheong-Weon Cho
Publikováno v:
Pharmaceutics, Vol 11, Iss 5, p 222 (2019)
Ticagrelor (TGL), a P2Y12 receptor antagonist, is classified as biopharmaceutics classification system (BCS) class IV drug due to its poor solubility and permeability, resulting in low oral bioavailability. Nanostructured lipid carriers (NLC) are an
Externí odkaz:
https://doaj.org/article/f4b09b484467403ba5265832c6bce40b
Autor:
Byeong ill Lee, Min-Ho Park, Seok-Ho Shin, Jin-Ju Byeon, Yuri Park, Nahye Kim, Jangmi Choi, Young G. Shin
Publikováno v:
Molecules, Vol 24, Iss 7, p 1295 (2019)
Tozadenant is one of the selective adenosine A2a receptor antagonists with a potential to be a new Parkinson’s disease (PD) therapeutic drug. In this study, a liquid chromatography-mass spectrometry based bioanalytical method was qualified and appl
Externí odkaz:
https://doaj.org/article/be2a7fdc8c6c49d7b000afa88a53fafe
Autor:
Seok-Ho Shin, Min-Ho Park, Jin-Ju Byeon, Byeong ill Lee, Yuri Park, Nahye Kim, Jangmi Choi, Young G. Shin
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 260 (2018)
A simple and sensitive liquid chromatography⁻quadrupole-time-of-flight⁻mass spectrometric (LC-QTOF-MS) assay has been developed for the evaluation of drug metabolism and pharmacokinetics (PK) properties of vipadenant in rat, a selective A2a recep
Externí odkaz:
https://doaj.org/article/5906b70cfc7a489fa70ad5fb825cb123