Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jin-Hee Wang"'
Autor:
Thomas G. Biel, Kevin E. Behrns, Do-Sung Kim, Ivan Zendejas, Jae-Sung Kim, Joseph Flores-Toro, Jin-Hee Wang, Richa Vijayvargiya
Publikováno v:
Toxicology and Applied Pharmacology. 273:600-610
Onset of the mitochondrial permeability transition (MPT) plays a causative role in ischemia/reperfusion (I/R) injury. Current therapeutic strategies for reducing reperfusion injury remain disappointing. Autophagy is a lysosome-mediated, catabolic pro
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 302:G723-G731
Onset of the mitochondrial permeability transition (MPT) is the penultimate event leading to lethal cellular ischemia-reperfusion injury, but the mechanisms precipitating the MPT after reperfusion remain unclear. Here, we investigated the role of mit
Autor:
Wook Hwan Kim, Wankee Kim, Hyeseong Cho, Jin Hee Wang, Chawon Yun, Sujeong Kim, Sunyoung Chae, Jae-Ho Lee, Young Ik Lee
Publikováno v:
Cancer Science. 99:888-893
Multifunctional activities of the hepatitis B virus X-protein (HBx) in cells have been largely implicated in the development of liver cancer; one of these activities is the loss of p53 function by sequestering p53 in the cytoplasm. We have previously
Autor:
Chawon Yun, Jin Hee Wang, Young Hee Jin, Hyeseong Cho, Jae-Ho Lee, Hae Ryun Um, Sun Park, Mi-Ock Lee
Publikováno v:
Cancer Letters. 184:97-104
In this paper, we examined the cellular effect of hepatitits B virus X (HBx) in ChangX-34 cells, inducible HBx-expressing cells. High expression of HBx protein in ChangX-34 cells resulted in approximately three-fold increase in DNA synthesis and did
Autor:
Jae-Ho Lee, Dae Yeul Yu, Je Kyung Seong, Seung Hyun Oh, Hyeseong Cho, Jin Hee Wang, Chawon Yun
Publikováno v:
Biochemical and Biophysical Research Communications. 296:1157-1163
Hepatitis B virus (HBV) X protein (HBx) is thought to be involved in the development of liver cancer and alteration of cellular HBx level may influence the pathological progression of HBV-induced liver diseases. We found that the cellular levels of H
Autor:
Jin Hee Wang, In–Sook Ahn, Kevin E. Behrns, Jae-Sung Kim, Christiaan Leeuwenburgh, William A. Dunn, Jae–Il Byeon, Trevan D Fischer
Publikováno v:
Gastroenterology. 141(6)
Background & Aims As life expectancy increases, there are greater numbers of patients with liver diseases who require surgery or transplantation. Livers of older patients have significantly less reparative capacity following ischemia and reperfusion
Publikováno v:
Biochemical and biophysical research communications. 310(1)
HBx (hepatitis B virus X) viral oncoprotein is a multifunctional protein of which the cellular level may be one of the important factors in determining HBV-mediated pathological progression of liver diseases, chronic hepatitis, and hepatocellular car
Publikováno v:
Autophagy. 8:140-141
A steady increase in life expectancy has resulted in an equivalent increase in elderly patients who are more susceptible to diseases than young patients. In a recent study, we found that in both in vitro and in vivo models of ischemia/reperfusion (I/
Publikováno v:
World Journal of Hepatology. 6:752
AIM: To investigate the role of sorafenib (SFN) in autophagy of hepatocellular carcinoma (HCC). We evaluated how SFN affects autophagy signaling pathway in human HCC cell lines. METHODS: Two different human HCC cell lines, Hep3B and Huh7, were subjec
Publikováno v:
American Journal of Physiology: Gastrointestinal & Liver Physiology; Apr2012, Vol. 302 Issue 4, pG723-G731, 10p