Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Jin-Feng Teng"'
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Akademický článek
Targeting microglial autophagic degradation of the NLRP3 inflammasome for identification of thonningianin A in Alzheimer’s disease
Autor: Xiao-Gang Zhou, Wen-Qiao Qiu, Lu Yu, Rong Pan, Jin-Feng Teng, Zhi-Pei Sang, Betty Yuen-Kwan Law, Ya Zhao, Li Zhang, Lu Yan, Yong Tang, Xiao-Lei Sun, Vincent Kam Wai Wong, Chong-Lin Yu, Jian-Ming Wu, Da-Lian Qin, An-Guo Wu
Publikováno v: Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-25 (2022)
Abstract Background NLRP3 inflammasome-mediated neuroinflammation plays a critical role in the pathogenesis and development of Alzheimer’s disease (AD). Microglial autophagic degradation not only decreases the deposits of extracellular Aβ fibrils
Externí odkaz: https://doaj.org/article/18737a8c81c4472581e4f0c99e7cbaf2
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3
Lychee seed polyphenol protects the blood–brain barrier through inhibiting Aβ(25–35)‐induced NLRP3 inflammasome activation via the AMPK / mTOR / ULK1‐mediated autophagy in bEnd .3 cells and APP / PS1 mice
Autor: Liu Sha, Rong Pan, Qibing Mei, Yong Tang, Xiao-Gang Zhou, Yi-Ling Wang, Ya Zhao, Wen-Qiao Qiu, Betty Yuen Kwan Law, Yueshan Sun, Jin-Feng Teng, Rui Xiong, Dalian Qin, Xiuling Wang, Jianming Wu, Lu Yu, Chong-Lin Yu, An-Guo Wu
Publikováno v: Phytotherapy Research. 35:954-973
Blood-brain barrier (BBB) dysfunction has been implicated in Alzheimer's disease (AD) and is closely linked to the release of proinflammatory cytokines in brain capillary endothelial cells. We have previously reported that lychee seed polyphenols (LS
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9012b0c03a9a89534c36fd5fc4cb029
https://doi.org/10.1002/ptr.6849
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4
Lychee seed polyphenol protects the blood-brain barrier through inhibiting Aβ(25-35)-induced NLRP3 inflammasome activation via the AMPK/mTOR/ULK1-mediated autophagy in bEnd.3 cells and APP/PS1 mice
Autor: Rui, Xiong, Xiao-Gang, Zhou, Yong, Tang, Jian-Ming, Wu, Yue-Shan, Sun, Jin-Feng, Teng, Rong, Pan, Betty Yuen-Kwan, Law, Ya, Zhao, Wen-Qiao, Qiu, Xiu-Ling, Wang, Sha, Liu, Yi-Ling, Wang, Lu, Yu, Chong-Lin, Yu, Qi-Bing, Mei, Da-Lian, Qin, An-Guo, Wu
Publikováno v: Phytotherapy research : PTRREFERENCES. 35(2)
Blood-brain barrier (BBB) dysfunction has been implicated in Alzheimer's disease (AD) and is closely linked to the release of proinflammatory cytokines in brain capillary endothelial cells. We have previously reported that lychee seed polyphenols (LS
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62687868efa447995726f9de819d3a01
https://pubmed.ncbi.nlm.nih.gov/32893437
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5
Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer
Autor: Ya Zhao, Wen-Qiao Qiu, Yong Tang, Chong-Lin Yu, Rui Xiong, An-Guo Wu, Betty Yuen Kwan Law, Jin-Feng Teng, Dalian Qin, Rong Pan, Feng Zhang, Jianming Wu, Vincent Kam Wai Wong, Qibing Mei
Publikováno v: Pharmacological research. 147
Non-small cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancers. Our previous studies have proven that Trillium tschonoskii Maxim. (TTM), a traditional Chinese medicine, possesses potent anti-tumor effect. However, the detailed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa56a0cfa5dc09e7490790f2351ea83a
https://pubmed.ncbi.nlm.nih.gov/31404628
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6
Polyphenols isolated from lychee seed inhibit Alzheimer's disease-associated Tau through improving insulin resistance via the IRS-1/PI3K/Akt/GSK-3β pathway
Autor: Haixia Chen, An-Guo Wu, Yong Tang, Wen-Qiao Qiu, Rong Pan, Rui Xiong, Jin-Feng Teng, Xin Shen, Dalian Qin, Ya Zhao, Jianming Wu, Xiuling Wang, Jian Liu, Lu Yu, Chong-Lin Yu
Publikováno v: Journal of ethnopharmacology. 251
Ethnopharmacological relevance Lychee seed, the seed of Litchi chinensis Sonn. is one of the commonly used in traditional Chinese medicine (TCM). It possesses many pharmacological effects such as blood glucose and lipid-lowering effects, liver protec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab539829661d40a534d69b095b7e5b3
https://pubmed.ncbi.nlm.nih.gov/31917277
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7
Novel steroidal saponin isolated from Trillium tschonoskii maxim. exhibits anti-oxidative effect via autophagy induction in cellular and Caenorhabditis elegans models
Autor: Rong Pan, Lu Yu, Betty Yuen Kwan Law, Yong Tang, An-Guo Wu, Yi-Ling Wang, Bin Tang, Wen-Qiao Qiu, Xiao-Gang Zhou, Rui Xiong, Tian-Yi Ding, Dalian Qin, Wu Zeng, Jin-Feng Teng, Jianming Wu, Vincent Kam Wai Wong
Publikováno v: Phytomedicine : international journal of phytotherapy and phytopharmacology. 65
Background Emerging evidences indicate the important roles of autophagy in anti-oxidative stress, which is closely associated with cancer, aging and neurodegeneration. Objective In the current study, we aimed to identify autophagy inducers with poten
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b7b88b2e6c89c30965c5286541f837
https://pubmed.ncbi.nlm.nih.gov/31627105
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8
Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer
Autor: Yong Tang, Dalian Qin, Betty Yuen Kwan Law, Han-An Long, Rong Pan, Chong-Lin Yu, Rui Xiong, An-Guo Wu, Jianming Wu, Xiao-Gang Zhou, Xiu-Li Xiao, Vincent Kam Wai Wong, Qibing Mei, Jin-Feng Teng, Wen-Qiao Qiu, Feng Zhang
Publikováno v: Cancers, Vol 12, Iss 1, p 193 (2020)
Cancers
Volume 12
Issue 1
Trillium tschonoskii Maxim (TTM), a traditional Chinese medicine, has been demonstrated to have a potent anti-tumor effect. Recently, polyphyllin VI (PPVI), a main saponin isolated from TTM, was reported by us to significantly suppress the proliferat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8a334ae4d1e0861e4cd2a322f2d838
https://doi.org/10.3390/cancers12010193
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9
Polyphenols Derived from Lychee Seed Suppress Aβ (1-42)-Induced Neuroinflammation
Autor: Yong Tang, Jianming Wu, Dalian Qin, Ya Zhao, Wen-Qiao Qiu, Haixia Chen, An-Guo Wu, Rui Xiong, Xiuling Wang, Jin-Feng Teng, Chong-Lin Yu, Jian Liu
Publikováno v: International Journal of Molecular Sciences, Vol 19, Iss 7, p 2109 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 7
Amyloid-&beta
(A&beta
) is commonly recognized as the most important factor that results in neuronal cell death and accelerates the progression of Alzheimer&rsquo
s disease (AD). Increasing evidence suggests that microglia activated by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4533488eda6f312f6c99b96dd3349d2
http://www.mdpi.com/1422-0067/19/7/2109
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