Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Jin-Ah Park"'
Autor:
Megan E. Solan, Jin-Ah Park
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Per- and poly-fluoroalkyl substances (PFAS) are a broad class of synthetic compounds widely used in commercial applications. The persistent nature of PFAS in the environment has earned them the epithet “forever chemicals.” Concerns arise from wid
Externí odkaz:
https://doaj.org/article/976ab384ade242c9b0123b6e89037cdb
Autor:
Alane Blythe C. Dy, Jason Girkin, Antonella Marrocco, Adam Collison, Chimwemwe Mwase, Michael J. O’Sullivan, Thien-Khoi N. Phung, Joerg Mattes, Cynthia Koziol-White, James E. Gern, Yury A. Bochkov, Nathan W. Bartlett, Jin-Ah Park
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Rhinovirus (RV) infection of airway epithelial cells triggers asthma exacerbations, during which airway smooth muscle (ASM) excessively contracts. Due to ASM contraction, airway epithelial cells become mechanically compressed. We
Externí odkaz:
https://doaj.org/article/6d91833041f34be599ab4fc5a6112907
Publikováno v:
Biology Open, Vol 12, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/23e0dcf803d841e4a1eac89973558412
Autor:
Hae-Ryung Park, Jose Vallarino, Michael O’Sullivan, Charlotte Wirth, Ronald A. Panganiban, Gabrielle Webb, Maya Shumyatcher, Blanca E. Himes, Jin-Ah Park, David C. Christiani, Joseph Allen, Quan Lu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The widespread use of electronic cigarettes (e-cig) is a serious public health concern; however, mechanisms by which e-cig impair the function of airway epithelial cells—the direct target of e-cig smoke—are not fully understood. Here we
Externí odkaz:
https://doaj.org/article/e98fd73566834d71945540b957f89298
Autor:
Ian T. Stancil, Jacob E. Michalski, Duncan Davis-Hall, Hong Wei Chu, Jin-Ah Park, Chelsea M. Magin, Ivana V. Yang, Bradford J. Smith, Evgenia Dobrinskikh, David A. Schwartz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Environmental and genetic risk factors affect the distal airway epithelium in idiopatic pulmonary fibrosis (IPF) but the role of the epithelium in IPF remains unclear. Here the authors show that pathologic activation of the ERBB-YAP axis induces dyna
Externí odkaz:
https://doaj.org/article/01dae7f647b5461cb308f23c36fac345
Autor:
Jennifer A. Mitchel, Amit Das, Michael J. O’Sullivan, Ian T. Stancil, Stephen J. DeCamp, Stephan Koehler, Oscar H. Ocaña, James P. Butler, Jeffrey J. Fredberg, M. Angela Nieto, Dapeng Bi, Jin-Ah Park
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
During repair, development, or cancer metastasis, epithelial cells can become migratory through partial or full epithelial to mesenchymal transition (EMT). Here, the authors report that differentiated epithelial collectives may undergo cooperative an
Externí odkaz:
https://doaj.org/article/ab4af25389c54c6284d0fdfba0eb6c62
Autor:
Minmin Hou, Junwen Han, Gu Li, Min-Young Kwon, Jiani Jiang, Sirisha Emani, Elizabeth S. Taglauer, Jin-Ah Park, Eun-Bee Choi, Munender Vodnala, Yick W. Fong, Sitaram M. Emani, Ivan O. Rosas, Mark A. Perrella, Xiaoli Liu
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-13 (2020)
Abstract Background In a number of disease processes, the body is unable to repair injured tissue, promoting the need to develop strategies for tissue repair and regeneration, including the use of cellular therapeutics. Trophoblast stem cells (TSCs)
Externí odkaz:
https://doaj.org/article/9346d3a4c16d46538ae9063a1e6593cf
Autor:
Wenying Kang, Jacopo Ferruzzi, Catalina-Paula Spatarelu, Yu Long Han, Yasha Sharma, Stephan A. Koehler, Jennifer A. Mitchel, Adil Khan, James P. Butler, Darren Roblyer, Muhammad H. Zaman, Jin-Ah Park, Ming Guo, Zi Chen, Adrian F. Pegoraro, Jeffrey J. Fredberg
Publikováno v:
iScience, Vol 24, Iss 11, Pp 103252- (2021)
Summary: It is well established that the early malignant tumor invades surrounding extracellular matrix (ECM) in a manner that depends upon material properties of constituent cells, surrounding ECM, and their interactions. Recent studies have establi
Externí odkaz:
https://doaj.org/article/940b9644a5384a00ab965aa9bfe5e056
Publikováno v:
Open Biology, Vol 10, Iss 12 (2020)
In asthma, progressive structural changes of the airway wall are collectively termed airway remodelling. Despite its deleterious effect on lung function, airway remodelling is incompletely understood. As one of the important causes leading to airway
Externí odkaz:
https://doaj.org/article/dd4b0b4559c2478f9f1a55e66237d3bd
Autor:
Punnam Chander Veerati, Jennifer A. Mitchel, Andrew T. Reid, Darryl A. Knight, Nathan W. Bartlett, Jin-Ah Park, Chris L. Grainge
Publikováno v:
European Respiratory Review, Vol 29, Iss 157 (2020)
The lung is a mechanically active organ, but uncontrolled or excessive mechanical forces disrupt normal lung function and can contribute to the development of disease. In asthma, bronchoconstriction leads to airway narrowing and airway wall buckling.
Externí odkaz:
https://doaj.org/article/e4382b1a84d54c40bb9de663c3c71d81