Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jin Yuan Fan"'
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
The sensitivity of the eye at night would lead to complete saturation of the eye during the day. Therefore, the sensitivity of the eye must be down-regulated during the day to maintain visual acuity. In the Drosophila eye, the opening of TRP and TRPL
Externí odkaz:
https://doaj.org/article/1464eac65af54302a994d0e43861ad69
Autor:
Richard Brent Nolan, Colleen Bontrager, Abigail Bowser, Alyssa Corley, Hana Fiedler, Connor Flathers, Lauren Francis, Angel Le, Seyyed Mahmoudjafari, Tinh Nim, Connor E. Muolo, Brianna Shores, Christopher Viermann, Adam Waldren, Carmen Zatezalo, Jin-Yuan Fan, Jeffrey L. Price
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106343- (2023)
Summary: BRIDE OF DOUBLETIME (BDBT) interacts with the circadian kinase DOUBLETIME (DBT) and accumulates in eye foci during the dark of a light:dark cycle. BDBT foci are shown here to be broadly expressed in constant dark and low in constant light. A
Externí odkaz:
https://doaj.org/article/6bbc7b064b344b419dbc93dcb29a2119
Publikováno v:
Frontiers in Neuroscience; 2024, p1-6, 6p
Publikováno v:
PLoS Genetics, Vol 18, Iss 2 (2022)
Sleep is a very important behavior observed in almost all animals. Importantly, sleep is subject to both circadian and homeostatic regulation. The circadian rhythm determines the daily alternation of the sleep-wake cycle, while homeostasis mediates t
Externí odkaz:
https://doaj.org/article/679f0b93b47440469aae22d0fc98d41e
Autor:
Zachary Fischer, Rahul Das, Anna Shipman, Jin-Yuan Fan, Laramie Pence, Samuel Bouyain, Leonard L. Dobens
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 12, Pp 1453-1464 (2017)
Members of the Tribbles family of proteins are conserved pseudokinases with diverse roles in cell growth and proliferation. Both Drosophila Tribbles (Trbl) and vertebrate Trib3 proteins bind to the kinase Akt (Akt1) to block its phosphorylation activ
Externí odkaz:
https://doaj.org/article/d3c6e48b555d4172866b23378da37140
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 4, p 813 (2019)
Drosophila Double-time (DBT) phosphorylates the circadian protein Period (PER). The period-altering mutation tau, identified in hamster casein kinase I (CKIε) and created in Drosophila DBT, has been shown to shorten the circadian period in flies, as
Externí odkaz:
https://doaj.org/article/2ad6f47cbbac442cafcf5a12c3330be3
Autor:
John C Means, Anandakrishnan Venkatesan, Bryan Gerdes, Jin-Yuan Fan, Edward S Bjes, Jeffrey L Price
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005171 (2015)
While circadian dysfunction and neurodegeneration are correlated, the mechanism for this is not understood. It is not known if age-dependent circadian dysfunction leads to neurodegeneration or vice-versa, and the proteins that mediate the effect rema
Externí odkaz:
https://doaj.org/article/0c1f0a8e419f46608fe5109ea658c0d1
Publikováno v:
PLoS Genetics, Vol 18, Iss 2 (2022)
PLoS Genetics, Vol 18, Iss 2, p e1010035 (2022)
PLoS Genetics, Vol 18, Iss 2, p e1010035 (2022)
Sleep is a very important behavior observed in almost all animals. Importantly, sleep is subject to both circadian and homeostatic regulation. The circadian rhythm determines the daily alternation of the sleep-wake cycle, while homeostasis mediates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566b8df11b44a59f87eaf95eb24a41d7
https://pubmed.ncbi.nlm.nih.gov/35139068
https://pubmed.ncbi.nlm.nih.gov/35139068
Autor:
Richard Brent Nolan, Hana Fiedler, Connor Muolo, Colleen Bontrager, Brianna Shores, Angel Le, Jin-Yuan Fan, Jeffrey L. Price, Abigail Bowser, Lauren Francis, Carmen Zatezalo, Seyyed Mahmoudjafari, Connor Flathers
Publikováno v:
SSRN Electronic Journal.
BDBT interacts with the circadian kinase DBT and accumulates in eye foci during the dark of a light:dark cycle. BDBT is shown here to be constitutively high in the dark and constitutively low in the light. Analysis of circadian photoreceptor cry and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652b6dfba935ad83f3c80450d90863dc
https://doi.org/10.2139/ssrn.3932607
https://doi.org/10.2139/ssrn.3932607
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 4, p 813 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 4
International Journal of Molecular Sciences
Volume 20
Issue 4
Drosophila Double-time (DBT) phosphorylates the circadian protein Period (PER). The period-altering mutation tau, identified in hamster casein kinase I (CKI&epsilon
) and created in Drosophila DBT, has been shown to shorten the circadian period
) and created in Drosophila DBT, has been shown to shorten the circadian period
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c259ab47d382d8d5703bb3f0ca8eee5
https://www.mdpi.com/1422-0067/20/4/813
https://www.mdpi.com/1422-0067/20/4/813