Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jin Yan Yap"'
Autor:
Leslie Burnett, John Reeves, Cindy S. Ma, Jennifer Stoddard, William A. Figgett, Helen C. Su, Jin Yan Yap, Gulbu Uzel, Huie Jing, Jane Peake, Paul Gray, Anna Sullivan, Bethany Pillay, Sarah K. Kummerfeld, Stuart G. Tangye, Dianne E. Campbell
Publikováno v:
Journal of Clinical Immunology. 42:119-129
Rare, biallelic loss-of-function mutations in DOCK8 result in a combined immune deficiency characterized by severe and recurrent cutaneous infections, eczema, allergies, and susceptibility to malignancy, as well as impaired humoral and cellular immun
Autor:
Giorgia Bucciol, Cindy S. Ma, Ming-Wei Lin, Jin Yan Yap, Anthony D. Kelleher, Leen Moens, Georgina E Hollway, Isabelle Meyts, Michael S. Hershfield, Kathy H C Wu, Paul Gray, William A. Sewell, Stuart G. Tangye, Karen Enthoven, Alisa Kane, Jose Casas-Martin, Tri Giang Phan, Selket Delafontaine, Lien De Somer, Catherine Toong, Carine Wouters
Publikováno v:
Journal of Clinical Immunology
Journal of Clinical Immunology, volume 41, pages1915–1935 (2021)
Journal of Clinical Immunology, volume 41, pages1915–1935 (2021)
Purpose Deficiency of adenosine deaminase type 2 (ADA2) (DADA2) is a rare inborn error of immunity caused by deleterious biallelic mutations in ADA2. Clinical manifestations are diverse, ranging from severe vasculopathy with lacunar strokes to immuno
Autor:
Nathan W. Zammit, Paul E. Gray, Owen M. Siggs, Jin Yan Yap, Amanda Russell, Daniele Cultrone, Joanna Warren, Stacey N. Walters, Robert Brink, David Zahra, Deborah L. Burnett, Velimir Gayevskiy, Andre E. Minoche, John B. Ziegler, Maria E. Craig, Melanie Wong, Paul Benitez-Aguirre, Juliana Teo, Mark J. Cowley, Marcel E. Dinger, Stuart G. Tangye, Catherine Burke, Tri G. Phan, Christopher C. Goodnow, Shane T. Grey
Monogenic diseases can often manifest diverse clinical phenotypes and cause diagnostic dilemmas. While monoallelic loss-of-function variants in TNFAIP3 (Haploinsufficiency of A20; HA20) cause a highly penetrant autoinflammatory disease, the variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7578a43b8a1ded2a2635d1cf7fc5bbe6
https://doi.org/10.1101/2022.03.19.485004
https://doi.org/10.1101/2022.03.19.485004
Autor:
Stuart G, Tangye, Paul E, Gray, Bethany A, Pillay, Jin Yan, Yap, William A, Figgett, John, Reeves, Sarah K, Kummerfeld, Jennifer, Stoddard, Gulbu, Uzel, Huie, Jing, Helen C, Su, Dianne E, Campbell, Anna, Sullivan, Leslie, Burnett, Jane, Peake, Cindy S, Ma
Publikováno v:
Journal of clinical immunology. 42(1)
Rare, biallelic loss-of-function mutations in DOCK8 result in a combined immune deficiency characterized by severe and recurrent cutaneous infections, eczema, allergies, and susceptibility to malignancy, as well as impaired humoral and cellular immun
Autor:
Robert Brink, David Zahra, Jeanette E. Villanueva, Benjamin T. Porebski, Garry P. Nolan, Murray P. Cox, Carla M. Roots, Claudia Loetsch, Cecile King, Paul Z. Benitez-Aguirre, Jia Tang, Belinda Whittle, Juliana Teo, Joanna Warren, Wendy Sandoval, Marcel E. Dinger, Elisabeth K. Malle, Christopher C. Goodnow, Geeta Chaudhri, Velimir Gayevskiy, Ingrid E. Wertz, Jin Yan Yap, John B. Ziegler, Yogesh Jeelall, Keisuke Horikawa, Colin J. Jackson, Stacey N. Walters, Daniele Cultrone, Daniel Christ, Frank Schmitz, Nathan W. Zammit, Shane T. Grey, Melanie Wong, David B. Langley, Craig N. Jenne, Owen M. Siggs, Tim Wiltshire, Anselm Enders, Lewis L. Lanier, Mark J. Cowley, Matthew H. Spitzer, Wilson Phung, Stuart G. Tangye, Peter D. Mabbitt, Derek W. Abbott, Susan R. Watson, Benjamin E. Clifton, Stephen R. Daley, Alan Aderem, Paul Gray, Ashley M. Buckle, Gunasegaran Karupiah, Michiko Yamada, Edward M. Bertram, Amanda J. Russell, Maria E. Craig
Publikováno v:
Nature Immunology. 20:1299-1310
Resisting and tolerating microbes are alternative strategies to survive infection, but little is known about the evolutionary mechanisms controlling this balance. Here genomic analyses of anatomically modern humans, extinct Denisovan hominins and mic
Autor:
Stephen R. Daley, Christopher C. Goodnow, Daniel Y. Hu, Charis E Teh, Jin Yan Yap, Daniel H.D. Gray, Rushika C. Wirasinha, Anna Chan
Publikováno v:
Cell Death Differ
The selection of αβ T cells in the thymus is punctuated by checkpoints at which thymocytes differentiate or undergo apoptosis. Wave 1 deletion is defined as apoptosis within nascent αβ T-cell antigen receptor (TCR)-signalled thymocytes that lack
Autor:
Mark N. Polizzotto, Stuart G. Tangye, Edwin Kirk, Andrew Parker, Pei Dai, Lucinda J. Berglund, Brian S. Gloss, Eric Wegman, Jin Yan Yap, Vickie Marshall, Marcel Batten, Circa, Wendell Miley, Min Qiu, Tri Giang Phan, Roger Garsia, Peter Hsu, Elissa K. Deenick, Fenfen Cai, Romin Roshan, Cindy S. Ma, Denise Whitby, Kathy H C Wu
Publikováno v:
J Clin Immunol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab97adacd0abc2020f5457bd2d876bf
https://europepmc.org/articles/PMC8996434/
https://europepmc.org/articles/PMC8996434/
Autor:
Nathan W, Zammit, Owen M, Siggs, Paul E, Gray, Keisuke, Horikawa, David B, Langley, Stacey N, Walters, Stephen R, Daley, Claudia, Loetsch, Joanna, Warren, Jin Yan, Yap, Daniele, Cultrone, Amanda, Russell, Elisabeth K, Malle, Jeanette E, Villanueva, Mark J, Cowley, Velimir, Gayevskiy, Marcel E, Dinger, Robert, Brink, David, Zahra, Geeta, Chaudhri, Gunasegaran, Karupiah, Belinda, Whittle, Carla, Roots, Edward, Bertram, Michiko, Yamada, Yogesh, Jeelall, Anselm, Enders, Benjamin E, Clifton, Peter D, Mabbitt, Colin J, Jackson, Susan R, Watson, Craig N, Jenne, Lewis L, Lanier, Tim, Wiltshire, Matthew H, Spitzer, Garry P, Nolan, Frank, Schmitz, Alan, Aderem, Benjamin T, Porebski, Ashley M, Buckle, Derek W, Abbott, John B, Ziegler, Maria E, Craig, Paul, Benitez-Aguirre, Juliana, Teo, Stuart G, Tangye, Cecile, King, Melanie, Wong, Murray P, Cox, Wilson, Phung, Jia, Tang, Wendy, Sandoval, Ingrid E, Wertz, Daniel, Christ, Christopher C, Goodnow, Shane T, Grey
Publikováno v:
Nature immunology. 20(10)
Resisting and tolerating microbes are alternative strategies to survive infection, but little is known about the evolutionary mechanisms controlling this balance. Here genomic analyses of anatomically modern humans, extinct Denisovan hominins and mic
Autor:
Debbie R. Howard, Stephen R. Daley, Rushika C. Wirasinha, Jin Yan Yap, Anna Chan, Christopher C. Goodnow
Acquisition of T‐cell central tolerance involves distinct pathways of self‐antigen presentation to thymocytes. One pathway termed indirect presentation requires a self‐antigen transfer step from thymic epithelial cells (TECs) to bone marrow‐d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c921d0ad4016686c5979c3f8fdbef6a2
https://europepmc.org/articles/PMC6002238/
https://europepmc.org/articles/PMC6002238/