Copper-Catalyzed [3 + 2] Annulation of O -Acyl Oximes with p -Hydroquinones for the Synthesis of 5-Hydroxyindoles.

Autor: Zhang HP; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Chen W; Changzhou Siyao Pharmaceuticals Co., Ltd., Changzhou, Jiangsu 213018, China., Hu ZJ; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Lyu X; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Qiao EJ; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Jin WB; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Xu WY; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Ding XH; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Miao CB; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China., Yang HT; School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology, Changzhou University, Changzhou, Jiangsu 213164, China.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2024 Oct 18; Vol. 89 (20), pp. 14968-14980. Date of Electronic Publication: 2024 Oct 04.

Functional characterization of helminth-associated Clostridiales reveals covariates of Treg differentiation.

Autor: Sargsian S; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, 10016, USA., Mondragón-Palomino O; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA., Lejeune A; Department of Microbiology, New York University Grossman School of Medicine, New York, NY, 10016, USA., Ercelen D; Department of Medicine, Division of Gastroenterology and Hepatology, New York University Langone Health, New York, NY, 10016, USA., Jin WB; Weill Cornell Medicine, Jill Roberts Institute for Research in Inflammatory Bowel Disease, Cornell University, New York, NY, 10021, USA., Varghese A; Department of Cell Biology, New York University Grossman School of Medicine, New York, NY, 10016, USA., Lim YAL; Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, 50603, Malaysia., Guo CJ; Weill Cornell Medicine, Jill Roberts Institute for Research in Inflammatory Bowel Disease, Cornell University, New York, NY, 10021, USA., Loke P; Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, 20892, USA. png.loke@nih.gov., Cadwell K; Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. ken.cadwell@pennmedicine.upenn.edu.; Department of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. ken.cadwell@pennmedicine.upenn.edu.; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. ken.cadwell@pennmedicine.upenn.edu.

Publikováno v: Microbiome [Microbiome] 2024 May 10; Vol. 12 (1), pp. 86. Date of Electronic Publication: 2024 May 10.

Dietary fiber is a critical determinant of pathologic ILC2 responses and intestinal inflammation.

Autor: Arifuzzaman M; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Won TH; Department of Chemistry and Chemical Biology, Boyce Thompson Institute, Cornell University, Ithaca, NY, USA., Yano H; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Uddin J; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Emanuel ER; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, Cornell University , New York, NY, USA., Hu E; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Zhang W; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Li TT; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Jin WB; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Grier A; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Kashyap S; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Guo CJ; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Schroeder FC; Department of Chemistry and Chemical Biology, Boyce Thompson Institute, Cornell University, Ithaca, NY, USA., Artis D; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Immunology and Microbial Pathogenesis Program, Weill Cornell Medicine, Cornell University , New York, NY, USA.; Allen Discovery Center for Neuroimmune Interactions, New York, NY, USA.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2024 May 06; Vol. 221 (5). Date of Electronic Publication: 2024 Mar 20.

The gut microbiome regulates the clinical efficacy of sulfasalazine therapy for IBD-associated spondyloarthritis.

Autor: Lima SF; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Pires S; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Rupert A; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA; Jill Roberts Center for IBD, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Oguntunmibi S; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Jin WB; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA., Marderstein A; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA., Funez-dePagnier G; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA; Jill Roberts Center for IBD, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Maldarelli G; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Viladomiu M; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Putzel G; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA., Yang W; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Tran N; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA; Jill Roberts Center for IBD, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Xiang G; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA; Jill Roberts Center for IBD, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Grier A; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA., Guo CJ; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA., Lukin D; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA; Jill Roberts Center for IBD, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Mandl LA; Division of Rheumatology, Hospital for Special Surgery and Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Scherl EJ; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA; Jill Roberts Center for IBD, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA., Longman RS; Jill Roberts Institute for Research in IBD, Weill Cornell Medicine, New York, NY 10065, USA; Division of Gastroenterology and Hepatology, Department of Medicine, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA; Jill Roberts Center for IBD, NewYork-Presbyterian Hospital/Weill Cornell Medical Center, New York, NY 10065, USA. Electronic address: ral2006@med.cornell.edu.

Publikováno v: Cell reports. Medicine [Cell Rep Med] 2024 Mar 19; Vol. 5 (3), pp. 101431. Date of Electronic Publication: 2024 Feb 19.

Inulin fibre promotes microbiota-derived bile acids and type 2 inflammation.

Autor: Arifuzzaman M; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Won TH; Boyce Thompson Institute, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA., Li TT; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Yano H; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Digumarthi S; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Heras AF; Gale and Ira Drukier Institute for Children's Health, Department of Pediatrics, Weill Cornell Medicine, Cornell University, New York, NY, USA., Zhang W; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Parkhurst CN; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Kashyap S; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Jin WB; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Putzel GG; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Tsou AM; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Weill Cornell Medicine, New York, NY, USA., Chu C; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Wei Q; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Grier A; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA., Worgall S; Gale and Ira Drukier Institute for Children's Health, Department of Pediatrics, Weill Cornell Medicine, Cornell University, New York, NY, USA., Guo CJ; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA. chg4001@med.cornell.edu.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA. chg4001@med.cornell.edu.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA. chg4001@med.cornell.edu., Schroeder FC; Boyce Thompson Institute, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA. schroeder@cornell.edu., Artis D; Jill Roberts Institute for Research in Inflammatory Bowel Disease, Division of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY, USA. dartis@med.cornell.edu.; Friedman Center for Nutrition and Inflammation, Weill Cornell Medicine, Cornell University, New York, NY, USA. dartis@med.cornell.edu.; Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, NY, USA. dartis@med.cornell.edu.

Publikováno v: Nature [Nature] 2022 Nov; Vol. 611 (7936), pp. 578-584. Date of Electronic Publication: 2022 Nov 02.