Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Jin Sook, Song"'
Publikováno v:
BMC Neuroscience, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Several phosphodiesterase 4 (PDE4) inhibitors have emerged as potential therapeutics for central nervous system (CNS) diseases. This study investigated the pharmacological effects of two selective PDE4 inhibitors, roflumilast and
Externí odkaz:
https://doaj.org/article/4b7d62c2fa5d4890b4ef50d769a9434b
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3532-3539 (2023)
Stability of compounds in the human plasma is crucial for maintaining sufficient systemic drug exposure and considered an essential factor in the early stages of drug discovery and development. The rapid degradation of compounds in the plasma can res
Externí odkaz:
https://doaj.org/article/bd4d78c3b6b540fa9bbc02740bd52450
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 2320-2329 (2022)
Dimerized translationally controlled tumor protein (dTCTP) initiates a variety of allergic responses in mouse models and that dTCTP-binding peptide 2 (dTBP2) attenuates the allergic inflammation by targeting dTCTP. However, the usefulness of peptide-
Externí odkaz:
https://doaj.org/article/540b00f3da5f468397d18edf560d8a92
The KDM4B–CCAR1–MED1 axis is a critical regulator of osteoclast differentiation and bone homeostasis
Autor:
Sun-Ju Yi, You-Jee Jang, Hye-Jung Kim, Kyubin Lee, Hyerim Lee, Yeojin Kim, Junil Kim, Seon Young Hwang, Jin Sook Song, Hitoshi Okada, Jae-Il Park, Kyuho Kang, Kyunghwan Kim
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Bone undergoes a constant and continuous remodeling process that is tightly regulated by the coordinated and sequential actions of bone-resorbing osteoclasts and bone-forming osteoblasts. Recent studies have shown that histone demethylases a
Externí odkaz:
https://doaj.org/article/084606c8aaa04b1d92d1384ba719d49e
Publikováno v:
Nutrients, Vol 14, Iss 22, p 4757 (2022)
Succinic acid is widely used as a food additive, and its effects on sepsis, cancer, ataxia, and obesity were recently reported. Dietary drug exposure studies have been conducted to evaluate the in vivo efficacy of succinic acid, but limited pharmacok
Externí odkaz:
https://doaj.org/article/f9190a329fa549f28fc09d953e06b39e
Autor:
Ho Joong Choi, Suk Joon Cho, Ok-Hee Kim, Jin Sook Song, Ha-Eun Hong, Sang Chul Lee, Kee-Hwan Kim, Sang Kuon Lee, Young Kyoung You, Tae Ho Hong, Eun Young Kim, Jung Hyun Park, Gun Hyung Na, Dong Do You, Jae Hyun Han, Jae Woo Park, Bong Jun Kwak, Tae Yun Lee, Joseph Ahn, Hwan Hee Lee, Seung Kyu Kang, Kyu-Seok Hwang, Jae-Kyung Jung, Kwan-Young Jung, Say-June Kim
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Although methyl-tertiary butyl ether (MTBE) is the only clinical topical agent for gallstone dissolution, its use is limited by its side effects mostly arising from a relatively low boiling point (55 °C). In this study, we develo
Externí odkaz:
https://doaj.org/article/cae19a5cb78244229e3cfe761383420c
Autor:
Suvarna H. Pagire, Haushabhau S. Pagire, Kun-Young Park, Eun Jung Bae, Kwang-eun Kim, Minhee Kim, Jihyeon Yoon, Saravanan Parameswaran, Jun-Ho Choi, Sungmi Park, Jae-Han Jeon, Jin Sook Song, Myung Ae Bae, In-Kyu Lee, Hail Kim, Jae Myoung Suh, Jin Hee Ahn
Publikováno v:
Molecules, Vol 27, Iss 11, p 3417 (2022)
Serotonin (5-hydroxytryptophan) is a hormone that regulates emotions in the central nervous system. However, serotonin in the peripheral system is associated with obesity and fatty liver disease. Because serotonin cannot cross the blood-brain barrier
Externí odkaz:
https://doaj.org/article/a8bd683ccb2944e9ae9b9c975275701f
Autor:
Ji Hun, Lee, Sang Hee, Ji, Jong Seung, Lim, Sunjoo, Ahn, Hwi-Yeol, Yun, Seong Hwan, Kim, Jin Sook, Song
Publikováno v:
Neurochemical Research. 47:3829-3837
Selonsertib is a first-in-class apoptosis signal-regulating kinase 1 (ASK1) inhibitor in clinical trials for treating NASH and diabetic kidney disease due to its anti-inflammatory and anti-fibrotic activities. In the present study, we investigated th
Autor:
Sang Chul Lee, Tae Ho Hong, Ok-Hee Kim, Suk Joon Cho, Kee-Hwan Kim, Jin Sook Song, Kyu-Seok Hwang, Jae-Kyung Jung, Ha-Eun Hong, Haeyeon Seo, Ho Joong Choi, Joseph Ahn, Tae Yoon Lee, Eunyoung Rim, Kwan-Young Jung, Say-June Kim
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5, p 1759 (2020)
This paper aims to validate if intrapancreatic injection of penicillin G can enhance hardness and suture holding capacity (SHC) of the pancreas through prompting the fibrosis process. Soft pancreatic texture is constantly mentioned as one of the most
Externí odkaz:
https://doaj.org/article/ced27816614847c492a91e65aa262de3
Autor:
Ji Hun Lee, Sang Hee Ji, Jong Seung Lim, Sunjoo Ahn, Hwi-yeol Yun, Seong Hwan Kim, Jin Sook Song
Selonsertib is a first-in-class apoptosis signal-regulating kinase 1 (ASK1) inhibitor that was in clinical trials for treatment of NASH and diabetic kidney disease due to its anti-inflammatory and anti-fibrotic activities. In the present study, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ad94135cc37ce57146f31c813b68199
https://doi.org/10.21203/rs.3.rs-1951391/v1
https://doi.org/10.21203/rs.3.rs-1951391/v1