Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Jin Ryoun Kim"'
Autor:
Jin Ryoun Kim
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Aberrant self-assembly of an intrinsically disordered protein is a pathological hallmark of protein misfolding diseases, such as Alzheimer’s and Parkinson’s diseases (AD and PD, respectively). In AD, the 40–42 amino acid-long extracellular pept
Externí odkaz:
https://doaj.org/article/d7c3992e01fe45698a4b6cd053552208
Autor:
Anthony J. Finch, Jin Ryoun Kim
Publikováno v:
Microorganisms, Vol 6, Iss 4, p 97 (2018)
Literature from the past two decades has outlined the existence of a trade-off between protein stability and function. This trade-off creates a unique challenge for protein engineers who seek to introduce new functionality to proteins. These engineer
Externí odkaz:
https://doaj.org/article/9660b1ec7cad4a47829a59171c9f57f0
Publikováno v:
Biochem Biophys Res Commun
Parkinson's disease (PD) is linked to the aberrant self-assembly of the amyloid protein, α-synuclein (αS), where αS monomers aggregate to form oligomers and fibrils. Out of the three conformers, αS oligomers are the major toxic agents in PD, whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1007c083ad6bccbb15f34745cec1987
https://doi.org/10.1016/j.bbrc.2021.08.049
https://doi.org/10.1016/j.bbrc.2021.08.049
Autor:
Kwanghee Lee, Dong Young Kim, Edward Chau, Juan Meng, Jaemin Kong, Francisco Antonio, Tai De Li, Yongwoo Shin, Sooncheol Kwon, Adlai Katzenberg, Hailiang Wang, Yueshen Wu, Jason A. Röhr, Jin Ryoun Kim, Tana Siboonruang, Miguel A. Modestino, Hang Wang, André D. Taylor, Geunjin Kim
Publikováno v:
Nature. 594:51-56
In perovskite solar cells, doped organic semiconductors are often used as charge-extraction interlayers situated between the photoactive layer and the electrodes. The π-conjugated small molecule 2,2',7,7'-tetrakis[N,N-di(4-methoxyphenyl)amino]-9,9-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::037d12e821a0232008713fb9dbdbfb6a
https://doi.org/10.1038/s41586-021-03518-y
https://doi.org/10.1038/s41586-021-03518-y
Autor:
Edward Chau, Jin Ryoun Kim
Publikováno v:
Arch Biochem Biophys
Alzheimer’s disease (AD) and Parkinson’s disease (PD) are the two most common neurodegenerative disorders, characterized by aggregation of amyloid polypeptides, β-amyloid (Aβ) and α-synuclein (αS), respectively. Aβ and αS follow similar agg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd16a7ad3dd19af4278ed880e2c4bb45
https://doi.org/10.1016/j.abb.2022.109120
https://doi.org/10.1016/j.abb.2022.109120
Autor:
Jin Ryoun Kim, Edward Chau
Publikováno v:
Biochem Eng J
The aggregation of α-synuclein (αS) into oligomers and fibrils is implicated in the pathology of Parkinson’s Disease (PD). While a molecular probe for rapid and comprehensive evaluation of αS aggregation states is critical for a better understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9f90bf233829cb141a49005628a97d4
https://doi.org/10.1016/j.bej.2021.108292
https://doi.org/10.1016/j.bej.2021.108292
Autor:
Yan Xi Yang, Amy Wood, Edward Chau, Hyunjoo Kim, Jason Candreva, Jin Ryoun Kim, Vandan Shah, Tonianna Lynch, Timothy Charlton
Publikováno v:
ChemBioChem. 19:2566-2574
The aggregation of intrinsically disordered proteins into fibrils is implicated in many neurodegenerative diseases. Amyloid aggregation is a generic property of proteins as evidenced by globular proteins that often form amyloid aggregates under parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deaafb82b85ef20ddd3cde8052aafc86
https://doi.org/10.1002/cbic.201800472
https://doi.org/10.1002/cbic.201800472
Publikováno v:
Biochemistry
Aggregations of β-amyloid (Aβ) and α-synuclein (αS) into oligomeric and fibrillar assemblies are the pathological hallmarks of Alzheimer’s and Parkinson’s diseases, respectively. Although Aβ and αS affect different regions of the brain and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d4709af81a333cc8bac44c07b078b93
https://pubmed.ncbi.nlm.nih.gov/31854188
https://pubmed.ncbi.nlm.nih.gov/31854188
Autor:
Jaemin, Kong, Yongwoo, Shin, Jason A, Röhr, Hang, Wang, Juan, Meng, Yueshen, Wu, Adlai, Katzenberg, Geunjin, Kim, Dong Young, Kim, Tai-De, Li, Edward, Chau, Francisco, Antonio, Tana, Siboonruang, Sooncheol, Kwon, Kwanghee, Lee, Jin Ryoun, Kim, Miguel A, Modestino, Hailiang, Wang, André D, Taylor
Publikováno v:
Nature. 594(7861)
In perovskite solar cells, doped organic semiconductors are often used as charge-extraction interlayers situated between the photoactive layer and the electrodes. The π-conjugated small molecule 2,2',7,7'-tetrakis[N,N-di(4-methoxyphenyl)amino]-9,9-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f88c78628892d652624aaf624b61f0b9
https://pubmed.ncbi.nlm.nih.gov/34480150
https://pubmed.ncbi.nlm.nih.gov/34480150
Autor:
Eli Okon, Mary K. Cowman, Shulamit B. Wallach-Dayan, Jorge Alemany, David Naor, Darja Kanduc, Xiayun Huang, Lora Eshkar-Sebban, Keren Or Amar, Libat Bar Lev, Maayan Hemed-Shaked, Sharona Elgavish, Jordi Armengol, Michal Melamed, Shaul Beyth, Jin Ryoun Kim, Haim Ovadia, Eli Kedar, Shmuel Cohen, Edward Chau
Publikováno v:
Journal of Autoimmunity. 124:102713
Despite the existence of potent anti-inflammatory biological drugs e.g., anti-TNF and anti IL-6 receptor antibodies, for treating chronic inflammatory and autoimmune diseases, these are costly and not specific. Cheaper oral available drugs remain an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b948affc0ca59607cf79914d68861bd
https://doi.org/10.1016/j.jaut.2021.102713
https://doi.org/10.1016/j.jaut.2021.102713