Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jin Kawata"'
Autor:
Jin Kawata, Rui Yamaguchi, Takatoshi Yamamoto, Yasuji Ishimaru, Arisa Sakamoto, Manabu Aoki, Masafumi Kitano, Misako Umehashi, Eiji Hirose, Yasuo Yamaguchi
Publikováno v:
Cell Journal, Vol 17, Iss 4, Pp 692-700 (2016)
Objective: Neutrophils have an important role in the rapid innate immune response, and the release or active secretion of elastase from neutrophils is linked to various inflammatory responses. Purpose of this study was to determine how the human n
Externí odkaz:
https://doaj.org/article/0969ba683d434a83b653683c1638f8ff
Autor:
Manabu Aoki, Yasuo Yamaguchi, Tomomichi Ono, Katsurou Sagara, Yasuji Ishimaru, Jin Kawata, Eiji Hirose, Shinji Narahara, Tamami Matsmoto
Publikováno v:
Blood Cells, Molecules, and Diseases. 54:206-209
Background Monocytes and neutrophils are activated during disseminated intravascular coagulation. Tissue factor, the main initiator of coagulation, is expressed by monocytes, while elastase is released by neutrophils. Aims This study investigated tis
Publikováno v:
Biotechnology Letters. 36:241-250
Cells are generally stored at low temperature which slows their cellular metabolism. However, the stress induced by cold shock can lead to cell injury or death. Here, we found that exposing human leukemia HL-60 cells to cold shock followed by rewarmi
Publikováno v:
CellBio. :117-124
By visualizing DNA with diamidino phenylindole (DAPI), we found that hypothermal incubation followed by rewarming of human neutrophils resulted in an increased number of DAPI-positive objects representative of extensive DNA unfolding seemingly simila
Autor:
Shinji Narahara, Arisa Sakamoto, Rui Yamaguchi, Toshitaka Yamamoto, Hiroyuki Sugiuchi, Jin Kawata, Yasuo Yamaguchi, Tomomichi Ono, Eiji Hirose, Yasuji Ishimaru
Publikováno v:
Blood cells, moleculesdiseases. 55(2)
Neutrophil extracellular traps (NETs) have an important role in antimicrobial innate immunity and release substances that may modulate the immune response. We investigated the effects of soluble factors from NETs and neutrophil granule proteins on hu
Autor:
Daichi Inoue, Satoru Shinriki, Takeshi Kawamura, Akiko Nagamachi, Toshio Kitamura, Tatsuo Ichinohe, Toshiya Inaba, Akinori Kanai, Koji Iwato, Taiichi Kyo, Moe Kadono, Kumi Oshima, Akihiko Yokoyama, Jin Kawata, Hirotaka Matsui, Reina Nagase
Publikováno v:
Experimental Hematology. 44:745-754.e4
The DDX41 gene, encoding a DEAD-box type ATP-dependent RNA helicase, is rarely but reproducibly mutated in myeloid diseases. The acquired mutation in DDX41 is highly concentrated at c.G1574A (p.R525H) in the conserved motif VI located at the C-termin