Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Jin K. Cha"'
Autor:
Sara E. Kearney, Gergely Zahoránszky-Kőhalmi, Kyle R. Brimacombe, Mark J. Henderson, Caitlin Lynch, Tongan Zhao, Kanny K. Wan, Zina Itkin, Christopher Dillon, Min Shen, Dorian M. Cheff, Tobie D. Lee, Danielle Bougie, Ken Cheng, Nathan P. Coussens, Dorjbal Dorjsuren, Richard T. Eastman, Ruili Huang, Michael J. Iannotti, Surendra Karavadhi, Carleen Klumpp-Thomas, Jacob S. Roth, Srilatha Sakamuru, Wei Sun, Steven A. Titus, Adam Yasgar, Ya-Qin Zhang, Jinghua Zhao, Rodrigo B. Andrade, M. Kevin Brown, Noah Z. Burns, Jin K. Cha, Emily E. Mevers, Jon Clardy, Jason A. Clement, Peter A. Crooks, Gregory D. Cuny, Jake Ganor, Jesus Moreno, Lucas A. Morrill, Elias Picazo, Robert B. Susick, Neil K. Garg, Brian C. Goess, Robert B. Grossman, Chambers C. Hughes, Jeffrey N. Johnston, Madeleine M. Joullie, A. Douglas Kinghorn, David G.I. Kingston, Michael J. Krische, Ohyun Kwon, Thomas J. Maimone, Susruta Majumdar, Katherine N. Maloney, Enas Mohamed, Brian T. Murphy, Pavel Nagorny, David E. Olson, Larry E. Overman, Lauren E. Brown, John K. Snyder, John A. Porco, Fatima Rivas, Samir A. Ross, Richmond Sarpong, Indrajeet Sharma, Jared T. Shaw, Zhengren Xu, Ben Shen, Wei Shi, Corey R.J. Stephenson, Alyssa L. Verano, Derek S. Tan, Yi Tang, Richard E. Taylor, Regan J. Thomson, David A. Vosburg, Jimmy Wu, William M. Wuest, Armen Zakarian, Yufeng Zhang, Tianjing Ren, Zhong Zuo, James Inglese, Sam Michael, Anton Simeonov, Wei Zheng, Paul Shinn, Ajit Jadhav, Matthew B. Boxer, Matthew D. Hall, Menghang Xia, Rajarshi Guha, Jason M. Rohde
Publikováno v:
ACS Central Science, Vol 4, Iss 12, Pp 1727-1741 (2018)
Externí odkaz:
https://doaj.org/article/9f2975f36dd648f0b92b6e0f2b27c087
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 2, Pp 292-299 (2012)
Conversion of fatty acid hydroperoxides to epoxyalcohols is a well known secondary reaction of lipoxygenases, described for S-specific lipoxygenases forming epoxyalcohols with a trans-epoxide configuration. Here we report on R-specific lipoxygenase s
Externí odkaz:
https://doaj.org/article/35f83385e9e74d5281d9b786d876f67e
Autor:
Rajarshi Guha, Anton Simeonov, Jesus Moreno, Min Shen, Yi Tang, James Inglese, Jared T. Shaw, Jimmy Ming-Tai Wu, Samir A. Ross, Tobie D. Lee, Surendra Karavadhi, Dorian M. Cheff, Susruta Majumdar, Adam Yasgar, Richard E. Taylor, Sam Michael, Zhengren Xu, Wei Sun, Lucas A. Morrill, David A. Vosburg, Wei Zheng, Corey R. J. Stephenson, Noah Z. Burns, Michael J. Iannotti, Carleen Klumpp-Thomas, Richard T. Eastman, Ohyun Kwon, Armen Zakarian, Yufeng Zhang, Matthew D. Hall, Sara E. Kearney, Ya Qin Zhang, Tongan Zhao, Ken Cheng, Indrajeet Sharma, Nathan P. Coussens, Ruili Huang, Derek S. Tan, Paul Shinn, Michael J. Krische, Caitlin Lynch, Jon Clardy, Larry E. Overman, Kanny K. Wan, Chambers C. Hughes, Madeleine M. Joullié, Thomas J. Maimone, Matthew B. Boxer, Jason A. Clement, A. Douglas Kinghorn, Peter A. Crooks, Brian C. Goess, Robert B. Susick, Gergely Zahoránszky-Kőhalmi, Alyssa L. Verano, Danielle Bougie, Jacob S. Roth, Ben Shen, Dorjbal Dorjsuren, Elias Picazo, Jinghua Zhao, John K. Snyder, Rodrigo B. Andrade, Wei Shi, Jin K. Cha, Brian T. Murphy, Fatima Rivas, William M. Wuest, Jake Ganor, Robert B. Grossman, Pavel Nagorny, Emily Mevers, Enas I. Mohamed, David E. Olson, John A. Porco, Neil K. Garg, Srilatha Sakamuru, Jason M. Rohde, M. Kevin Brown, Menghang Xia, Tianjing Ren, Steve Titus, Christopher Dillon, Mark J. Henderson, Zhong Zuo, Regan J. Thomson, David G. I. Kingston, Lauren E. Brown, Jeffrey N. Johnston, Katherine N. Maloney, Richmond Sarpong, Zina Itkin, Gregory D. Cuny, Ajit Jadhav, Kyle R. Brimacombe
Publikováno v:
ACS Central Science
ACS Central Science, Vol 4, Iss 12, Pp 1727-1741 (2018)
ACS Central Science, Vol 4, Iss 12, Pp 1727-1741 (2018)
Natural products and their derivatives continue to be wellsprings of nascent therapeutic potential. However, many laboratories have limited resources for biological evaluation, leaving their previously isolated or synthesized compounds largely or com
Publikováno v:
Organic & Biomolecular Chemistry. 14:3544-3557
The cyclopentane core is ubiquitous among a large number of biologically relevant natural products. Cyclopentenones have been shown to be versatile intermediates for the stereoselective preparation of highly substituted cyclopentane derivatives. Alle
Autor:
William E. Boeglin, Donald F. Stec, Jin K. Cha, Claus Schneider, Markus Voehler, Alan R. Brash
Publikováno v:
Journal of Biological Chemistry. 288:20797-20806
Specialized cytochromes P450 or catalase-related hemoproteins transform fatty acid hydroperoxides to allene oxides, highly reactive epoxides leading to cyclopentenones and other products. The stereochemistry of the natural allene oxides is incomplete
Autor:
Yuki Hirokami, Naoki Asano, J. L. Kiappes, Nicole Zitzmann, Isao Adachi, George W. J. Fleet, Shota Miyawaki, Russell J. Molyneux, Kyoko Kinami, Atsushi Kato, Robert J. Nash, Jackie Hollinshead, Yutaro Tsuji, Jin K. Cha
Publikováno v:
Phytochemistry. 111
© 2014 Elsevier Ltd. All rights reserved. We report the isolation and structural determination of fourteen iminosugars, containing five pyrrolizidines and five indolizidines, from Castanospermum australe. The structure of a new alkaloid was elucidat
Publikováno v:
Biochemistry. 43:10730-10738
Genetically engineered strains of Escherichia coli and Pseudomonas aeruginosa were prepared harboring the gene cluster nirFDLGH from Pseudomonas stutzeri substrain ZoBell on a high copy plasmid. These genes have been previously implicated as being es
Publikováno v:
Analytical Biochemistry. 284:125-135
Stereospecifically 3H-labeled substrates are useful tools in studying the mechanism of hydrogen abstractions involved in the oxygenation of polyunsaturated fatty acids. Here, we describe modified methods for the synthesis of arachidonic acids labeled
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 2, Pp 292-299 (2012)
Conversion of fatty acid hydroperoxides to epoxyalcohols is a well known secondary reaction of lipoxygenases, described for S-specific lipoxygenases forming epoxyalcohols with a trans-epoxide configuration. Here we report on R-specific lipoxygenase s
Autor:
Jin K. Cha, B. Andes Hess
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 281:11-14
An ab initio study of the structure and vibrational spectrum of allene oxide and three of its isotopomers has been carried out (MP2/6-31G∗). A comparison of the computed spectra with the experimental spectra reported previously (K.A. Singmaster and