Zobrazeno 1 - 10
of 1 537
pro vyhledávání: '"Jin J, Zhou"'
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 9 (2024)
Background Heart failure (HF) is a serious condition with increasing prevalence, high morbidity, and increased mortality. Obesity is an established risk factor for HF. Fluctuation in body mass index (BMI) has shown a higher risk of cardiovascular out
Externí odkaz:
https://doaj.org/article/5c09babe44a3444fb266dfa45154de62
Autor:
Derek Lee, Zachary Spencer Dunn, Wenbin Guo, Carl J. Rosenthal, Natalie E. Penn, Yanqi Yu, Kuangyi Zhou, Zhe Li, Feiyang Ma, Miao Li, Tsun-Ching Song, Xinjian Cen, Yan-Ruide Li, Jin J. Zhou, Matteo Pellegrini, Pin Wang, Lili Yang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Allogeneic Vγ9Vδ2 (Vδ2) T cells have emerged as attractive candidates for developing cancer therapy due to their established safety in allogeneic contexts and inherent tumor-fighting capabilities. Nonetheless, the limited clinical success
Externí odkaz:
https://doaj.org/article/db1b9f3012ed4c62863e57ef35407db7
Autor:
Yan-Ruide Li, Christopher J. Ochoa, Yichen Zhu, Adam Kramer, Matthew Wilson, Ying Fang, Yuning Chen, Tanya Singh, Gabriella Di Bernardo, Enbo Zhu, Derek Lee, Neda A. Moatamed, Joanne Bando, Jin J. Zhou, Sanaz Memarzadeh, Lili Yang
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107952- (2023)
Summary: Ovarian cancer (OC) is highly lethal due to late detection and frequent recurrence. Initial treatments, comprising surgery and chemotherapy, lead to disease remission but are invariably associated with subsequent relapse. The identification
Externí odkaz:
https://doaj.org/article/e68f8f2be25746a2bb19bb49db0b3901
Autor:
Rohan Khera, Jing Li, Katherine Simon, Yuan Lu, Joseph S Ross, Talita Duarte-Salles, Michael E Matheny, Harlan Krumholz, Kenneth KC Man, Carlen Reyes, Paul Nagy, Nigam Shah, Martijn J Schuemie, Daniel R Morales, Scott L DuVall, Seng Chan You, Jose D Posada, George Hripcsak, Marc A Suchard, Patrick B Ryan, Anna Ostropolets, Michael Cook, Evan Minty, Andrea Pistillo, Clair Blacketer, Arya Aminorroaya, Thomas Falconer, Nestoras Mathioudakis, Jin J Zhou, Can Yin, Kelly Li, Lovedeep Singh Dhingra, Faaizah Arshad, Mary G Bowring, Fan Bu, David A Dorr, Tina E French, Elizabeth E Hanchrow, Scott Horban, Wallis CY Lau, Yuntian Liu, Michael F McLemore, Akihiko Nishimura, Nicole Pratt, Sarah Seager, Eric YF Wan, Jianxiao Yang
Publikováno v:
BMJ Medicine, Vol 2, Iss 1 (2023)
Objective To assess the uptake of second line antihyperglycaemic drugs among patients with type 2 diabetes mellitus who are receiving metformin.Design Federated pharmacoepidemiological evaluation in LEGEND-T2DM.Setting 10 US and seven non-US electron
Externí odkaz:
https://doaj.org/article/cd277362d5684feaa32b34690f64437c
Publikováno v:
Cardiovascular Diabetology, Vol 20, Iss 1, Pp 1-9 (2021)
Abstract Aims Low C-peptide levels, indicating beta-cell dysfunction, are associated with increased within-day glucose variation and hypoglycemia. In advanced type 2 diabetes, severe hypoglycemia and increased glucose variation predict cardiovascular
Externí odkaz:
https://doaj.org/article/657936416ccc43ddb121d182fc58db61
Autor:
Yann Klimentidis, Zhao Chen, Leslie V Farland, Xin Tang, Roberta Diaz Brinton, Raymond Migrino, Peter Reaven, Kathleen Rodgers, Jin J Zhou
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 10, Iss 5 (2022)
Introduction Studies have reported that antidiabetic medications (ADMs) were associated with lower risk of dementia, but current findings are inconsistent. This study compared the risk of dementia onset in patients with type 2 diabetes (T2D) treated
Externí odkaz:
https://doaj.org/article/87abd29d73a34e9b8e9ff7f328a2fe32
Autor:
Wanjun Gu, Junchao Shi, Hui Liu, Xudong Zhang, Jin J. Zhou, Musheng Li, Dandan Zhou, Rui Li, Jingzhu Lv, Guoxia Wen, Shanshan Zhu, Ting Qi, Wei Li, Xiaojing Wang, Zhaohua Wang, Hua Zhu, Changcheng Zhou, Kenneth S. Knox, Ting Wang, Qi Chen, Zhongqing Qian, Tong Zhou
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-6 (2020)
Abstract One unmet challenge in lung cancer diagnosis is to accurately differentiate lung cancer from other lung diseases with similar clinical symptoms and radiological features, such as pulmonary tuberculosis (TB). To identify reliable biomarkers f
Externí odkaz:
https://doaj.org/article/969c6ca6dbc243e2b30e9967e2490e3f
Autor:
Gina M. Peloso, Catherine Tcheandjieu, John E. McGeary, Daniel C. Posner, Yuk-Lam Ho, Jin J. Zhou, Austin T. Hilliard, Jacob Joseph, Christopher J. O’Donnell, Jimmy T. Efird, Dana C. Crawford, Wen-Chih Wu, Mehrdad Arjomandi, VA Million Veteran Program COVID-19 Science Initiative, Yan V. Sun, Themistocles L Assimes, Jennifer E. Huffman
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
SARS-CoV-2 has caused symptomatic COVID-19 and widespread death across the globe. We sought to determine genetic variants contributing to COVID-19 susceptibility and hospitalization in a large biobank linked to a national United States health system.
Externí odkaz:
https://doaj.org/article/f7465494544b4fb2a60f3a239083ee54
Autor:
Peter D. Reaven, Michelle Newell, Salvador Rivas, Xinkai Zhou, Gregory J. Norman, Jin J. Zhou
Publikováno v:
Diabetes Care. 46:854-863
OBJECTIVETo determine the benefit of starting continuous glucose monitoring (CGM) in adult-onset type 1 diabetes (T1D) and type 2 diabetes (T2D) with regard to longer-term glucose control and serious clinical events.RESEARCH DESIGN AND METHODSA retro
Autor:
Wonji, Kim, Julian, Hecker, R Graham, Barr, Eric, Boerwinkle, Brian, Cade, Adolfo, Correa, Josée, Dupuis, Sina A, Gharib, Leslie, Lange, Stephanie J, London, Alanna C, Morrison, George T, O'Connor, Elizabeth C, Oelsner, Bruce M, Psaty, Ramachandran S, Vasan, Susan, Redline, Stephen S, Rich, Jerome I, Rotter, Bing, Yu, Christoph, Lange, Ani, Manichaikul, Jin J, Zhou, Tamar, Sofer, Edwin K, Silverman, Dandi, Qiao, Michael H, Cho
Publikováno v:
Hum Mol Genet
Rationale: Genetic variation has a substantial contribution to chronic obstructive pulmonary disease (COPD) and lung function measurements. Heritability estimates using genome-wide genotyping data can be biased if analyses do not appropriately accoun