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Supplementary Figure 1 from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

PDF file - 376K, Inhibition rates (IR) of tumor growth (A) and response rates at IR30 (chemosensitivity) (B). The IRs and IR30 of a single bevacizumab or cetuximab regimen were significantly less than those of the other four combination regimens (P �

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a473ba7dea4671299522a34854e2ed29
https://doi.org/10.1158/1078-0432.22444835

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Data from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

Purpose: Methods for predicting individual responsiveness to targeted chemotherapy are urgently needed, considering the frequent resistance and extremely high cost.Experimental Design: A chemosensitive single-nucleotide polymorphism (SNP) discovery s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a587e29c208d9c2c2dddc813d4808d
https://doi.org/10.1158/1078-0432.c.6520304.v1

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Supplementary Figure 2 from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

PDF file - 2.6MB, Genome-wide association with in vitro chemosensitivity to targeted regimens: FRB (A), FXB (B), FRC (C), and FXC (D). Association of SNPs with the inhibition ratio was tested by linear regression analysis. P-values of < 0.001 are ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cafa4041221aa1402e52d723d9e475
https://doi.org/10.1158/1078-0432.22444832

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Supplementary Figure 3 from Novel Chemosensitive Single-Nucleotide Polymorphism Markers to Targeted Regimens in Metastatic Colorectal Cancer

Autor: Yong S. Kim, Hyoungseok Ju, Tae W. Kim, Seon A. Roh, Chan W. Kim, Eun Y. Choi, Ye J. Ha, Dong H. Cho, Seon Y. Kim, Jin C. Kim

PDF file - 1.4MB, Cell viability measured by MTT assay in transfected CRC clones (a. DFNB31 rs2274159; b. ANXA11 rs1049550; c. LINS1 rs11247226) treated with FRC (a), FRB (b), and FXB (c), respectively. Bold font, P < 0.05. FRC, FOLFIRI + cetuximab;

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd00e457c27686519a684a341d57439
https://doi.org/10.1158/1078-0432.22444829.v1

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Tumor immune microenvironment of primary colorectal adenocarcinomas metastasizing to the liver or lungs

Autor: Ka Hee Tak, In J. Park, Yong S. Yoon, Dong-Hyung Cho, Chan W. Kim, Yong Sung Kim, Seon-Young Kim, Seong H Park, Jong L Lee, Ye J. Ha, Seon-Kyu Kim, Jin C. Kim

Publikováno v: Journal of Surgical Oncology. 124:1136-1145

Background Because of the heterogeneity of metastatic colorectal cancer (mCRC), a genome-wide analysis was performed to characterize the tumor immune microenvironment (TIME). Methods RNA-seq analysis of 62 primary CRCs without and 63 with systemic me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d720b423a203dacb31a35b467526e2
https://doi.org/10.1002/jso.26631

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Akademický článek

Analysis of Surgical Treatments for Circumferentially Protruding Haemorrhoids: Complete Excision with Repair Using Flaps Versus Primary Excision with Secondary Suture-ligation

Autor: Jin C. Kim

Publikováno v: Asian Journal of Surgery, Vol 29, Iss 3, Pp 128-134 (2006)

Circumferentially protruding haemorrhoids (CPH) are troublesome lesions for both patients and surgeons, and in most cases demand surgical intervention. However, such surgery carries the risks of complications and recurrence. This study compared two s

Externí odkaz: https://doaj.org/article/fef12127d0fa411c806a8bc6d499ebdf

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Utility of indocyanine-green fluorescent imaging during robot-assisted sphincter-saving surgery on rectal cancer patients

Autor: Abdulrahman Muaod Alotaibi, Jong L. Lee, Jin C. Kim, Yong S. Yoon, Jihun Kim

Publikováno v: The International Journal of Medical Robotics and Computer Assisted Surgery. 12:710-717

Background There have been few studies describing the use of indocyanine green (ICG) fluorescent imaging during robot-assisted (RA) sphincter-saving operations (SSOs) and assessing its potential role in reducing anastomotic leak (AL). Methods A conse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::07717318a763b1fee5ad653653563311
https://doi.org/10.1002/rcs.1710

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A comparison of the technical and oncologic validity between robot-assisted and conventional open abdominoperineal resection

Autor: Jin C. Kim, In J. Park, Yong S. Yoon, Jae Y. Kwak, Chan W. Kim

Publikováno v: International Journal of Colorectal Disease. 29:961-969

This study was to ascertain whether a robot-assisted (RA) approach to APR might facilitate a cylindrical APR by enabling a deeper pelvic dissection during an abdominal approach, concurrently comparing the feasibility and short-term oncologic outcomes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c8229a16a29536533b91abbbdd8b2b
https://doi.org/10.1007/s00384-014-1916-9

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Completely abdominal intersphincteric resection for lower rectal cancer: feasibility and comparison of robot-assisted and open surgery

Autor: Yong S. Yoon, Chan W. Kim, Jin C. Kim, Seok-B. Lim, In J. Park, Chang N. Kim

Publikováno v: Surgical Endoscopy. 28:2734-2744

Most previous studies of intersphincteric resection (ISR) adopted a two-stage procedure involving abdominal and transanal approaches. We performed completely abdominal ISR via open and a robot-assisted (RA) approaches as treatments for lower rectal c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2e18f60fbcc678c7fb3a506763314b
https://doi.org/10.1007/s00464-014-3509-7

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