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Akademický článek

Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks

Autor: Jae-Seung Yun, Sang-Hyuk Jung, Su-Nam Lee, Seung Min Jung, Penn Medicine Biobank, Hong-Hee Won, Dokyoon Kim, Jin A. Choi

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)

Abstract Background Glaucoma is a leading cause of worldwide irreversible blindness. Considerable uncertainty remains regarding the association between a variety of phenotypes and the genetic risk of glaucoma, as well as the impact they exert on the

Externí odkaz: https://doaj.org/article/ee9f787f0fe84ae5b7c41e8bffa39835

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Akademický článek

Predicting the development of normal tension glaucoma and related risk factors in normal tension glaucoma suspects

Autor: Hae-Young Lopilly Park, Da Young Shin, Soo Ji Jeon, Yong-Chan Kim, Younhea Jung, Eun Kyoung Kim, Hye-Young Shin, Kyoung In Jung, Jin A. Choi, Na Young Lee, Seung Woo Hong, Chan Kee Park

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)

Abstract This study investigated the predicted risk factors for the development of normal-tension glaucoma (NTG) in NTG suspects. A total of 684 eyes of 379 NTG suspects who were followed-up for at least 5 years were included in the study. NTG suspec

Externí odkaz: https://doaj.org/article/e8434c08287c47ce9b9cbf1e4c54a08f

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Akademický článek

Role of MCP-1 and IL-8 in viral anterior uveitis, and contractility and fibrogenic activity of trabecular meshwork cells

Autor: Jiyoung Lee, Jin A. Choi, Hyun-hee Ju, Ju-Eun Kim, Soon-Young Paik, Ponugoti Vasantha Rao

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)

Abstract The inflammatory chemokines, monocyte chemoattractant protein (MCP)-1 and IL-8, are produced by normal trabecular meshwork cells (TM) and elevated in the aqueous humor of primary open angle glaucoma (POAG) and hypertensive anterior uveitis a

Externí odkaz: https://doaj.org/article/85a67f1efcf14fa897fb3cd076c7c3df

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Akademický článek

The Enhanced Inhibitory Effect of Estrogen on PD-L1 Expression Following Nrf2 Deficiency in the AOM/DSS Model of Colitis-Associated Cancer

Autor: Changhee Kang, Chin-Hee Song, Nayoung Kim, Ryoung Hee Nam, Soo In Choi, Jeong Eun Yu, Heewon Nho, Jin A. Choi, Jin Won Kim, Hee Young Na, Ha-Na Lee, Young-Joon Surh

Publikováno v: Frontiers in Oncology, Vol 11 (2021)

Nuclear factor erythroid 2-related factor 2 (Nrf2) plays a dual role in carcinogenesis. We previously reported that Nrf2 deficiency enhances the anti-tumorigenic effect of 17β-estradiol (E2) in an azoxymethane (AOM)/dextran sodium sulfate (DSS) mode

Externí odkaz: https://doaj.org/article/8e9848fc1ad44b7da4ed93e25b105aaa

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Akademický článek

Prognostic efficacy of lymph node parameters in resected ampullary adenocarcinoma based on long-term follow-up data after adjuvant treatment

Autor: Namyoung Park, In Rae Cho, Sang Hyub Lee, Joo Seong Kim, Jin Ho Choi, Min Woo Lee, Woo Hyun Paik, Kwang Ro Joo, Ji Kon Ryu, Yong-Tae Kim

Publikováno v: World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-13 (2024)

Abstract Background Lymph node (LN) metastasis is an important prognostic factor in the ampulla of Vater (AoV) adenocarcinoma. Various LN parameters have been proposed, but their prognostic efficacy has not been compared in the same population. We ai

Externí odkaz: https://doaj.org/article/28dbb22f7ada48bcb8e41eddb0328889

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Akademický článek

Sex Difference in 5-year Relative Survival Following Percutaneous Coronary Intervention

Autor: Jin-Ho Choi, Jung-Min Choi, Ki-Hong Choi, Joo Myung Lee, Taek Kyu Park, Jeong Hoon Yang, Young Bin Song, Joo-Yong Hahn, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Eun-Seok Shin

Publikováno v: European Cardiology Review, Vol 19, Iss , Pp - (2024)

Background: Survival rates following percutaneous coronary intervention (PCI) show variability across studies, particularly regarding sex-specific outcomes. Relative survival analysis, which considers survival patterns in sex- and age-matched general

Externí odkaz: https://doaj.org/article/a4c197878a59494b816243857c033811

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Akademický článek

Ganglion Cell-Inner Plexiform Layer, Peripapillary Retinal Nerve Fiber Layer, and Macular Thickness in Eyes with Myopic β-Zone Parapapillary Atrophy

Autor: Jin-woo Kwon, Jin A. Choi, Jung-sub Kim, Tae Yoon La

Publikováno v: Journal of Ophthalmology, Vol 2016 (2016)

Purpose. To assess the correlations of myopic β-zone parapapillary atrophy (β-PPA) with the optic nerve head (ONH) and retina. Methods. We selected 27 myopic patients who showed prominent β-PPA in one eye and no β-PPA in the other eye. We studied

Externí odkaz: https://doaj.org/article/2d6c0a379a8045dc8fe062269131b7ee

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