Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Jin‑Shui Zhu"'
Publikováno v:
Advanced Science, Vol 11, Iss 30, Pp n/a-n/a (2024)
Abstract Helicobacter pylori (H. pylori) infection is the primary risk factor for the pathogenesis of gastric cancer (GC). N6‐methyladenosine (m6A) plays pivotal roles in mRNA metabolism and hnRNPA2B1 as an m6A reader is shown to exert m6A‐depend
Externí odkaz:
https://doaj.org/article/85559fc5142348a8920c6db8b5af7ebb
Publikováno v:
Pharmacological Research, Vol 204, Iss , Pp 107206- (2024)
Chemoresistance is a major therapeutic challenge in advanced gastric cancer (GC). N6-methyladenosine (m6A) RNA modification has been shown to play fundamental roles in cancer progression. However, the underlying mechanisms by which m6A modification o
Externí odkaz:
https://doaj.org/article/926fa9af60184996b8e5f2609881d5da
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-14 (2022)
Abstract Background N6-methyladenosine (m6A) RNA methylation and circular RNAs (circRNAs) have been shown to act vital roles in multiple malignancies including gastric cancer (GC). However, there is little knowledge about how m6A modification of circ
Externí odkaz:
https://doaj.org/article/eb258e8c9f1140af87bb160cd1985bf9
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract N6-methyladenosine (m6A) is one of the most common RNA modifications in eukaryotes, mainly in messenger RNA (mRNA). Increasing evidence shows that m6A methylation modification acts an essential role in various physiological and pathological
Externí odkaz:
https://doaj.org/article/2355992c4b564caa8c6068cdb88c057c
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Dihydroartemisinin (DHA), a well-known antimalarial drug, has been widely investigated for its antitumor effects in multiple malignancies. However, its effects and regulatory mechanisms in colorectal cancer (CRC) are still unproved. In this study, in
Externí odkaz:
https://doaj.org/article/af667f9e73014cd7b4f3b09a5b11b918
Autor:
Xiao-Yu Chen, Wei Da, Rui Liang, Hui-Ning Fan, You-Cai Yi, Ming Chen, Huang-Wen Qin, Jing Zhang, Jin-Shui Zhu
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Objective: To explore the detective value of magnetically controlled robotic capsule endoscopy (MCRCE) in patients with suspected small intestinal disease.Patients and Methods: In total, 1,802 patients with suspected small intestinal disease and nega
Externí odkaz:
https://doaj.org/article/6179301f4f10480db094e1e768c53d31
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract N6-methyladenosine (m6A) is identified as the most common, abundant and conserved internal transcriptional modification, especially within eukaryotic messenger RNAs (mRNAs). M6A modification is installed by the m6A methyltransferases (METTL3
Externí odkaz:
https://doaj.org/article/c65004f7f185459bb8afbd9d4468a6c0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
ObjectivesN6-methyladenosine (m6A) RNA methylation is implicated in the progression of multiple cancers via influencing mRNA modification. YTHDF1 can act as an oncogene in gastric cancer (GC), while the biological mechanisms via which YTHDF1 regulate
Externí odkaz:
https://doaj.org/article/716405fad4eb4903abfc71d3e5924802
Autor:
Xiao-Yu Chen, Hui-Ning Fan, Huang-Kai Zhang, Huang-Wen Qin, Li Shen, Xiang-Tian Yu, Jing Zhang, Jin-Shui Zhu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
The development of non-invasive, inexpensive, and effective early diagnosis tests for gastric and small-bowel lesions is an urgent requirement. The introduction of magnetically guided capsule endoscopy (MGCE) has aided examination of the small bowel
Externí odkaz:
https://doaj.org/article/c4851c9230a8431491112a545c14f3c8
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 11 (2018)
Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of hepatic pathology, ranging from simple accumulation of fat in its most benign form, steatohepatitis, to cirrhosis in its most advanced form. The prevalence of NAFLD is 20–30% in adul
Externí odkaz:
https://doaj.org/article/f544a69155d048a9a3721a9dda1affd2