Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Jin‐Xuan Fan"'
Autor:
Meng Guan, Kai Cheng, Xiao-Ting Xie, Yong Li, Meng-Wen Ma, Bin Zhang, Si Chen, Wei Chen, Bo Liu, Jin-Xuan Fan, Yuan-Di Zhao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cuproptosis is an emerging mode of programmed cell death for tumor suppression but sometimes gets resisted by tumor cells resist under specific mechanisms. Inhibiting copper transporter ATPase (ATP7A) was found to disrupt copper ion homeosta
Externí odkaz:
https://doaj.org/article/1f201d2373334c37a30cd8c111d38a58
Autor:
Fang Zhang, Kai Cheng, Xiao-Shuai Zhang, Sui Zhou, Jia-Hua Zou, Ming-Yu Tian, Xiao-Lin Hou, Yong-Guo Hu, Jing Yuan, Jin-Xuan Fan, Yuan-Di Zhao, Tian-Cai Liu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract The abnormal structure of tumor vascular seriously hinders the delivery and deep penetration of drug in tumor therapy. Herein, an integrated and tumor microenvironment (TME)-responsive nanocarrier is designed, which can dilate vessle and imp
Externí odkaz:
https://doaj.org/article/390ae7c357c94c7d819c4c19fbf1fe74
Autor:
Xiao‐Lin Hou, Bin Zhang, Kai Cheng, Fang Zhang, Xiao‐Ting Xie, Wei Chen, Lin‐Fang Tan, Jin‐Xuan Fan, Bo Liu, Qiu‐Ran Xu
Publikováno v:
Advanced Science, Vol 11, Iss 24, Pp n/a-n/a (2024)
Abstract Customizable and number‐tunable enzyme delivery nanocarriers will be useful in tumor therapy. Herein, a phage vehicle, T4‐Lox‐DNA‐Fe (TLDF), which adeptly modulates enzyme numbers using phage display technology to remodel the tumor m
Externí odkaz:
https://doaj.org/article/2e82387bc57545799e31b1ecaa0bbb2e
Autor:
Di-Wei Zheng, Fan Gao, Qian Cheng, Peng Bao, Xue Dong, Jin-Xuan Fan, Wen Song, Xuan Zeng, Si-Xue Cheng, Xian-Zheng Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Immune checkpoint blockade (ICB) immunotherapy efficacy has still limitations. Here, the authors generate a vaccine that integrates CD274 siRNA into the L1 protein of human papillomavirus, which cooperates with ICB by activating innate immunity in br
Externí odkaz:
https://doaj.org/article/a6b06cb0091e4b669efd503940dbedac
Publikováno v:
Advanced Science, Vol 6, Iss 24, Pp n/a-n/a (2019)
Abstract Multitudinous industrial products in daily life put human health at risk of heavy metal exposure, and natural bacteria have displayed superior performance in bioadsorption and biodegradation of heavy metal. In this study, a bacteria‐based
Externí odkaz:
https://doaj.org/article/1b2a6dec66854c0f9657f840958d969c
Autor:
Di-Wei Zheng, Ying Chen, Zi-Hao Li, Lu Xu, Chu-Xin Li, Bin Li, Jin-Xuan Fan, Si-Xue Cheng, Xian-Zheng Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Targeting tumors with bacteria as vehicles for metabolite therapy suffers from low efficiency and robustness. Here, the authors combine carbon nitride with nitric oxide generation enzyme-positive E. coli for photo-controlled metabolite therapy (PMT)
Externí odkaz:
https://doaj.org/article/d16bc80f86904250a7bda65fe7249261
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 8, p3193-3212, 20p
Publikováno v:
Journal of Controlled Release. 356:59-71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::845339fe56ad1900184c289aa53d7560
https://doi.org/10.1016/j.jconrel.2023.02.028
https://doi.org/10.1016/j.jconrel.2023.02.028
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 18(49)
Although anticancer vaccines have achieved certain effects in early clinical practice, T cell immunity as the most common responsive pattern of anticancer vaccines is still limited by unsatisfied tumor recognition and inhibition efficiency. As the cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9dd5a43b93952392276190f141177f
https://pubmed.ncbi.nlm.nih.gov/36285774
https://pubmed.ncbi.nlm.nih.gov/36285774
Publikováno v:
Nano Letters. 21:4270-4279
Engineered bacteria are promising bioagents to synthesize antitumor drugs at tumor sites with the advantages of avoiding drug leakage and degradation during delivery. Here, we report an optically controlled material-assisted microbial system by biosy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4da7d75bd351dd2c27def0fb6b8da00c
https://doi.org/10.1021/acs.nanolett.1c00408
https://doi.org/10.1021/acs.nanolett.1c00408