Zobrazeno 1 - 10
of 662
pro vyhledávání: '"Jin‐Moo Lee"'
Autor:
Xiaodan Wang, Jonah A. Padawer-Curry, Annie R. Bice, Byungchan Kim, Zachary P. Rosenthal, Jin-Moo Lee, Manu S. Goyal, Shannon L. Macauley, Adam Q. Bauer
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114723- (2024)
Summary: Neurovascular coupling (NVC) and neurometabolic coupling (NMC) provide the basis for functional magnetic resonance imaging and positron emission tomography to map brain neurophysiology. While increases in neuronal activity are often accompan
Externí odkaz:
https://doaj.org/article/1867e3f425cf438499800afa11f88772
Autor:
Jeremy F. Strain, Maryam Rahmani, Donna Dierker, Christopher Owen, Hussain Jafri, Andrei G. Vlassenko, Kyle Womack, Jurgen Fripp, Duygu Tosun, Tammie L.S. Benzinger, Michael Weiner, Colin Masters, Jin-Moo Lee, John C. Morris, Manu S. Goyal
Publikováno v:
NeuroImage, Vol 285, Iss , Pp 120494- (2024)
White matter hyperintensities (WMH) are nearly ubiquitous in the aging brain, and their topography and overall burden are associated with cognitive decline. Given their numerosity, accurate methods to automatically segment WMH are needed. Recent deve
Externí odkaz:
https://doaj.org/article/9a77e55dc1474884adecbe5906150bfa
Autor:
Samuel Chidiebere Uzoechi, Boyce Edwin Collins, Cody Joseph Badeaux, Yan Li, Sang Su Kwak, Doo Yeon Kim, Daniel Todd Laskowitz, Jin-Moo Lee, Yeoheung Yun
Publikováno v:
Applied Sciences, Vol 14, Iss 9, p 3917 (2024)
The disruption of the blood–brain barrier (BBB) in Alzheimer’s Disease (AD) is largely influenced by amyloid beta (Aβ). In this study, we developed a high-throughput microfluidic BBB model devoid of a physical membrane, featuring endothelial cel
Externí odkaz:
https://doaj.org/article/d1b2cd7bf5b54d5199c18eb36023c117
Neuroinflammation and amyloid deposition in the progression of mixed Alzheimer and vascular dementia
Autor:
Chunwei Ying, Peter Kang, Michael M. Binkley, Andria L. Ford, Yasheng Chen, Jason Hassenstab, Qing Wang, Jeremy Strain, John C. Morris, Jin-Moo Lee, Tammie L.S. Benzinger, Hongyu An
Publikováno v:
NeuroImage: Clinical, Vol 38, Iss , Pp 103373- (2023)
Background: Alzheimer’s disease (AD) and vascular contributions to cognitive impairment and dementia (VCID) pathologies coexist in patients with cognitive impairment. Abnormal amyloid beta (Aβ) deposition is the hallmark pathologic biomarker for A
Externí odkaz:
https://doaj.org/article/cb7e453f9b5347cca52217a73e2e03f2
Autor:
Asher J. Albertson, Eric C. Landsness, Michelle J. Tang, Ping Yan, Hanyang Miao, Zachary P. Rosenthal, Byungchan Kim, Joseph C. Culver, Adam Q Bauer, Jin-Moo Lee
Publikováno v:
NeuroImage, Vol 257, Iss , Pp 119287- (2022)
Normal aging is associated with a variety of neurologic changes including declines in cognition, memory, and motor activity. These declines correlate with neuronal changes in synaptic structure and function. Degradation of brain network activity and
Externí odkaz:
https://doaj.org/article/43427e91ea0d47f494db7db05b57a97d
Autor:
Jara Cárcel-Márquez, Elena Muiño, Cristina Gallego-Fabrega, Natalia Cullell, Miquel Lledós, Laia Llucià-Carol, Tomás Sobrino, Francisco Campos, José Castillo, Marimar Freijo, Juan Francisco Arenillas, Victor Obach, José Álvarez-Sabín, Carlos A. Molina, Marc Ribó, Jordi Jiménez-Conde, Jaume Roquer, Lucia Muñoz-Narbona, Elena Lopez-Cancio, Mònica Millán, Rosa Diaz-Navarro, Cristòfol Vives-Bauza, Gemma Serrano-Heras, Tomás Segura, Laura Ibañez, Laura Heitsch, Pilar Delgado, Rajat Dhar, Jerzy Krupinski, Raquel Delgado-Mederos, Luis Prats-Sánchez, Pol Camps-Renom, Natalia Blay, Lauro Sumoy, Rafael de Cid, Joan Montaner, Carlos Cruchaga, Jin-Moo Lee, Joan Martí-Fàbregas, Israel Férnandez-Cadenas
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundOccult atrial fibrillation (AF) is one of the major causes of embolic stroke of undetermined source (ESUS). Knowing the underlying etiology of an ESUS will reduce stroke recurrence and/or unnecessary use of anticoagulants. Understanding car
Externí odkaz:
https://doaj.org/article/59cc2ac670ff4756af4144e6cde2a58a
Autor:
Hye Won Lee, Lin Ang, Myeong Soo Lee, Kyoung Sun Park, Jin-Moo Lee, Chang-Hoon Lee, Dong Chul Kim, Jeong-Eun Yoo, Seung-Jeong Yang, Tae-Young Choi
Publikováno v:
Clinical and Experimental Obstetrics & Gynecology, Vol 48, Iss 3, Pp 649-653 (2021)
Background: Few studies investigated the prescription patterns of traditional Korean medicine (TKM) therapies for PCOS in clinical practice. The purpose of this study was to identify the common symptoms, herbal prescription patterns and types of adju
Externí odkaz:
https://doaj.org/article/4d2b589a598449d1b8b1ace0d31e16c6
Autor:
Atul Kumar, Yasheng Chen, Aaron Corbin, Ali Hamzehloo, Amin Abedini, Zeynep Vardar, Grace Carey, Kunal Bhatia, Laura Heitsch, Jamal J. Derakhshan, Jin-Moo Lee, Rajat Dhar
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Quantifying the extent and evolution of cerebral edema developing after stroke is an important but challenging goal. Lesional net water uptake (NWU) is a promising CT-based biomarker of edema, but its measurement requires manually delineating infarct
Externí odkaz:
https://doaj.org/article/951566cb8c5c4e5b801450feb8f04b21
Autor:
Ping Yan, Ki-Wook Kim, Qingli Xiao, Xiucui Ma, Leah R. Czerniewski, Haiyan Liu, David R. Rawnsley, Yan Yan, Gwendalyn J. Randolph, Slava Epelman, Jin-Moo Lee, Abhinav Diwan
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 11 (2022)
Microglia, the parenchymal tissue macrophages in the brain, surround amyloid plaques in brains of individuals with Alzheimer’s disease (AD) but are ineffective at clearing amyloid to mitigate disease progression. Recent studies in mice indicate tha
Externí odkaz:
https://doaj.org/article/27704bd3066749ef9a3e3a8ea5e14f2b
Autor:
Annie R Bice, Qingli Xiao, Justin Kong, Ping Yan, Zachary Pollack Rosenthal, Andrew W Kraft, Karen P Smith, Tadeusz Wieloch, Jin-Moo Lee, Joseph P Culver, Adam Q Bauer
Publikováno v:
eLife, Vol 11 (2022)
Understanding circuit-level manipulations that affect the brain’s capacity for plasticity will inform the design of targeted interventions that enhance recovery after stroke. Following stroke, increased contralesional activity (e.g. use of the unaf
Externí odkaz:
https://doaj.org/article/481b29c3c520498a9c24f7a5de40ba55