Deconvoluting complex correlates of COVID-19 severity with a multi-omic pandemic tracking strategy

Autor: Victoria N. Parikh, Alexander G. Ioannidis, David Jimenez-Morales, John E. Gorzynski, Hannah N. De Jong, Xiran Liu, Jonasel Roque, Victoria P. Cepeda-Espinoza, Kazutoyo Osoegawa, Chris Hughes, Shirley C. Sutton, Nathan Youlton, Ruchi Joshi, David Amar, Yosuke Tanigawa, Douglas Russo, Justin Wong, Jessie T. Lauzon, Jacob Edelson, Daniel Mas Montserrat, Yongchan Kwon, Simone Rubinacci, Olivier Delaneau, Lorenzo Cappello, Jaehee Kim, Massa J. Shoura, Archana N. Raja, Nathaniel Watson, Nathan Hammond, Elizabeth Spiteri, Kalyan C. Mallempati, Gonzalo Montero-Martín, Jeffrey Christle, Jennifer Kim, Anna Kirillova, Kinya Seo, Yong Huang, Chunli Zhao, Sonia Moreno-Grau, Steven G. Hershman, Karen P. Dalton, Jimmy Zhen, Jack Kamm, Karan D. Bhatt, Alina Isakova, Maurizio Morri, Thanmayi Ranganath, Catherine A. Blish, Angela J. Rogers, Kari Nadeau, Samuel Yang, Andra Blomkalns, Ruth O’Hara, Norma F. Neff, Christopher DeBoever, Sándor Szalma, Matthew T. Wheeler, Christian M. Gates, Kyle Farh, Gary P. Schroth, Phil Febbo, Francis deSouza, Omar E. Cornejo, Marcelo Fernandez-Vina, Amy Kistler, Julia A. Palacios, Benjamin A. Pinsky, Carlos D. Bustamante, Manuel A. Rivas, Euan A. Ashley

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)

There is a genetic component to the risk of severe COVID-19, but the genetic effects are difficult to separate from social constructs that covary with genetic ancestry. To address this, the authors identify determinants of COVID-19 severity using adm

Externí odkaz: https://doaj.org/article/10002eca5587461185e42393a7dc16a5

Bilateral adrenal hemorrhage in a postpartum woman with multiple thromboemboli: A case report.

Autor: Jiang, Anna Yi Nan, Abasszade, Joshua Haron, Abrahams, Timothy, Nan, Kirollos, Low, Michael Sze Yuan, Barnes, Sara Laura, Lim, Ann Nee, Shen, Jimmy Zhen Long

Publikováno v: Journal of Medical Case Reports; 10/25/2024, Vol. 18 Issue 1, p1-7, 7p

Deconvoluting complex correlates of COVID19 severity with local ancestry inference and viral phylodynamics: Results of a multiomic pandemic tracking strategy

Autor: Kinya Seo, Jennifer Kim, Douglas Russo, David Jimenez-Morales, Lorenzo Cappello, Nathaniel Watson, Manuel A. Rivas, Archana Raja, Nathan Hammond, Marcelo Fernandez-Vina, Francis deSouza, Nathan Youlton, Steven G. Hershman, Kazutoyo Osoegawa, Olivier Delaneau, Shirley Sutton, Jessie T. Lauzon, Andra L. Blomkalns, Ruth O'Hara, Yongchan Kwon, Amy Kistler, Victoria N. Parikh, Yong Huang, Carlos Bustamante, Matthew T. Wheeler, Elizabeth Spiteri, Benjamin A. Pinsky, Jonasel Roque, Simone Rubinacci, Massa J. Shoura, Thanmayi Ranganath, Samuel Yang, John E. Gorzynski, Alina Isakova, Gary P. Schroth, Kyle Kai-How Farh, Yosuke Tanigawa, Ruchi Joshi, Hannah N. De Jong, Kalyan C. Mallempati, Catherine A. Blish, Christopher R. Hughes, Norma Neff, Justin Wong, Karan D. Bhatt, Sándor Szalma, Julia A. Palacios, Jimmy Zhen, Jack Kamm, Alexander G. Ioannidis, Anna Kirillova, Xiran Liu, Gonzalo Montero-Martín, Angela J. Rogers, Jeffrey W. Christle, David Amar, Maurizio Morri, Karen P. Dalton, Phil Febbo, Jaehee Kim, Victoria P. Cepeda-Espinoza, Sonia Moreno-Grau, Chunli Zhao, Christopher DeBoever, Euan A. Ashley, Kari C. Nadeau, Jacob Edelson, Daniel Mas Montserrat

The SARS-CoV-2 pandemic has differentially impacted populations of varied race, ethnicity and socioeconomic status. Admixture mapping and local ancestry inference represent powerful tools to examine genetic risk within multi-ancestry genomes independ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aeee66778d9fd13a5991ed041ddf74c6
https://doi.org/10.1101/2021.08.04.21261547

Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise

Autor: James A. Sanford, Christopher D. Nogiec, Malene E. Lindholm, Joshua N. Adkins, David Amar, Surendra Dasari, Jonelle K. Drugan, Facundo M. Fernández, Shlomit Radom-Aizik, Simon Schenk, Michael P. Snyder, Russell P. Tracy, Patrick Vanderboom, Scott Trappe, Martin J. Walsh, Charles R. Evans, Facundo M. Fernandez, Yafeng Li, Lyl Tomlinson, D. Lee Alekel, Iddil Bekirov, Amanda T. Boyce, Josephine Boyington, Jerome L. Fleg, Lyndon J.O. Joseph, Maren R. Laughlin, Padma Maruvada, Stephanie A. Morris, Joan A. McGowan, Concepcion Nierras, Vinay Pai, Charlotte Peterson, Ed Ramos, Mary C. Roary, John P. Williams, Ashley Xia, Elaine Cornell, Jessica Rooney, Michael E. Miller, Walter T. Ambrosius, Scott Rushing, Cynthia L. Stowe, W. Jack Rejeski, Barbara J. Nicklas, Marco Pahor, Ching-ju Lu, Todd Trappe, Toby Chambers, Ulrika Raue, Bridget Lester, Bryan C. Bergman, David H. Bessesen, Catherine M. Jankowski, Wendy M. Kohrt, Edward L. Melanson, Kerrie L. Moreau, Irene E. Schauer, Robert S. Schwartz, William E. Kraus, Cris A. Slentz, Kim M. Huffman, Johanna L. Johnson, Leslie H. Willis, Leslie Kelly, Joseph A. Houmard, Gabriel Dubis, Nick Broskey, Bret H. Goodpaster, Lauren M. Sparks, Paul M. Coen, Dan M. Cooper, Fadia Haddad, Tuomo Rankinen, Eric Ravussin, Neil Johannsen, Melissa Harris, John M. Jakicic, Anne B. Newman, Daniel D. Forman, Erin Kershaw, Renee J. Rogers, Bradley C. Nindl, Lindsay C. Page, Maja Stefanovic-Racic, Susan L. Barr, Blake B. Rasmussen, Tatiana Moro, Doug Paddon-Jones, Elena Volpi, Heidi Spratt, Nicolas Musi, Sara Espinoza, Darpan Patel, Monica Serra, Jonathan Gelfond, Aisling Burns, Marcas M. Bamman, Thomas W. Buford, Gary R. Cutter, Sue C. Bodine, Karyn Esser, Rodger P. Farrar, Laurie J. Goodyear, Michael F. Hirshman, Brent G. Albertson, Wei-Jun Qian, Paul Piehowski, Marina A. Gritsenko, Matthew E. Monore, Vladislav A. Petyuk, Jason E. McDermott, Joshua N. Hansen, Chelsea Hutchison, Samuel Moore, David A. Gaul, Clary B. Clish, Julian Avila-Pacheco, Courtney Dennis, Manolis Kellis, Steve Carr, Pierre M. Jean-Beltran, Hasmik Keshishian, D.R. Mani, Karl Clauser, Karsten Krug, Charlie Mundorff, Cadence Pearce, Anna A. Ivanova, Eric A. Ortlund, Kristal Maner-Smith, Karan Uppal, Tiantian Zhang, Stuart C. Sealfon, Elena Zaslavsky, Venugopalan Nair, SiDe Li, Nimisha Jain, YongChao Ge, Yifei Sun, German Nudelman, Frederique Ruf-zamojski, Gregory Smith, Nhanna Pincas, Aliza Rubenstein, Mary Anne Amper, Nitish Seenarine, Tuuli Lappalainen, Ian R. Lanza, K. Sreekumaran Nair, Katherine Klaus, Stephen B. Montgomery, Kevin S. Smith, Nicole R. Gay, Bingqing Zhao, Chia-Jiu Hung, Navid Zebarjadi, Brunilda Balliu, Laure Fresard, Charles F. Burant, Jun Z. Li, Maureen Kachman, Tanu Soni, Alexander B. Raskind, Robert Gerszten, Jeremy Robbins, Olga Ilkayeva, Michael J. Muehlbauer, Christopher B. Newgard, Euan A. Ashley, Matthew T. Wheeler, David Jimenez-Morales, Archana Raja, Karen P. Dalton, Jimmy Zhen, Young Suk Kim, Jeffrey W. Christle, Shruti Marwaha, Elizabeth T. Chin, Steven G. Hershman, Trevor Hastie, Robert Tibshirani, Manuel A. Rivas

Publikováno v: Cell

Exercise provides a robust physiological stimulus that evokes cross-talk among multiple tissues that when repeated regularly (i.e., training) improves physiological capacity, benefits numerous organ systems, and decreases the risk for premature morta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a9f392d30205cd12c1ad5de94f934d
http://hdl.handle.net/11577/3371085

Patient Representativeness With Virtual Enrollment in the PRO‐HF Trial

Autor: Anshal Gupta, Megan Skye, Jamie Calma, Natasha Din, Zahra Azizi, Mario Funes Hernandez, Jimmy Zheng, Neil M. Kalwani, Sanjay Malunjkar, Jessica Schirmer, Paul Wang, Fatima Rodriguez, Paul Heidenreich, Alexander T. Sandhu

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 2 (2024)

Externí odkaz: https://doaj.org/article/34226d4e08304ae2ba2ab7f5938be47a