Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jimmy Y. C. Chow"'
Autor:
Tobias Xiao Dong, Hui Dong, Shi Ming Yang, De Sheng Lu, Bo Tang, John M. Carethers, Jimmy Y. C. Chow
Publikováno v:
Cancer Letters. 377:44-54
The calcium sensing receptor (CaSR) is functionally expressed in normal human pancreases, but its pathological role in pancreatic tumorigenesis is currently unknown. We sought to investigate the role of CaSR in pancreatic cancer (PC) and the underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f054af07c3253eaad75b7769ff71f264
https://doi.org/10.1016/j.canlet.2016.04.027
https://doi.org/10.1016/j.canlet.2016.04.027
Autor:
Xue Wang, Hui Dong, Volker Vallon, Huichao Wu, Guorong Wen, Xuemei Liu, Yalin Zhang, Xiao Dong, Biguang Tuo, Jinqi Wei, Jimmy Y. C. Chow
Publikováno v:
Gastroenterology. 141:854-863
Background & Aims The reason that women have a lower prevalence of duodenal ulcer is not clear. We investigated whether estrogen regulates human duodenal bicarbonate secretion (DBS) and whether this process accounts for sex differences in the prevale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a083c73987ce1170884a792ee99420f5
https://doi.org/10.1053/j.gastro.2011.05.044
https://doi.org/10.1053/j.gastro.2011.05.044
Publikováno v:
American Journal of Physiology-Cell Physiology. 301:C461-C468
Ca-sensing receptor (CaSR), a member of the G protein-coupled receptor family, regulates the synthesis of parathyroid hormone in response to changes in serum Ca2+ concentrations. The functions of CaSR in human vascular smooth muscle cells are largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f56244b4368018ef7100fa669e6adf5
https://doi.org/10.1152/ajpcell.00389.2010
https://doi.org/10.1152/ajpcell.00389.2010
Autor:
Tiffany A. Ornelas, Flang Nguyen, Sonia Ramamoorthy, Samuel B. Ho, Shanglei Liu, Christine L. Estrema, Ki Nam Shim, Hui Dong, John M. Carethers, Jenny M. J. Li, Jimmy Y. C. Chow
Publikováno v:
American Journal of Physiology-Cell Physiology. 299:C1493-C1503
We recently reported that transforming growth factor-β (TGF-β) induces an increase in cytosolic Ca2+([Ca2+]cyt) in pancreatic cancer cells, but the mechanisms by which TGF-β mediates [Ca2+]cythomeostasis in these cells are currently unknown. Trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14fdc0a3b3eccd8129d1bb1084a6f91f
https://doi.org/10.1152/ajpcell.00242.2010
https://doi.org/10.1152/ajpcell.00242.2010
Publikováno v:
Acta Physiologica. 201:97-107
Although acid-sensing ion channels (ASICs) have been studied in a variety of mammalian cells, little is currently known about their presence in intestinal epithelial cells. Therefore, the aims of the present study were to investigate the expression a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dead846800f17d6bd1eda1870c72cab0
https://doi.org/10.1111/j.1748-1716.2010.02207.x
https://doi.org/10.1111/j.1748-1716.2010.02207.x
Autor:
John M. Carethers, Mei Huang, Makiko Ban, Heekyung Chung, Helen L. Wu, Flang Nguyen, Jimmy Y. C. Chow, Hui Dong
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 298:G275-G282
TGF-beta utilizes receptor-activated SMAD signaling to mediate growth suppression; however, non-SMAD signaling that modulates the TGF-beta response in epithelial cells become apparent when the SMAD signaling is abrogated, a common occurrence in pancr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91c601b54ed5d02c60353f96fabcf70
https://doi.org/10.1152/ajpgi.00344.2009
https://doi.org/10.1152/ajpgi.00344.2009
Autor:
Jimmy Y. C. Chow, Eric J. Smoll, Xiao Dong, Paul A. Insel, Jonathan Lee, Hui Dong, Kwang Hyun Ko, Hong Dong Kim
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 296:G424-G432
Since little is known about the role of P2Y receptors (purinoceptors) in duodenal mucosal bicarbonate secretion (DMBS), we sought to investigate the expression and function of these receptors in duodenal epithelium. Expression of P2Y2receptors was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::721f94b383ebca8ac88459c3d7e99e61
https://doi.org/10.1152/ajpgi.90314.2008
https://doi.org/10.1152/ajpgi.90314.2008
Publikováno v:
Journal of Organ Dysfunction. 4:249-256
Firstly, we have to thank the Nobel Prize winners of Physiology or Medicine 2006, Drs. Andrew Fire at Stanford University and Craig Mello at the University of Massachusetts Medical School, for their pioneering work in RNA interference (RNAi). Without
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47b7a7f6c7a5f776e09259b2ea7b7724
https://doi.org/10.1080/17471060701275354
https://doi.org/10.1080/17471060701275354
Autor:
Jimmy Y. C. Chow, Betty L. Cabrera, Stayce E. Beck, Khai T. Quach, Jennifer Cabral, John M. Carethers
Publikováno v:
Carcinogenesis. 28:2321-2327
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is rarely mutated in pancreatic cancers, but its regulation by transforming growth factor (TGF)-beta might mediate growth suppression and other oncogenic actions. Here, we examined the ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb2fb28dcfb9d664c96695278aeb4d2
https://doi.org/10.1093/carcin/bgm159
https://doi.org/10.1093/carcin/bgm159
Autor:
Zachary M. Sellers, Kim E. Barrett, Anders Smith, Jon I. Isenberg, Hui Dong, Vijaya S. Pratha, Daniel L. Hogan, Jimmy Y. C. Chow, Debbie Childs
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 288:G654-G663
The cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is an important pathway for duodenal mucosal bicarbonate secretion. Duodenal biopsies from CF patients secrete bicarbonate in response to heat-stable enterotoxin from Escherichia col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbc6cd441456db3ad1d8c58c9e08c11
https://doi.org/10.1152/ajpgi.00386.2004
https://doi.org/10.1152/ajpgi.00386.2004