Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jimmy Vandel"'
Autor:
Manuel Johanns, Joel T. Haas, Violetta Raverdy, Jimmy Vandel, Julie Chevalier-Dubois, Loic Guille, Bruno Derudas, Benjamin Legendre, Robert Caiazzo, Helene Verkindt, Viviane Gnemmi, Emmanuelle Leteurtre, Mehdi Derhourhi, Amélie Bonnefond, Philippe Froguel, Jérôme Eeckhoute, Guillaume Lassailly, Philippe Mathurin, François Pattou, Bart Staels, Philippe Lefebvre
Publikováno v:
JHEP Reports, Vol 6, Iss 1, Pp 100948- (2024)
Background & Aims: Liver homeostasis is ensured in part by time-of-day-dependent processes, many of them being paced by the molecular circadian clock. Liver functions are compromised in metabolic dysfunction-associated steatotic liver disease (MASLD)
Externí odkaz:
https://doaj.org/article/4fd9fffee41d4c35be393a757aed20a5
Autor:
Marie Bobowski-Gerard, Clémence Boulet, Francesco P. Zummo, Julie Dubois-Chevalier, Céline Gheeraert, Mohamed Bou Saleh, Jean-Marc Strub, Amaury Farce, Maheul Ploton, Loïc Guille, Jimmy Vandel, Antonino Bongiovanni, Ninon Very, Eloïse Woitrain, Audrey Deprince, Fanny Lalloyer, Eric Bauge, Lise Ferri, Line-Carolle Ntandja-Wandji, Alexia K. Cotte, Corinne Grangette, Emmanuelle Vallez, Sarah Cianférani, Violeta Raverdy, Robert Caiazzo, Viviane Gnemmi, Emmanuelle Leteurtre, Benoit Pourcet, Réjane Paumelle, Kim Ravnskjaer, Guillaume Lassailly, Joel T. Haas, Philippe Mathurin, François Pattou, Laurent Dubuquoy, Bart Staels, Philippe Lefebvre, Jérôme Eeckhoute
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Myofibroblasts contribute to the development of liver fibrosis. Here, the authors report that the transcription factor Basonuclin 2 (BNC2) integrates fibrogenic signals and drives myofibroblastic transcriptional activation in liver fibrosis.
Externí odkaz:
https://doaj.org/article/c0d2d56ec91641b79809fad780054395
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-19 (2019)
Abstract Background In eukaryotic cells, transcription factors (TFs) are thought to act in a combinatorial way, by competing and collaborating to regulate common target genes. However, several questions remain regarding the conservation of these comb
Externí odkaz:
https://doaj.org/article/fd2b361361c44948afa90145523d6583
Autor:
Chloé Bessière, May Taha, Florent Petitprez, Jimmy Vandel, Jean-Michel Marin, Laurent Bréhélin, Sophie Lèbre, Charles-Henri Lecellier
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005921 (2018)
Gene expression is orchestrated by distinct regulatory regions to ensure a wide variety of cell types and functions. A challenge is to identify which regulatory regions are active, what are their associated features and how they work together in each
Externí odkaz:
https://doaj.org/article/4364bca7da2c4e7485c066e824dc79f0
Autor:
Matthieu Vignes, Jimmy Vandel, David Allouche, Nidal Ramadan-Alban, Christine Cierco-Ayrolles, Thomas Schiex, Brigitte Mangin, Simon de Givry
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29165 (2011)
Modern technologies and especially next generation sequencing facilities are giving a cheaper access to genotype and genomic data measured on the same sample at once. This creates an ideal situation for multifactorial experiments designed to infer ge
Externí odkaz:
https://doaj.org/article/2d2e2f02a9cc423fbe86a074c86740ce
Autor:
Manuel Johanns, Joel T. Haas, Violetta Raverdy, Jimmy Vandel, Julie Chevalier-Dubois, Loic Guille, Bruno Derudas, Benjamin Legendre, Robert Caiazzo, Helene Verkindt, Viviane Gnemmi, Emmanuelle Leteurtre, Mehdi Derhourhi, Amélie Bonnefond, Philippe Froguel, Jérôme Eeckhoute, Guillaume Lassailly, Philippe Mathurin, François Pattou, Bart Staels, Philippe Lefebvre
Liver homeostasis is ensured in part by time-of-day-dependent processes, many of them being paced by the molecular circadian clock. Liver functions are compromised in non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH), and cloc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82428bc2b02da8b5af2a3b389dba340b
https://doi.org/10.1101/2023.04.05.535334
https://doi.org/10.1101/2023.04.05.535334
Publikováno v:
BMC Genomics
BMC Genomics, BioMed Central, 2019, 20 (103), ⟨10.1186/s12864-018-5408-0⟩
BMC Genomics, 2019, 20 (103), ⟨10.1186/s12864-018-5408-0⟩
BMC Genomics, Vol 20, Iss 1, Pp 1-19 (2019)
BMC Genomics, BioMed Central, 2019, 20 (103), ⟨10.1186/s12864-018-5408-0⟩
BMC Genomics, 2019, 20 (103), ⟨10.1186/s12864-018-5408-0⟩
BMC Genomics, Vol 20, Iss 1, Pp 1-19 (2019)
Background In eukaryotic cells, transcription factors (TFs) are thought to act in a combinatorial way, by competing and collaborating to regulate common target genes. However, several questions remain regarding the conservation of these combinations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8281af3042e8d0866e09acc54c9046f7
https://hal.archives-ouvertes.fr/hal-02070201/file/s12864-018-5408-0.pdf
https://hal.archives-ouvertes.fr/hal-02070201/file/s12864-018-5408-0.pdf
Autor:
May Taha, Chloé Bessière, Florent Petitprez, Jimmy Vandel, Jean-Michel Marin, Laurent Brehelin, Sophie Lébre, Charles-Henri Lecellier
Publikováno v:
JdS 2017, 49èmes Journées de Statistique de la SFdS
JdS 2017, 49èmes Journées de Statistique de la SFdS, May 2017, Avignon, France
HAL
JdS 2017, 49èmes Journées de Statistique de la SFdS, May 2017, Avignon, France
HAL
International audience; Gene expression is tightly controlled to ensure a wide variety of cell types and functions. The development of diseases, particularly cancers, is invariably related to deregulations of these controls. Our objective is to model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::06e6799a325dd5ecfcc6ca9b203eccc0
https://hal.archives-ouvertes.fr/hal-02068289/file/abstract_SFDS.pdf
https://hal.archives-ouvertes.fr/hal-02068289/file/abstract_SFDS.pdf
Autor:
Sophie Lèbre, May Taha, Laurent Bréhélin, Chloé Bessière, Florent Petitprez, Charles-Henri Lecellier, Jimmy Vandel, Jean-Michel Marin
Gene expression is orchestrated by distinct regulatory regions (e.g. promoters, enhancers, UTRs) to ensure a wide variety of cell types and functions. A challenge is to identify which regulatory regions are active, what are their associated features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1953a93168f9f6667a3068de642091
https://doi.org/10.1101/117499
https://doi.org/10.1101/117499
SAGA: Sparse And Geometry-Aware non-negative matrix factorization through non-linear local embedding
Publikováno v:
Machine Learning
Machine Learning, Springer Verlag, 2014, pp.1--23
Machine Learning, Springer Verlag, 2014, 97 (1-2), pp.205-226. ⟨10.1007/s10994-014-5463-y⟩
Machine Learning, 2014, pp.1--23
Machine Learning, 2014, 97 (1-2), pp.205-226. ⟨10.1007/s10994-014-5463-y⟩
HAL
Machine Learning, Springer Verlag, 2014, pp.1--23
Machine Learning, Springer Verlag, 2014, 97 (1-2), pp.205-226. ⟨10.1007/s10994-014-5463-y⟩
Machine Learning, 2014, pp.1--23
Machine Learning, 2014, 97 (1-2), pp.205-226. ⟨10.1007/s10994-014-5463-y⟩
HAL
International audience; This paper presents a new non-negative matrix factorization technique which (1) allows the decomposition of the original data on multiple latent factors accounting for the geometrical structure of the manifold embedding the da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6fc1276b6d96f12b269ba89a57e256
https://hal.archives-ouvertes.fr/hal-01018683/file/SAGA.pdf
https://hal.archives-ouvertes.fr/hal-01018683/file/SAGA.pdf