Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Jimmy Larsson"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Rapid antibiotic susceptibility testing (AST) is needed. Here the authors report a method for phenotypic AST at the single cell level, using a microfluidic chip that allows for subsequent genotyping with in situ FISH; they apply this to a mixed sampl
Externí odkaz:
https://doaj.org/article/28f5f838d7d04d78a148d3f67e4d8c05
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Bacterial populations can show heteroresistance, where an antibiotic resistant subpopulation is part of a susceptible one. Pereira et al. show in Escherichia coli and Salmonella enterica that disk diffusion, a common antibiotic susceptibility test, u
Externí odkaz:
https://doaj.org/article/30d04637977e4da795b0806423d91630
Autor:
Snehangshu Kundu, Muhammad Akhtar Ali, Niklas Handin, Narendra Padhan, Jimmy Larsson, Maria Karoutsou, Kenneth Ban, Jacek R. Wiśniewski, Per Artursson, Liqun He, Mats Hellström, Tobias Sjöblom
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-13 (2018)
Abstract Background The Ras pathway genes KRAS, BRAF, or ERBBs have somatic mutations in ~ 60% of human colorectal carcinomas. At present, it is unknown whether the remaining cases lack mutations activating the Ras pathway or whether they have acquir
Externí odkaz:
https://doaj.org/article/e59e8395c9b944bfa4183f634a16c9e7
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 10, Pp 1-9 (2017)
Abstract In this work, we present a proof‐of‐principle experiment that extends advanced live cell microscopy to the scale of pool‐generated strain libraries. We achieve this by identifying the genotypes for individual cells in situ after a deta
Externí odkaz:
https://doaj.org/article/22be1022854d42a69295b67df6e9e810
Autor:
Anders R Hellström, Brenda Watt, Shahrzad Shirazi Fard, Danièle Tenza, Paula Mannström, Kristina Narfström, Björn Ekesten, Shosuke Ito, Kazumasa Wakamatsu, Jimmy Larsson, Mats Ulfendahl, Klas Kullander, Graça Raposo, Susanne Kerje, Finn Hallböök, Michael S Marks, Leif Andersson
Publikováno v:
PLoS Genetics, Vol 7, Iss 9, p e1002285 (2011)
PMEL is an amyloidogenic protein that appears to be exclusively expressed in pigment cells and forms intralumenal fibrils within early stage melanosomes upon which eumelanins deposit in later stages. PMEL is well conserved among vertebrates, and alle
Externí odkaz:
https://doaj.org/article/421f79eca213475d87b146fc6194252f
Autor:
Mats Hellström, Tobias Sjöblom, Richard Rosenquist, Larry Mansouri, Viktor Ljungström, Elias Campo, Armando Lopez-Guillermo, Tycho Baumann, Jonathan C. Strefford, Stuart J. Blakemore, Ruth Clifford, Anna Schuh, Anders R. Hellström, Muhammad Akhtar-Ali, Kenneth Ban, Snehangshu Kundu, Liqun He, Jimmy Larsson, Tatjana Pandzic
Purpose: To identify resistance mechanisms for the chemotherapeutic drug fludarabine in chronic lymphocytic leukemia (CLL), as innate and acquired resistance to fludarabine-based chemotherapy represents a major challenge for long-term disease control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03eb50fe7e3a128ab05509a118edd6ba
https://doi.org/10.1158/1078-0432.c.6526932
https://doi.org/10.1158/1078-0432.c.6526932
Autor:
Mats Hellström, Tobias Sjöblom, Richard Rosenquist, Larry Mansouri, Viktor Ljungström, Elias Campo, Armando Lopez-Guillermo, Tycho Baumann, Jonathan C. Strefford, Stuart J. Blakemore, Ruth Clifford, Anna Schuh, Anders R. Hellström, Muhammad Akhtar-Ali, Kenneth Ban, Snehangshu Kundu, Liqun He, Jimmy Larsson, Tatjana Pandzic
Supplementary Material and Methods in Word format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e898d2b69f3bff47f3c7766d484c02
https://doi.org/10.1158/1078-0432.22468431
https://doi.org/10.1158/1078-0432.22468431
Autor:
Mats Hellström, Tobias Sjöblom, Richard Rosenquist, Larry Mansouri, Viktor Ljungström, Elias Campo, Armando Lopez-Guillermo, Tycho Baumann, Jonathan C. Strefford, Stuart J. Blakemore, Ruth Clifford, Anna Schuh, Anders R. Hellström, Muhammad Akhtar-Ali, Kenneth Ban, Snehangshu Kundu, Liqun He, Jimmy Larsson, Tatjana Pandzic
Supplementary Figure S1. schematic illustration of piggyBac transposon and transposase vectors used. PB IR refers to piggyBac inverted repeats. FRT is flippase recognition target. Supplementary Figure S2. Real-time quantitative PCR analysis confirms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8bf4763b81377a72591287b5172981
https://doi.org/10.1158/1078-0432.22468434
https://doi.org/10.1158/1078-0432.22468434
Autor:
Mats Hellström, Tobias Sjöblom, Richard Rosenquist, Larry Mansouri, Viktor Ljungström, Elias Campo, Armando Lopez-Guillermo, Tycho Baumann, Jonathan C. Strefford, Stuart J. Blakemore, Ruth Clifford, Anna Schuh, Anders R. Hellström, Muhammad Akhtar-Ali, Kenneth Ban, Snehangshu Kundu, Liqun He, Jimmy Larsson, Tatjana Pandzic
supplemental figure and table legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6668dfdac49855f143e7bbae336868c6
https://doi.org/10.1158/1078-0432.22468428
https://doi.org/10.1158/1078-0432.22468428
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The rise of antibiotic-resistant bacterial infections poses a global threat. Antibiotic resistance development is generally studied in batch cultures which conceals the heterogeneity in cellular responses. Using single-cell imaging, we studied the gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd33103427af58b98b6be838b72ef19
https://doi.org/10.1073/pnas.2216216120
https://doi.org/10.1073/pnas.2216216120