Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jimmy L Zhao"'
Autor:
Robert B Lochhead, Ying Ma, James F Zachary, David Baltimore, Jimmy L Zhao, John H Weis, Ryan M O'Connell, Janis J Weis
Publikováno v:
PLoS Pathogens, Vol 10, Iss 6, p e1004212 (2014)
MicroRNAs have been shown to be important regulators of inflammatory and immune responses and are implicated in several immune disorders including systemic lupus erythematosus and rheumatoid arthritis, but their role in Lyme borreliosis remains unkno
Externí odkaz:
https://doaj.org/article/0e38995a17b74823a99f730f607094b6
Publikováno v:
eLife, Vol 2 (2013)
During inflammation and infection, hematopoietic stem and progenitor cells are stimulated to proliferate and differentiate into mature immune cells, especially of the myeloid lineage. MicroRNA-146a (miR-146a) is a critical negative regulator of infla
Externí odkaz:
https://doaj.org/article/bb1ca122fc784a52b8f89a38fa3a1437
Autor:
Joseph M. Chan, Samir Zaidi, Jillian R. Love, Jimmy L. Zhao, Manu Setty, Kristine M. Wadosky, Anuradha Gopalan, Zi-Ning Choo, Sitara Persad, Jungmin Choi, Justin LaClair, Kayla E. Lawrence, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Irina Linkov, Shangqian Wang, Cindy Lee, Afsar Barlas, Michael J. Morris, Linas Mazutis, Ronan Chaligne, Yu Chen, David W. Goodrich, Wouter R. Karthaus, Dana Pe’er, Charles L. Sawyers
Publikováno v:
Science
Drug resistance in cancer is often linked to changes in tumor cell state or lineage, but the molecular mechanisms driving this plasticity remain unclear. Using murine organoid and genetically engineered mouse models, we investigated the causes of lin
Autor:
Mati Mann, Arnav Mehta, Jimmy L. Zhao, Kevin Lee, Georgi K. Marinov, Yvette Garcia-Flores, Li-Fan Lu, Alexander Y. Rudensky, David Baltimore
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
MicroRNAs (miR) are important regulators of gene transcription, with miR-155 and miR-146a both implicated in macrophage activation. Here the authors show that NF-κB signalling, miR-155 and miR-146a form a complex network of cross-regulations to cont
Externí odkaz:
https://doaj.org/article/4ae78de76bc742c580b294dc0c5d59fe
Autor:
Alexander Pan, Rachel E. Reingold, Jimmy L. Zhao, Andrea Moy, Lukas Kraehenbuehl, George Dranitsaris, Sean M. McBride, Howard I. Scher, Marisa A. Kollmeier, Han Xiao, Dana E. Rathkopf, Mario E. Lacouture
Publikováno v:
J Urol
PURPOSE: Prostate cancer (PCa) patients treated with apalutamide frequently develop rash. We aim to characterize apalutamide-related dermatologic adverse events (dAE) and management. MATERIALS AND METHODS: We assessed 303 PCa patients treated with ap
Autor:
Dan Li, Yu Zhan, Naitao Wang, Fanying Tang, Cindy J. Lee, Gabriella Bayshtok, Amanda R. Moore, Elissa W. P. Wong, Mohini R. Pachai, Yuanyuan Xie, Jessica Sher, Jimmy L. Zhao, Makhzuna Khudoynazarova, Anuradha Gopalan, Joseph Chan, Ekta Khurana, Peter Shepherd, Nora M. Navone, Ping Chi, Yu Chen
Publikováno v:
Science Advances. 9
The mechanisms underlying ETS -driven prostate cancer initiation and progression remain poorly understood due to a lack of model systems that recapitulate this phenotype. We generated a genetically engineered mouse with prostate-specific expression o
Autor:
Howard I. Scher, William T. Duggan, Johann S. de Bono, Andrew J. Armstrong, Cora N. Sternberg, Mary-Ellen Taplin, Kim N. Chi, Fred Saad, Karim Fizazi, Jimmy L. Zhao
Purpose:The clinical impact of concurrent corticosteroid use (CCU) on enzalutamide-treated patients with metastatic castration-resistant prostate cancer (mCRPC) is unknown. We investigated the association of CCU with overall survival (OS), radiograph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ca114c2cf517cbe1559e144ed24d34
https://doi.org/10.1158/1078-0432.c.6531342.v1
https://doi.org/10.1158/1078-0432.c.6531342.v1
Autor:
Howard I. Scher, William T. Duggan, Johann S. de Bono, Andrew J. Armstrong, Cora N. Sternberg, Mary-Ellen Taplin, Kim N. Chi, Fred Saad, Karim Fizazi, Jimmy L. Zhao
Supplementary Table from The Effect of Corticosteroids on Prostate Cancer Outcome Following Treatment with Enzalutamide: A Multivariate Analysis of the Phase III AFFIRM Trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b1315295c5361403adb1c057b079ef
https://doi.org/10.1158/1078-0432.22484148.v1
https://doi.org/10.1158/1078-0432.22484148.v1
Autor:
Howard I. Scher, William T. Duggan, Johann S. de Bono, Andrew J. Armstrong, Cora N. Sternberg, Mary-Ellen Taplin, Kim N. Chi, Fred Saad, Karim Fizazi, Jimmy L. Zhao
Supplementary Figure from The Effect of Corticosteroids on Prostate Cancer Outcome Following Treatment with Enzalutamide: A Multivariate Analysis of the Phase III AFFIRM Trial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ba4fbf6179daf5971a52e48a90211d
https://doi.org/10.1158/1078-0432.22484151.v1
https://doi.org/10.1158/1078-0432.22484151.v1
Autor:
Andrew J. Armstrong, Howard I. Scher, Daniel J. George, Emmanuel S. Antonarakis, Richard Wenstrup, Simon G. Gregory, Santosh Gupta, William R. Berry, Adam Jendrisak, Audrey Gill, Monika Anand, Patrick Healy, Jimmy L. Zhao, Emily A. Carbone, Ethan S. Barnett, Daniel C. Danila, Russell Z. Szmulewitz, Paraskevi Giannakakou, David M. Nanus, Jun Luo, Qian Yang, Joseph D. Schonhoft, Susan Halabi, Landon C. Brown
Purpose:While the detection of AR-V7 in circulating tumor cells (CTC) is associated with resistance to abiraterone or enzalutamide in men with metastatic castration-resistant prostate cancer (mCRPC), it only accounts for a minority of this resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58fe58cebd742835e86089d1f77fa2c0
https://doi.org/10.1158/1078-0432.c.6530474
https://doi.org/10.1158/1078-0432.c.6530474