Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Jimmy K Eng"'
Autor:
Juan D Chavez, Jimmy K Eng, Devin K Schweppe, Michelle Cilia, Keith Rivera, Xuefei Zhong, Xia Wu, Terrence Allen, Moshe Khurgel, Akhilesh Kumar, Athanasios Lampropoulos, Mårten Larsson, Shuvadeep Maity, Yaroslav Morozov, Wimal Pathmasiri, Mathew Perez-Neut, Coriness Pineyro-Ruiz, Elizabeth Polina, Stephanie Post, Mark Rider, Dorota Tokmina-Roszyk, Katherine Tyson, Debora Vieira Parrine Sant'Ana, James E Bruce
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167547 (2016)
Chemical cross-linking mass spectrometry (XL-MS) provides protein structural information by identifying covalently linked proximal amino acid residues on protein surfaces. The information gained by this technique is complementary to other structural
Externí odkaz:
https://doaj.org/article/3ba39bd136884daab38534c011a3f079
Autor:
Ian R. Smith, Jimmy K. Eng, Anthony S. Barente, Alexander Hogrebe, Ariadna Llovet, Ricard A. Rodriguez-Mias, Judit Villén
Publikováno v:
Analytical Chemistry. 94:15198-15206
SILAC-based metabolic labeling is a widely adopted proteomics approach that enables quantitative comparisons among a variety of experimental conditions. Despite its quantitative capacity, SILAC experiments analyzed with data dependent acquisition (DD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c59d9c3c6063eee2b624882d029831
https://doi.org/10.1021/acs.analchem.2c01711
https://doi.org/10.1021/acs.analchem.2c01711
Autor:
Xia Wu, Juan D. Chavez, Devin K. Schweppe, Chunxiang Zheng, Chad R. Weisbrod, Jimmy K. Eng, Ananya Murali, Samuel A. Lee, Elizabeth Ramage, Larry A. Gallagher, Hemantha D. Kulasekara, Mauna E. Edrozo, Cassandra N. Kamischke, Mitchell J. Brittnacher, Samuel I. Miller, Pradeep K. Singh, Colin Manoil, James E. Bruce
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The bacterial pathogen Acinetobacter baumannii has evolved resistance to many antibiotics, including carbapenems. Here, Wu et al. show that the carbapenemase Oxa-23 interacts with the outer membrane porin CarO in an A. baumanniiisolate, indicative of
Externí odkaz:
https://doaj.org/article/1333b90e086549de845305809266c010
Autor:
Eric W. Deutsch, Luis Mendoza, David D. Shteynberg, Michael R. Hoopmann, Zhi Sun, Jimmy K. Eng, Robert L. Moritz
Publikováno v:
J Proteome Res
The Trans-Proteomic Pipeline mass spectrometry data analysis suite has been in continual development and refinement since its first tools PeptideProphet and ProteinProphet were published twenty years ago. The current release provides a large compleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d78596ea0049f81423b7346c316b99
https://europepmc.org/articles/PMC10166710/
https://europepmc.org/articles/PMC10166710/
Autor:
Attila Kertesz-Farkas, Frank Lawrence Nii Adoquaye Acquaye, Kishankumar Bhimani, Jimmy K. Eng, William E. Fondrie, Charles Grant, Michael R. Hoopmann, Andy Lin, Yang Y. Lu, Robert L. Moritz, Michael J. MacCoss, William Stafford Noble
Publikováno v:
J Proteome Res
The Crux tandem mass spectrometry data analysis toolkit provides a collection of algorithms for analyzing bottom-up proteomics tandem mass spectrometry data. Many publications have described various individual components of Crux, but a comprehensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13d84e302771bd345ffba29ac556b8c
https://doi.org/10.1101/2022.10.02.510538
https://doi.org/10.1101/2022.10.02.510538
Autor:
Jimmy K. Eng, Xuefei Zhong, Andrew Keller, Devin K. Schweppe, Martin Mathay, Xia Wu, Juan D. Chavez, James E. Bruce
Publikováno v:
J Am Soc Mass Spectrom
Molecular interactions between two different classes of β-lactamase enzymes and outer membrane protein A (OmpA) were studied by in vivo chemical cross-linking of a multi-drug-resistant strain of Acinetobacter baumannii AB5075. Class A β-lactamase b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7628985e9f86e12301e1fb0920d769b2
https://doi.org/10.1021/jasms.9b00021
https://doi.org/10.1021/jasms.9b00021
Autor:
Xia Wu, Jayanthi Garudathri, Jimmy K. Eng, Pradeep K. Singh, Colin Manoil, Egon A. Ozer, Katherine B. Hisert, Benjamin J. Staudinger, Alan R. Hauser, James E. Bruce, Richard Siehnel
Publikováno v:
Journal of Proteome Research. 18:2601-2612
Chronic airway infection with P. aeruginosa (PA) is a hallmark of cystic fibrosis (CF) disease. The mechanisms producing PA persistence in CF therapies remain poorly understood. To gain insight on PA physiology in patient airways and better understan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f13d363dd99475a33272cf5a1d5e71
https://doi.org/10.1021/acs.jproteome.9b00122
https://doi.org/10.1021/acs.jproteome.9b00122
Autor:
Vladimir Vigdorovich, Eric W. Deutsch, Kristian E. Swearingen, D. Noah Sather, Luis Mendoza, Robert L. Moritz, Jimmy K. Eng, Timothy A. Springer, Stefan H. I. Kappe, David Shteynberg
Publikováno v:
Journal of Proteome Research. 18:652-663
Thrombospondin type 1 repeats (TSRs), small adhesive protein domains with a wide range of functions, are usually modified with O-linked fucose, which may be extended to O-fucose-β1,3-glucose. Collision-induced dissociation (CID) spectra of O-fucosyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f586686b7d975fc26df694ec00437138
https://doi.org/10.1021/acs.jproteome.8b00638
https://doi.org/10.1021/acs.jproteome.8b00638
Publikováno v:
Journal of Proteome Research. 18:753-758
In cells, intra- and inter-molecular interactions of proteins confer function and the dynamic modulation of this interactome is critical to meet changing needs required to support life. Cross-linking and mass spectrometry (XL-MS) enable detection of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7760d31fc0cfb0a84bae0c85535633e
https://doi.org/10.1021/acs.jproteome.8b00703
https://doi.org/10.1021/acs.jproteome.8b00703
Autor:
Y Shi, Jan-Marino Ramirez, Nicholas P. Poolos, Jimmy K. Eng, Jeffrey G. Ojemann, M.N. Khan, F.A. Concepcion, Aguan Wei, J-D Ju Wang, Andrew L. Ko
Publikováno v:
Neuroscience
Because hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels modulate the excitability of cortical and hippocampal principal neurons, these channels play a key role in the hyperexcitability that occurs during the development of epil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc306a4a637ecaaa605c059a8b832b03
https://pubmed.ncbi.nlm.nih.gov/33571596
https://pubmed.ncbi.nlm.nih.gov/33571596