Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jimmy J Fraigne"'
Publikováno v:
SLEEP.
Research into sleep–wake behaviors relies on scoring sleep states, normally done by manual inspection of electroencephalogram (EEG) and electromyogram (EMG) recordings. This is a highly time-consuming process prone to inter-rater variability. When
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79d1a8cbd99b1499ff8f6f6f5b2fd446
https://doi.org/10.1093/sleep/zsad101
https://doi.org/10.1093/sleep/zsad101
Publikováno v:
Current Biology. 33:1550-1564.e5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27e3876ad5b3e6867a52445e289f93c1
https://doi.org/10.1016/j.cub.2023.03.077
https://doi.org/10.1016/j.cub.2023.03.077
Publikováno v:
Current biology : CB. 31(7)
Despite intensive research efforts, biologists still do not have a clear picture of the brain circuitry that controls behavioural arousal. However, new research has identified a novel septo-hypothalamic circuit that functions to promote wakefulness.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1957389438940b4714445c53f3044dbb
https://pubmed.ncbi.nlm.nih.gov/33545041
https://pubmed.ncbi.nlm.nih.gov/33545041
Publikováno v:
Sleep. 44:A2-A3
Introduction Narcolepsy is a neurological disorder that is characterized by the loss of orexin neurons in the lateral hypothalamus. Cataplexy is a symptom of narcolepsy and is identified by a sudden loss of muscle tone during wakefulness. Cataplexy a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f95f8ab1beeff7d1c298c6639adc978
https://doi.org/10.1093/sleep/zsab072.005
https://doi.org/10.1093/sleep/zsab072.005
Publikováno v:
Current biology : CB. 29(22)
Appropriate levels of muscle tone are needed to support waking behaviors such as sitting or standing. However, it is unclear how the brain functions to couple muscle tone with waking behaviors. Cataplexy is a unique experiment of nature in which musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa889eaa6d87a8010ea7cae49c214eae
https://pubmed.ncbi.nlm.nih.gov/31679942
https://pubmed.ncbi.nlm.nih.gov/31679942
Autor:
Hannah E. Bowrey, William D. Todd, Satvinder Kaur, Anne Venner, Christelle Anaclet, Ada Eban-Rothschild, Jimmy J. Fraigne
Publikováno v:
Sleep. 42
Optogenetics and chemogenetics are powerful tools, allowing the specific activation or inhibition of targeted neuronal subpopulations. Application of these techniques to sleep and circadian research has resulted in the unveiling of several neuronal p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107a5feaa42a4a467bca6596cb3f7558
https://doi.org/10.1093/sleep/zsz023
https://doi.org/10.1093/sleep/zsz023
Autor:
Richard L. Horner, Jimmy J. Fraigne, Jennifer L. Lapierre, Gaspard Montandon, Hattie Liu, John H. Peever, Zoltan A. Torontali, Garret A. Horton, Matthew B. Snow
Publikováno v:
Scientific Reports
Reduced tongue muscle tone precipitates obstructive sleep apnea (OSA), and activation of the tongue musculature can lessen OSA. The hypoglossal motor nucleus (HMN) innervates the tongue muscles but there is no pharmacological agent currently able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0e981ee9ca57a2f1b99d174b78974e
https://doi.org/10.1038/srep45860
https://doi.org/10.1038/srep45860
Autor:
Jimmy J. Fraigne, John Orem
Publikováno v:
Sleep. 34:425-434
Objectives In this study, we quantified the profiles of phasic activity in respiratory muscles (diaphragm, genioglossus and external intercostal) and non-respiratory muscles (neck and extensor digitorum) across REM sleep. We hypothesized that if ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81305004d2c89b61bba9d1632f72cb0
https://doi.org/10.1093/sleep/34.4.425
https://doi.org/10.1093/sleep/34.4.425
Autor:
Victoria L. Chuen, Gabrielle Thibault-Messier, Matthew B. Snow, Aren Thomasian, Richard L. Horner, Jimmy J. Fraigne, John H. Peever
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 37(15)
Cataplexy is a hallmark of narcolepsy characterized by the sudden uncontrollable onset of muscle weakness or paralysis during wakefulness. It can occur spontaneously, but is typically triggered by positive emotions such as laughter. Although cataplex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37de650f4c6d3ad344746a4f87038837
https://pubmed.ncbi.nlm.nih.gov/28209737
https://pubmed.ncbi.nlm.nih.gov/28209737