Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Jimmy Belotte"'
Autor:
Jimmy Belotte, Brunella Felicetti, Amanda J. Baines, Ahmed YoussefAgha, Luis Rojas-Espaillat, Ana Godoy Ortiz, Diane Provencher, Raúl Márquez Vázquez, Lucia González Cortijo, Xing Zeng
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Maintenance therapy with niraparib, a poly(ADP-ribose) polymerase inhibitor, has been shown to extend progression-free survival in patients with newly diagnosed advanced ovarian cancer who responded to first-line platinum-based ch
Externí odkaz:
https://doaj.org/article/6a0a2a80b0c94cb1a14431371e664115
Autor:
Jimmy Belotte, Nicole M Fletcher, Mohammed G Saed, Mohammed S Abusamaan, Gregory Dyson, Michael P Diamond, Ghassan M Saed
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135739 (2015)
Ovarian cancer is the deadliest of all gynecologic cancers. Recent evidence demonstrates an association between enzymatic activity altering single nucleotide polymorphisms (SNP) with human cancer susceptibility. We sought to evaluate the association
Externí odkaz:
https://doaj.org/article/687ad7d9c17d4fe9a82117309b840c88
Publikováno v:
Case Reports in Obstetrics and Gynecology, Vol 2014 (2014)
Objective. To report a case of successful laparoscopic management of a left ruptured tubal pregnancy in the setting of an ipsilateral ectopic pelvic kidney. Method. Case report was prepared at Wayne State University/Detroit Medical Center. The patien
Externí odkaz:
https://doaj.org/article/d4679d34135b45a993978588b3328303
Autor:
Melissa Hardesty, Thomas Krivak, Gail Wright, Erika Hamilton, Evelyn Fleming, Jimmy Belotte, Erika Keeton, Ping Wang, Aine Clements, Heidi Gray, Gottfried Konecny, Richard Moore, Debra Richardson
Publikováno v:
Gynecologic Oncology. 166:S27-S28
Autor:
Melissa M. Hardesty, Thomas C. Krivak, Gail S. Wright, Erika Hamilton, Evelyn L. Fleming, Jimmy Belotte, Erika K. Keeton, Ping Wang, Divya Gupta, Aine Clements, Heidi J. Gray, Gottfried E. Konecny, Richard G. Moore, Debra L. Richardson
Publikováno v:
Gynecologic oncology. 166(2)
To assess safety and efficacy of niraparib + bevacizumab as a first-line maintenance therapy for patients with newly diagnosed advanced ovarian cancer.This multicenter, phase II, single-arm, open-label study enrolled adult patients with stage IIIB to
Autor:
Heidi J. Gray, Erika Hamilton, Aine Clements, Evelyn Fleming, Jian Chen, Richard G. Moore, Erika Keeton, Debra L. Richardson, Thomas C. Krivak, Melissa M. Hardesty, Gail S. Wright, Jimmy Belotte, Gottfried E. Konecny
Publikováno v:
Gynecologic Oncology. 162:S17
Objectives: Niraparib improves progression-free survival (PFS) in newly diagnosed, recurrent, and heavily pretreated ovarian cancer (OC) in patients (pts) after platinum-based chemotherapy in all biomarker-defined subgroups. Bevacizumab-induced hypox
Autor:
Ghassan M. Saed, Nicole M. Fletcher, Adnan R. Munkarah, Michael P. Diamond, Robert T. Morris, Mitchell Alexis, Jimmy Belotte
Publikováno v:
Reproductive Sciences. 22:38-46
Epithelial ovarian cancer (EOC) is the deadliest gynecologic cancer. Recently, the existence of ovarian cancer stem cells has been reported. Sox2, Nanog and Oct4 are key markers of “stemness”. The objective of this study was to determine whether
Autor:
Michael P. Diamond, Jimmy Belotte, Ghassan M. Saed, Nicole M. Fletcher, Awoniyi O. Awonuga, S. Abuanzeh
Publikováno v:
Reproductive Sciences. 21:823-836
Over the past several years, there has been increasing recognition that pathogenesis of adhesion development includes significant contributions of hypoxia induced at the site of surgery, the resulting oxidative stress, and the subsequent free radical
Autor:
Osama Nusrat, Nicole M. Fletcher, Jimmy Belotte, Ghassan M. Saed, M.G. Saed, Ira Memaj, Michael P. Diamond
Publikováno v:
Reproductive sciences (Thousand Oaks, Calif.). 23(11)
Chemoresistance remains a major challenge in the treatment of ovarian cancer. As part of a survival mechanism, tumor cells have been shown to release proangiogenic factors, such as vascular endothelial growth factor (VEGF), through a mechanism that i
Autor:
Michael P. Diamond, Nancy Levin, Michael A. Tainsky, Ghassan M. Saed, Zhongliang Jiang, Jimmy Belotte, Nicole M. Fletcher, Rouba Ali-Fehmi, Husam M. Abu-Soud
Publikováno v:
Cancer Biomarkers. 10:267-275
Objective: The study sought to identify whether a relationship exists between serum myeloperoxidase (MPO) and free iron with stages of ovarian cancer. Methods: Serum and tissue samples were collected from women with stages I through IV ovarian cancer