Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Jimmy A. Rotolo"'
Autor:
Jimmy A. Rotolo, Chii Shyang Fong, Sahra Bodo, Prashanth K.B. Nagesh, John Fuller, Thivashnee Sharma, Alessandra Piersigilli, Zhigang Zhang, Zvi Fuks, Vijay K. Singh, Richard Kolesnick
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
After 9/11, threat of nuclear attack on American urban centers prompted government agencies to develop medical radiation countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS) and higher-dose gastrointestinal acute radiation syndr
Externí odkaz:
https://doaj.org/article/76b420606de142dd89228218364193f3
Autor:
Richard N. Kolesnick, Philip B. Paty, Zvi Fuks, Joseph O. Deasy, Adriana Haimovitz-Friedman, Stefan Klingler, Sahra Bodo, Jimmy A. Rotolo, John D. Fuller, Christy Li, Sang Gyu Lee, Guoqiang Hua, Kuo-Shun Hsu, Mohammad Adileh, Maria Laura Martin
Tissue survival responses to ionizing radiation are nonlinear with dose, rather yielding tissue-specific descending curves that impede straightforward analysis of biologic effects. Apoptotic cell death often occurs at low doses, while at clinically r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90da75d2b8064d6fd738fd80c5b6e0d
https://doi.org/10.1158/0008-5472.c.6511909
https://doi.org/10.1158/0008-5472.c.6511909
Autor:
Zvi Fuks, Richard Kolesnick, Adriana Haimovitz-Friedman, Jean-Philip Truman, Jerzy Maj, Judith Mesicek, Jimmy A. Rotolo
Supplementary Figures 1-2 from Regulation of Ceramide Synthase–Mediated Crypt Epithelium Apoptosis by DNA Damage Repair Enzymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3201ba46ed0029c3907108fe64dbe256
https://doi.org/10.1158/0008-5472.22383791.v1
https://doi.org/10.1158/0008-5472.22383791.v1
Autor:
Jimmy A. Rotolo, Sahra Bodo, Stefan Klingler, Christy Li, Joseph O. Deasy, Zvi Fuks, John D. Fuller, Guoqiang Hua, Mohammad Adileh, Adriana Haimovitz-Friedman, Sang-gyu Lee, Philip B. Paty, Kuo-Shun Hsu, Maria Laura Martin, Richard Kolesnick
Publikováno v:
Cancer Res
Tissue survival responses to ionizing radiation are nonlinear with dose, rather yielding tissue-specific descending curves that impede straightforward analysis of biologic effects. Apoptotic cell death often occurs at low doses, while at clinically r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b59dbf23677ce2d89757b2ce433286fb
https://doi.org/10.1158/0008-5472.can-19-0312
https://doi.org/10.1158/0008-5472.can-19-0312
Autor:
Hyunmi Lee, Jimmy A Rotolo, Judith Mesicek, Tuula Penate-Medina, Andreas Rimner, Wen-Chieh Liao, Xianglei Yin, Govind Ragupathi, Desiree Ehleiter, Erich Gulbins, Dayong Zhai, John C Reed, Adriana Haimovitz-Friedman, Zvi Fuks, Richard Kolesnick
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0146210 (2015)
Externí odkaz:
https://doaj.org/article/dda7ebbc7ac843c88750940983b5f994
Autor:
Zvi Fuks, Richard Kolesnick, Vijay K. Singh, Prashanth K.B. Nagesh, Zhigang Zhang, Alessandra Piersigilli, Sahra Bodo, Thivashnee Sharma, Chii Shyang Fong, Jimmy A. Rotolo, John D. Fuller
Publikováno v:
JCI Insight, Vol 6, Iss 8 (2021)
JCI Insight
JCI Insight
After 9/11, threat of nuclear attack on American urban centers prompted government agencies to develop medical radiation countermeasures to mitigate hematopoietic acute radiation syndrome (H-ARS) and higher-dose gastrointestinal acute radiation syndr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46c733ff463cf81104a40c94a0662e5
https://doi.org/10.1172/jci.insight.145380
https://doi.org/10.1172/jci.insight.145380
Autor:
Branka Stancevic, Nira Varda-Bloom, Jin Cheng, John D Fuller, Jimmy A Rotolo, Mónica García-Barros, Regina Feldman, Shyam Rao, Ralph R Weichselbaum, Dror Harats, Adriana Haimovitz-Friedman, Zvi Fuks, Michel Sadelain, Richard Kolesnick
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69025 (2013)
These studies define a new mechanism-based approach to radiosensitize tumor cure by single dose radiotherapy (SDRT). Published evidence indicates that SDRT induces acute microvascular endothelial apoptosis initiated via acid sphingomyelinase (ASMase)
Externí odkaz:
https://doaj.org/article/385d5a0a20444620b152eb931564bc92
Autor:
Hyunmi Lee, Jimmy A Rotolo, Judith Mesicek, Tuula Penate-Medina, Andreas Rimner, Wen-Chieh Liao, Xianglei Yin, Govind Ragupathi, Desiree Ehleiter, Erich Gulbins, Dayong Zhai, John C Reed, Adriana Haimovitz-Friedman, Zvi Fuks, Richard Kolesnick
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e19783 (2011)
BACKGROUND:Evidence indicates that Bax functions as a "lipidic" pore to regulate mitochondrial outer membrane permeabilization (MOMP), the apoptosis commitment step, through unknown membrane elements. Here we show mitochondrial ceramide elevation fac
Externí odkaz:
https://doaj.org/article/4cc946576a3b43da8e0f310b42c9ba73
Autor:
Sydney X Lu, Lucy W Kappel, Anne-Marie Charbonneau-Allard, Renée Atallah, Amanda M Holland, Claire Turbide, Vanessa M Hubbard, Jimmy A Rotolo, Marsinay Smith, David Suh, Christopher King, Uttam K Rao, Nury Yim, Johanne L Bautista, Robert R Jenq, Olaf Penack, Il-Kang Na, Chen Liu, George Murphy, Onder Alpdogan, Richard S Blumberg, Fernando Macian, Kathryn V Holmes, Nicole Beauchemin, Marcel R M van den Brink
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21611 (2011)
Allogeneic bone marrow transplantation (allo-BMT) is a potentially curative therapy for a variety of hematologic diseases, but benefits, including graft-versus-tumor (GVT) activity are limited by graft-versus-host-disease (GVHD). Carcinoembryonic ant
Externí odkaz:
https://doaj.org/article/21a1cc5de81c4f2eb8783a27b6d7db01
Autor:
Monica Garcia-Barros, Jeanna Jacobi, Richard Kolesnick, Aviram Mizrachi, Chris Thompson, Zvi Fuks, Alicja Bielawska, Jimmy A. Rotolo, Katia Manova, Regina Feldman, Shyam Rao, Adriana Haimovitz-Friedman, Jacek Bielawska
Publikováno v:
Cellular signalling. 29
Despite great promise, combining anti-angiogenic and conventional anti-cancer drugs has produced limited therapeutic benefit in clinical trials, presumably because mechanisms of anti-angiogenic tissue response remain only partially understood. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c55b5596835289da47797b26533b77e
https://pubmed.ncbi.nlm.nih.gov/27702691
https://pubmed.ncbi.nlm.nih.gov/27702691